Jazz Pharmaceuticals plc (JAZZ)

IE — Healthcare Sector
Peers: RNA  CAI  MRUS  MDGL  ABVX  CYTK  HALO  RYTM  NUVL  AXSM 

Automate Your Wheel Strategy on JAZZ

With Tiblio's Option Bot, you can configure your own wheel strategy including JAZZ - and automate your put writes, covered calls, and full wheel strategy. Just connect one of the supported brokerages: tastytrade, Schwab, TradeStation or Tradier and go.

Start Your Free Trial Now

Key Metrics & Ratings

  • symbol JAZZ
  • Rev/Share 68.5026
  • Book/Share 65.2272
  • PB 2.5589
  • Debt/Equity 0.2735
  • CurrentRatio 1.6516
  • ROIC -0.0256

 

  • MktCap 10142260780.0
  • FreeCF/Share 22.02
  • PFCF 7.5885
  • PE -27.4931
  • Debt/Assets 0.0953
  • DivYield 0
  • ROE -0.0925

 

  • Rating C+
  • Score 2
  • Recommendation Sell
  • P/E Score 1
  • DCF Score 4
  • P/B Score 3
  • D/E Score 2

Recent Analyst Ratings

Type Ticker Analyst Firm Previous Rating Current Rating Previous Price Target Current Price Target Date
Downgrade JAZZ UBS Buy Neutral -- $188 Nov. 24, 2025
Initiation JAZZ Deutsche Bank -- Buy -- $152 July 15, 2025
Upgrade JAZZ UBS Neutral Buy $145 $179 March 7, 2025
Downgrade JAZZ Cantor Fitzgerald Overweight Neutral -- -- Feb. 26, 2025
Upgrade JAZZ Wells Fargo Equal Weight Overweight $130 $170 Feb. 13, 2025
Upgrade JAZZ Morgan Stanley Equal Weight Overweight $140 $175 Dec. 12, 2024

News

Jazz (JAZZ) Up 24.5% Since Last Earnings Report: Can It Continue?
JAZZ
Published: December 05, 2025 by: Zacks Investment Research
Sentiment: Positive

Jazz (JAZZ) reported earnings 30 days ago. What's next for the stock?

Read More
image for news Jazz (JAZZ) Up 24.5% Since Last Earnings Report: Can It Continue?
Jazz Pharmaceuticals to Present Extensive New Data and Real-World Evidence Highlighting Epidiolex® (cannabidiol) Outcomes in Treatment-Resistant Epilepsies at the American Epilepsy Society 2025 Annual Meeting
JAZZ
Published: December 05, 2025 by: PRNewsWire
Sentiment: Neutral

New interim results from the EpiCom trial, a prospective evaluation of behavioral outcomes in patients with tuberous sclerosis complex, suggest improvements in non-seizure outcomes Eight abstracts, including four late-breaking abstracts, underscore Jazz's continued commitment to the epilepsy community and advancing the comprehensive treatment for rare forms of epilepsy For U.S. media and investors only DUBLIN , Dec. 5, 2025 /PRNewswire/ -- Jazz Pharmaceuticals plc (Nasdaq: JAZZ) today announced that eight abstracts, including four that are late-breaking, will be presented on Epidiolex® (cannabidiol) at the American Epilepsy Society (AES) 2025 Annual Meeting, being held December 5-9, 2025, in Atlanta, Georgia. Notable …

Read More
image for news Jazz Pharmaceuticals to Present Extensive New Data and Real-World Evidence Highlighting Epidiolex® (cannabidiol) Outcomes in Treatment-Resistant Epilepsies at the American Epilepsy Society 2025 Annual Meeting
Jazz Pharmaceuticals plc (JAZZ) Presents at Citi Annual Global Healthcare Conference 2025 Transcript
JAZZ
Published: December 02, 2025 by: Seeking Alpha
Sentiment: Neutral

Jazz Pharmaceuticals plc (JAZZ) Presents at Citi Annual Global Healthcare Conference 2025 Transcript

Read More
image for news Jazz Pharmaceuticals plc (JAZZ) Presents at Citi Annual Global Healthcare Conference 2025 Transcript
Why Jazz Pharmaceuticals May Be a Stealth Cannabis Winner
JAZZ
Published: November 26, 2025 by: Zacks Investment Research
Sentiment: Positive

JAZZ leverages Epidiolex's rising sales and its broad drug portfolio to strengthen its position in the evolving medical cannabis market.

Read More
image for news Why Jazz Pharmaceuticals May Be a Stealth Cannabis Winner
JAZZ Hits 52-Week High on Encouraging Gastric Cancer Study Data
JAZZ
Published: November 18, 2025 by: Zacks Investment Research
Sentiment: Positive

Jazz jumps to a 52-week high after HERIZON-GEA-01 shows Ziihera combos delivering meaningful PFS and OS gains in HER2+ GEA.

Read More
image for news JAZZ Hits 52-Week High on Encouraging Gastric Cancer Study Data
Jazz Pharmaceuticals: Stock Soars On Zanidatamab Data - I'm Still On The Fence
JAZZ
Published: November 17, 2025 by: Seeking Alpha
Sentiment: Positive

Jazz Pharmaceuticals plc surged over 20% after positive Phase 3 data for Ziihera in HER2+ gastroesophageal cancer. JAZZ's diversified portfolio, strong Q3 earnings, and upgraded 2025 revenue guidance support its current double-digit billion valuation. Key risks include upcoming patent expiries, new competition for Xywav, and uncertainty around long-term profitability and revenue replacement.

Read More
image for news Jazz Pharmaceuticals: Stock Soars On Zanidatamab Data - I'm Still On The Fence
Jazz Pharmaceuticals' And Zymeworks' Ziihera Success: A Pleasant Surprise
JAZZ, ZYME
Published: November 17, 2025 by: Seeking Alpha
Sentiment: Positive

Jazz Pharmaceuticals plc and Zymeworks Inc. announced positive topline phase 3 results for Ziihera in HER2-positive gastroesophageal adenocarcinoma. Ziihera in combination with chemotherapy and in combination with Tevimbra and chemotherapy outperformed trastuzumab plus chemotherapy, and the triple combination achieved statistically significant overall survival benefit. The GEA indication represents a $2 billion+ a year opportunity for JAZZ and a $300 million opportunity for BeOne, and ZYME stands to benefit by receiving royalties from both partners.

Read More
image for news Jazz Pharmaceuticals' And Zymeworks' Ziihera Success: A Pleasant Surprise
Why Jazz (JAZZ) International Revenue Trends Deserve Your Attention
JAZZ
Published: November 17, 2025 by: Zacks Investment Research
Sentiment: Negative

Review Jazz's (JAZZ) international revenue performance and how it affects the predictions of financial analysts on Wall Street and the future prospects for the stock.

Read More
image for news Why Jazz (JAZZ) International Revenue Trends Deserve Your Attention
JAZZ Beats on Q3 Earnings & Sales, Narrows '25 Sales View
JAZZ
Published: November 06, 2025 by: Zacks Investment Research
Sentiment: Positive

Jazz Pharmaceuticals posts strong Q3 results with higher EPS and sales, aided by a tax benefit and robust neuroscience growth.

Read More
image for news JAZZ Beats on Q3 Earnings & Sales, Narrows '25 Sales View
Iambic Announces Research Collaboration with Jazz Pharmaceuticals for IAM1363 and Zanidatamab Combination Cohort in HER2-Positive Breast Cancer
JAZZ
Published: October 21, 2025 by: Business Wire
Sentiment: Neutral

SAN DIEGO--(BUSINESS WIRE)--Iambic Therapeutics, a clinical-stage life science and technology company developing novel medicines using its AI-driven discovery and development platform, announced it has entered into a research collaboration and drug supply agreement with Jazz Pharmaceuticals. Under the agreement, Jazz will provide zanidatamab (Ziihera®), a HER2-targeted bispecific antibody, at no cost to Iambic for evaluation in combination with IAM1363, Iambic's brain-penetrant HER2 small-molec.

Read More
image for news Iambic Announces Research Collaboration with Jazz Pharmaceuticals for IAM1363 and Zanidatamab Combination Cohort in HER2-Positive Breast Cancer
Here's Why JAZZ Stock Is an Unconventional Cannabis Investment
JAZZ
Published: September 24, 2025 by: Zacks Investment Research
Sentiment: Positive

Jazz Pharma is redefining cannabis investing with Epidiolex, a fast-growing FDA-approved epilepsy drug fueling its growth.

Read More
image for news Here's Why JAZZ Stock Is an Unconventional Cannabis Investment
Jazz Pharmaceuticals Plc (JAZZ) Presents At Wells Fargo 20th Annual Healthcare Conference 2025 Transcript
JAZZ
Published: September 03, 2025 by: Seeking Alpha
Sentiment: Neutral

Jazz Pharmaceuticals plc (NASDAQ:JAZZ ) Wells Fargo 20th Annual Healthcare Conference 2025 September 3, 2025 9:30 AM EDT Company Participants Amal Melhem-Bertrandt Philip Johnson - Executive VP & CFO Conference Call Participants Mohit Bansal - Wells Fargo Securities, LLC, Research Division Presentation Mohit Bansal Senior Equity Analyst Thank you very much for joining us today. My name is Mohit Bansal.

Read More
image for news Jazz Pharmaceuticals Plc (JAZZ) Presents At Wells Fargo 20th Annual Healthcare Conference 2025 Transcript
JAZZ Inks $1B Licensing Deal With Saniona for Epilepsy Drug
JAZZ
Published: August 21, 2025 by: Zacks Investment Research
Sentiment: Neutral

Jazz Pharmaceuticals strikes a $1B licensing deal with Saniona for SAN2355, an epilepsy drug designed to target seizure control more precisely.

Read More
image for news JAZZ Inks $1B Licensing Deal With Saniona for Epilepsy Drug
Don't Overlook Jazz (JAZZ) International Revenue Trends While Assessing the Stock
JAZZ
Published: August 08, 2025 by: Zacks Investment Research
Sentiment: Positive

Evaluate Jazz's (JAZZ) reliance on international revenue to better understand the company's financial stability, growth prospects and potential stock price performance.

Read More
image for news Don't Overlook Jazz (JAZZ) International Revenue Trends While Assessing the Stock
Jazz Pharmaceuticals Announces U.S. FDA Approval of Modeyso™ (dordaviprone) as the First and Only Treatment for Recurrent H3 K27M-mutant Diffuse Midline Glioma
JAZZ
Published: August 06, 2025 by: PRNewsWire
Sentiment: Neutral

Modeyso is the first treatment option for this ultra-rare and aggressive brain tumor, which primarily affects children and young adults Accelerated approval based on an overall response rate in patients with progressive disease following prior therapy Company to host investor webcast on August 27, 2025 For U.S. media and investors only DUBLIN , Aug. 5, 2025 /PRNewswire/ -- Jazz Pharmaceuticals plc (Nasdaq: JAZZ) today announced that the U.S. Food and Drug Administration (FDA) has granted accelerated approval for Modeyso™ (dordaviprone) for the treatment of adult and pediatric patients 1 year of age and older with diffuse midline glioma harboring an …

Read More
image for news Jazz Pharmaceuticals Announces U.S. FDA Approval of Modeyso™ (dordaviprone) as the First and Only Treatment for Recurrent H3 K27M-mutant Diffuse Midline Glioma
US FDA approves Jazz Pharma's drug for rare brain tumor
JAZZ
Published: August 06, 2025 by: Reuters
Sentiment: Positive

The U.S. Food and Drug Administration said on Wednesday that it has approved Jazz Pharmaceuticals' drug to treat diffuse midline glioma, a rare and aggressive tumor, in adults and children aged one year and older.

Read More
image for news US FDA approves Jazz Pharma's drug for rare brain tumor
JAZZ Stock Down on Wider-Than-Expected Q2 Loss, '25 Sales View Cut
JAZZ
Published: August 06, 2025 by: Zacks Investment Research
Sentiment: Negative

Jazz shares slide as Q2 loss widens on Chimerix charge, with 2025 sales outlook trimmed despite higher EPS guidance.

Read More
image for news JAZZ Stock Down on Wider-Than-Expected Q2 Loss, '25 Sales View Cut
Is JAZZ Stock Undervalued At $110?
JAZZ
Published: July 07, 2025 by: Forbes
Sentiment: Positive

Jazz Pharmaceuticals (NASDAQ: JAZZ) is currently trading at approximately $110, having decreased by 11% year-to-date, even after a significant positive development with the conditional European Commission Marketing Authorization for Ziihera (zanidatamab) aimed at advanced HER2-Positive Biliary Tract Cancer. Ziihera is the first HER2-targeted therapy approved in the EU for this condition, with anticipated peak annual sales surpassing $2 billion.

Read More
image for news Is JAZZ Stock Undervalued At $110?
Jazz Pharmaceuticals: I See Big Potential In This Stock As An Investor
JAZZ
Published: July 07, 2025 by: Seeking Alpha
Sentiment: Positive

In recent months, Jazz Pharmaceuticals plc has remained a stock that has seen some decline in attention from retail investors. This comes amid the potential approval of Zepzelca in combination with Tecentriq as a therapy for first-line extensive-stage small cell lung cancer. Meanwhile, the crown jewel of Jazz Pharmaceuticals' oncology franchise is Ziihera, which is superior in efficacy to chemotherapy drugs and Enhertu in the treatment of biliary tract cancer and more.

Read More
image for news Jazz Pharmaceuticals: I See Big Potential In This Stock As An Investor
Why Is Jazz (JAZZ) Up 7.9% Since Last Earnings Report?
JAZZ
Published: June 05, 2025 by: Zacks Investment Research
Sentiment: Positive

Jazz (JAZZ) reported earnings 30 days ago. What's next for the stock?

Read More
image for news Why Is Jazz (JAZZ) Up 7.9% Since Last Earnings Report?
Jazz Pharmaceuticals Reports Clinically Meaningful Long-Term Median Overall Survival Data for Ziihera® (zanidatamab-hrii) in First-Line HER2-Positive Metastatic Gastroesophageal Adenocarcinoma at ASCO 2025
JAZZ
Published: June 02, 2025 by: PRNewsWire
Sentiment: Neutral

Phase 2 trial results continue to show clinically meaningful efficacy and durable responses, including 36.5-month median overall survival after four years of follow-up, with a manageable safety profile Findings presented today at ASCO 2025 and concurrently published in The Lancet Oncology For U.S. media and investors only DUBLIN , June 2, 2025 /PRNewswire/ -- Jazz Pharmaceuticals plc (Nasdaq: JAZZ) today announced long-term data, including the first report of median overall survival (OS) from the Phase 2 trial evaluating Ziihera® (zanidatamab-hrii), a dual HER2-targeted bispecific antibody, in combination with chemotherapy for the investigational use in first-line HER2-positive (IHC 3+ or IHC …

Read More
image for news Jazz Pharmaceuticals Reports Clinically Meaningful Long-Term Median Overall Survival Data for Ziihera® (zanidatamab-hrii) in First-Line HER2-Positive Metastatic Gastroesophageal Adenocarcinoma at ASCO 2025
Jazz Pharmaceuticals: One Step Forward, One Back
JAZZ
Published: May 21, 2025 by: Seeking Alpha
Sentiment: Neutral

Jazz took a step forward with the Chimerix acquisition that should further diversify its revenue base. The oxybate business experienced a setback when Avadel won the appeal that allows Lumryz to compete with Jazz's Xywav in idiopathic hypersomnia. There are three potential catalysts for the oncology business in the second half of the year that should translate to a revenue growth inflection point in 2026.

Read More
image for news Jazz Pharmaceuticals: One Step Forward, One Back
Unlocking Jazz (JAZZ) International Revenues: Trends, Surprises, and Prospects
JAZZ
Published: May 13, 2025 by: Zacks Investment Research
Sentiment: Positive

Evaluate Jazz's (JAZZ) reliance on international revenue to better understand the company's financial stability, growth prospects and potential stock price performance.

Read More
image for news Unlocking Jazz (JAZZ) International Revenues: Trends, Surprises, and Prospects
JAZZ Misses Q1 Earnings & Sales Estimates, Cuts '25 EPS Outlook
JAZZ
Published: May 07, 2025 by: Zacks Investment Research
Sentiment: Negative

Jazz reports dismal first-quarter results. The company revises its 2025 EPS guidance to account for the recently completed Chimerix acquisition.

Read More
image for news JAZZ Misses Q1 Earnings & Sales Estimates, Cuts '25 EPS Outlook
Jazz Pharmaceuticals plc (JAZZ) Q1 2025 Earnings Call Transcript
JAZZ
Published: May 06, 2025 by: Seeking Alpha
Sentiment: Neutral

Jazz Pharmaceuticals plc (NASDAQ:JAZZ ) Q1 2025 Earnings Conference Call May 6, 2025 4:30 PM ET Company Participants Jeff Macdonald - Executive Director, Investor Relations Bruce Cozadd - Chairman and Chief Executive Officer Renee Gala - President and Chief Operating Officer Rob Iannone - Executive Vice President, Global Head of R&D and Chief Medical Officer Phil Johnson - Chief Financial Officer Conference Call Participants Jason Gerberry - Bank of America Jessica Fye - JP Morgan David Amsellem - Piper Sandler Marc Goodman - Leerink Partners. Annabel Samimy - Stifle Joseph Thome - TD Cowen Gregory Renza - RBC Capital Markets …

Read More
image for news Jazz Pharmaceuticals plc (JAZZ) Q1 2025 Earnings Call Transcript
Here's What Key Metrics Tell Us About Jazz (JAZZ) Q1 Earnings
JAZZ
Published: May 06, 2025 by: Zacks Investment Research
Sentiment: Positive

Although the revenue and EPS for Jazz (JAZZ) give a sense of how its business performed in the quarter ended March 2025, it might be worth considering how some key metrics compare with Wall Street estimates and the year-ago numbers.

Read More
image for news Here's What Key Metrics Tell Us About Jazz (JAZZ) Q1 Earnings
Jazz Pharmaceuticals (JAZZ) Q1 Earnings and Revenues Lag Estimates
JAZZ
Published: May 06, 2025 by: Zacks Investment Research
Sentiment: Negative

Jazz Pharmaceuticals (JAZZ) came out with quarterly earnings of $1.68 per share, missing the Zacks Consensus Estimate of $4.51 per share. This compares to earnings of $2.68 per share a year ago.

Read More
image for news Jazz Pharmaceuticals (JAZZ) Q1 Earnings and Revenues Lag Estimates
Here's Why Jazz Pharmaceuticals (JAZZ) is a Strong Value Stock
JAZZ
Published: May 05, 2025 by: Zacks Investment Research
Sentiment: Positive

The Zacks Style Scores offers investors a way to easily find top-rated stocks based on their investing style. Here's why you should take advantage.

Read More
image for news Here's Why Jazz Pharmaceuticals (JAZZ) is a Strong Value Stock
Buy, Sell or Hold JAZZ Stock? Key Tips Ahead of Q1 Earnings
JAZZ
Published: April 30, 2025 by: Zacks Investment Research
Sentiment: Neutral

Investors will likely focus on the sales performance of Jazz Pharmaceuticals' key neuroscience drugs, Xywav and Rylaze, when it reports Q1 results next week.

Read More
image for news Buy, Sell or Hold JAZZ Stock? Key Tips Ahead of Q1 Earnings
3 Unconventional Cannabis Stocks to Watch in 2025
CRBP, JAZZ, PM
Published: April 29, 2025 by: Zacks Investment Research
Sentiment: Positive

Think cannabis investing is all hype? These three unconventional stocks could change your mind - and your portfolio - in 2025.

Read More
image for news 3 Unconventional Cannabis Stocks to Watch in 2025

About Jazz Pharmaceuticals plc (JAZZ)

  • IPO Date 2007-06-01
  • Website https://www.jazzpharma.com
  • Industry Biotechnology
  • CEO Renee D. Gala
  • Employees 2800

Jazz Pharmaceuticals plc, a biopharmaceutical company, identifies, develops, and commercializes pharmaceutical products for various unmet medical needs in the United States, Europe, and internationally. The company has a portfolio of products and product candidates with a focus in the areas of neuroscience, including sleep medicine and movement disorders; and in oncology, including hematologic and solid tumors. Its lead marketed products include Xyrem, an oral solution for the treatment of cataplexy and excessive daytime sleepiness (EDS) in narcolepsy patients seven years of age and older; Sunosi for the treatment of EDS in patients with narcolepsy and obstructive sleep apnea; Erwinaze to treat acute lymphoblastic leukemia; Defitelio for the treatment of adult and pediatric patients with hepatic veno-occlusive disease; Vyxeos liposome for injection, a product for the treatment of adults with newly-diagnosed therapy-related acute myeloid leukemia; and Zepzelca for the treatment of adult patients with metastatic small cell lung cancer. The company also offers Xywav, an oxybate product candidate, to treat EDS and cataplexy with narcolepsy and idiopathic hypersomnia; JZP-324, a low sodium oxybate formulation with the potential to provide a clinically meaningful option for narcolepsy patients; JZP385, a T-type calcium channel modulator, for the treatment of essential tremor; JZP458, a recombinant Erwinia asparaginase, for use as a component of a multi-agent chemotherapeutic regimen in the treatment of pediatric and adult patients; and JZP150 for treatment of post-traumatic stress disorder. The company has licensing and collaboration agreements with ImmunoGen, Inc.; Codiak BioSciences, Inc.; Pfenex, Inc.; XL-protein GmbH; and Redx Pharma plc. Jazz Pharmaceuticals plc was incorporated in 2003 and is headquartered in Dublin, Ireland.