AstraZeneca PLC (AZN)

GB — Healthcare Sector
Peers: NVS  GSK  RHHBY  BMY  SNY  MRK  GILD  JNJ  ABBV  LLY  PFE  AMGN 

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Key Metrics & Ratings

  • symbol AZN
  • Rev/Share 18.9481
  • Book/Share 15.7158
  • PB 13.0543
  • Debt/Equity 0.6103
  • CurrentRatio 0.9381
  • ROIC 0.1303

 

  • MktCap 635430178846.0
  • FreeCF/Share 3.4102
  • PFCF 60.1078
  • PE 62.1334
  • Debt/Assets 0.2604
  • DivYield 0.013
  • ROE 0.2268

 

  • Rating B+
  • Score 3
  • Recommendation Neutral
  • P/E Score 1
  • DCF Score 4
  • P/B Score 1
  • D/E Score 2

Recent Analyst Ratings

Type Ticker Analyst Firm Previous Rating Current Rating Previous Price Target Current Price Target Date
Initiation AZN Citigroup -- Buy -- -- Jan. 27, 2026
Resumed AZN Jefferies -- Buy -- -- Oct. 27, 2025
Downgrade AZN Deutsche Bank Hold Sell -- -- Oct. 16, 2025
Initiation AZN Exane BNP Paribas -- Outperform -- $75 April 15, 2025
Upgrade AZN UBS Neutral Buy -- -- Feb. 13, 2025
Initiation AZN Morgan Stanley -- Overweight -- -- Feb. 12, 2025
Downgrade AZN Deutsche Bank Hold Sell -- -- Sept. 13, 2024

News

AstraZeneca vs. Pfizer: Which Pharma Giant Has the Edge in 2026?
AZN, PFE
Published: February 20, 2026 by: Zacks Investment Research
Sentiment: Positive

AZN's stronger growth outlook and 2030 revenue target may outshine PFE's yield and cheaper valuation.

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image for news AstraZeneca vs. Pfizer: Which Pharma Giant Has the Edge in 2026?
Shore Capital downgrades AstraZeneca as R&D spending dampens earnings trajectory
AZN
Published: February 13, 2026 by: Proactive Investors
Sentiment: Negative

Shore Capital downgraded AstraZeneca PLC (LSE:AZN, NASDAQ:AZN) to 'hold' from 'buy', citing a less favourable earnings trajectory as the drugmaker prioritises revenue growth through escalating research spending. The broker warns the current valuation looks full at 20 times forecast 2026 earnings despite confidence the company can exceed its $80 billion 2030 revenue target.

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image for news Shore Capital downgrades AstraZeneca as R&D spending dampens earnings trajectory
A Closer Look at Healthcare Sector Earnings: AZN vs. EW vs. ZBH
AZN, EW, ZBH
Published: February 12, 2026 by: MarketBeat
Sentiment: Positive

More than just a financial check-up, earnings for companies in the healthcare sector offer a key window for investors into a firm's pipeline and development progress. Even well-established, stable firms in the healthcare space can surprise with growth upon the release of a new blockbuster drug or medical device, and earnings periods are an opportunity for management to provide insight and commentary beyond what investors might expect from FDA notices of approvals, for example.

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image for news A Closer Look at Healthcare Sector Earnings: AZN vs. EW vs. ZBH
Citi maintains 'buy' on AstraZeneca with £170 target, cites sector-best pipeline
AZN
Published: February 11, 2026 by: Proactive Investors
Sentiment: Positive

Double-digit earnings outlook and strong trial momentum support top pick status AstraZeneca PLC (LSE:AZN, NASDAQ:AZN) remains a top pick at Citi following full-year results and 2026 guidance that the bank described as “reassuring”, with a reiterated target price of £170 and unchanged earnings forecasts. Management confirmed expectations for low double-digit earnings growth in 2026, aligning with consensus, while the medium single- to high single-digit revenue outlook was ahead of market forecasts.

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image for news Citi maintains 'buy' on AstraZeneca with £170 target, cites sector-best pipeline
AstraZeneca: Q4 Earnings Analysis - Ticks The Boxes, Upgrading To Buy
AZN
Published: February 10, 2026 by: Seeking Alpha
Sentiment: Positive

AstraZeneca PLC delivered robust 2025 results, with 9% product sales growth and a 23.4% operating margin, and raised its dividend. AZN targets $80bn in revenues by 2030, driven by oncology, pipeline launches, and a $50bn US investment; management expresses increasing confidence. Patent expirations loom for key drugs, but pipeline assets and AI-driven innovation are expected to offset risks and sustain growth.

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image for news AstraZeneca: Q4 Earnings Analysis - Ticks The Boxes, Upgrading To Buy
AstraZeneca PLC (AZN) Q4 2025 Earnings Call Transcript
AZN
Published: February 10, 2026 by: Seeking Alpha
Sentiment: Neutral

AstraZeneca PLC (AZN) Q4 2025 Earnings Call Transcript

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image for news AstraZeneca PLC (AZN) Q4 2025 Earnings Call Transcript
AZN Q4 Earnings Miss Estimates, Stock Up on Robust 2026 Growth Outlook
AZN
Published: February 10, 2026 by: Zacks Investment Research
Sentiment: Negative

AZN misses Q4 EPS and sales estimates, but rallies after projecting mid-to-high single-digit revenue growth and low double-digit EPS growth for 2026.

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image for news AZN Q4 Earnings Miss Estimates, Stock Up on Robust 2026 Growth Outlook
Here's What Key Metrics Tell Us About Astrazeneca (AZN) Q4 Earnings
AZN
Published: February 10, 2026 by: Zacks Investment Research
Sentiment: Positive

The headline numbers for Astrazeneca (AZN) give insight into how the company performed in the quarter ended December 2025, but it may be worthwhile to compare some of its key metrics to Wall Street estimates and the year-ago actuals.

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image for news Here's What Key Metrics Tell Us About Astrazeneca (AZN) Q4 Earnings
Will These 5 Drug Bigwigs Surpass Q4 Earnings Forecasts?
AZN, GILD, INCY, MRNA, VRTX
Published: February 09, 2026 by: Zacks Investment Research
Sentiment: Positive

Let's look at five pharma and biotech companies, AZN, INCY, GILD, VRTX and MRNA, which are scheduled to release their fourth-quarter 2025 results this week.

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image for news Will These 5 Drug Bigwigs Surpass Q4 Earnings Forecasts?
Countdown to Astrazeneca (AZN) Q4 Earnings: A Look at Estimates Beyond Revenue and EPS
AZN
Published: February 05, 2026 by: Zacks Investment Research
Sentiment: Positive

Besides Wall Street's top-and-bottom-line estimates for Astrazeneca (AZN), review projections for some of its key metrics to gain a deeper understanding of how the company might have fared during the quarter ended December 2025.

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image for news Countdown to Astrazeneca (AZN) Q4 Earnings: A Look at Estimates Beyond Revenue and EPS
AstraZeneca to Report Q4 Earnings: What's in Store for the Stock?
AZN
Published: February 05, 2026 by: Zacks Investment Research
Sentiment: Positive

AZN gears up for Q4 results as cancer, diabetes and rare disease drugs drive sales expectations ahead of the Feb. 10 earnings report.

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image for news AstraZeneca to Report Q4 Earnings: What's in Store for the Stock?
FDA Rejects AZN's Saphnelo SubQ Formulation, Priority Tag to Datroway
AZN
Published: February 04, 2026 by: Zacks Investment Research
Sentiment: Neutral

AstraZeneca wins FDA priority review for Datroway in triple-negative breast cancer, while Saphnelo SC receives a complete response letter.

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image for news FDA Rejects AZN's Saphnelo SubQ Formulation, Priority Tag to Datroway
AstraZeneca's Initial Application for Lupus Injection Turned Down by FDA
AZN
Published: February 03, 2026 by: WSJ
Sentiment: Negative

The company is working with the U.S. regulator to move forward with an updated application, adding a decision is expected in the first half of 2026.

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image for news AstraZeneca's Initial Application for Lupus Injection Turned Down by FDA
AZN Obesity Pipeline to Get a Boost From Deal With China's CSPC
AZN
Published: February 02, 2026 by: Zacks Investment Research
Sentiment: Positive

AstraZeneca deepens its obesity push with an eight-program deal with China's CSPC, securing rights to a once-monthly injectable weight-management pipeline.

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image for news AZN Obesity Pipeline to Get a Boost From Deal With China's CSPC
Winners & Losers: The ETF Playbook to Glide Trump's Great Healthcare Plan
AZN, HQY, JNJ, LLY, MRK, NVS, WMT
Published: January 19, 2026 by: Zacks Investment Research
Sentiment: Neutral

Trump's Great Healthcare Plan redraws healthcare winners and losers - here's how ETFs like IHE could benefit as middlemen face pressure.

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image for news Winners & Losers: The ETF Playbook to Glide Trump's Great Healthcare Plan
UK drugmakers face tougher test as pharma rally cools
AZN
Published: January 16, 2026 by: Proactive Investors
Sentiment: Negative

The next earnings season for European pharmaceuticals is shaping up as a test of discipline rather than momentum, with UK stocks firmly in the spotlight. That is the message from Deutsche Bank, which says the sector's strong start to the year has already pulled forward some optimism.

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image for news UK drugmakers face tougher test as pharma rally cools
AstraZeneca to acquire Modella AI to speed oncology drug research
AZN
Published: January 13, 2026 by: Reuters
Sentiment: Positive

AstraZeneca has agreed to buy Boston-based Modella AI, the companies said on Tuesday, as the drug industry increases its use of artificial intelligence to accelerate the discovery of new drugs.

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image for news AstraZeneca to acquire Modella AI to speed oncology drug research
Modella AI Announces Acquisition by AstraZeneca to Advance AI-Driven Oncology R&D at Global Scale
AZN
Published: January 13, 2026 by: Business Wire
Sentiment: Neutral

BOSTON--(BUSINESS WIRE)-- #AstraZeneca--Modella AI Announces Acquisition by AstraZeneca to Advance AI-Driven Oncology R&D at Global Scale.

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image for news Modella AI Announces Acquisition by AstraZeneca to Advance AI-Driven Oncology R&D at Global Scale
Healthy Returns: What to expect from pharma at the JPM conference
AMGN, AZN, BMY, LLY, MRK, NVO, PFE
Published: January 09, 2026 by: CNBC
Sentiment: Positive

At the JPMorgan Healthcare Conference, drugmakers are expected to roll out key business and drug pipeline updates and splashy M&A deals.

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image for news Healthy Returns: What to expect from pharma at the JPM conference
Here's Why Astrazeneca (AZN) is a Strong Momentum Stock
AZN
Published: January 08, 2026 by: Zacks Investment Research
Sentiment: Positive

The Zacks Style Scores offers investors a way to easily find top-rated stocks based on their investing style. Here's why you should take advantage.

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image for news Here's Why Astrazeneca (AZN) is a Strong Momentum Stock
JNJ vs. AZN: Which Drug Stock Comes Out on Top for Investors?
AZN, JNJ
Published: January 06, 2026 by: Zacks Investment Research
Sentiment: Positive

J&J's diversified pharma and MedTech strength stacks up against AstraZeneca's oncology-led growth as investors weigh stability versus faster expansion.

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image for news JNJ vs. AZN: Which Drug Stock Comes Out on Top for Investors?
Astrazeneca (AZN) is a Top-Ranked Growth Stock: Should You Buy?
AZN
Published: January 06, 2026 by: Zacks Investment Research
Sentiment: Positive

Whether you're a value, growth, or momentum investor, finding strong stocks becomes easier with the Zacks Style Scores, a top feature of the Zacks Premium research service.

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image for news Astrazeneca (AZN) is a Top-Ranked Growth Stock: Should You Buy?
LSEG, Rolls-Royce, AstraZeneca and Rightmove spotlighted as investment bank eyes potential winners for 2026
AZN, RTMVY, RYCEY, LDNXF, LSEGY
Published: December 24, 2025 by: Proactive Investors
Sentiment: Positive

The festive period is, for some, a time for taking stock of what's happened in the past year - for others, though, its a time to pick stocks for the year ahead. So it is, then, that it's the season for looking ahead.

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image for news LSEG, Rolls-Royce, AstraZeneca and Rightmove spotlighted as investment bank eyes potential winners for 2026
ABBV vs. AZN: Which Pharma Stock is the Better Investment Now?
ABBV, AZN
Published: December 23, 2025 by: Zacks Investment Research
Sentiment: Negative

AbbVie and AstraZeneca both bring blockbuster drugs, deep pipelines and risks, but their growth paths, pressures and priorities now sharply diverge.

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image for news ABBV vs. AZN: Which Pharma Stock is the Better Investment Now?
Here's Why Astrazeneca (AZN) is a Strong Value Stock
AZN
Published: December 23, 2025 by: Zacks Investment Research
Sentiment: Positive

Wondering how to pick strong, market-beating stocks for your investment portfolio? Look no further than the Zacks Style Scores.

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image for news Here's Why Astrazeneca (AZN) is a Strong Value Stock
5 Big Drug Stocks That May Continue to Outperform in 2026
ABBV, AMGN, AZN, JNJ, LLY
Published: December 23, 2025 by: Zacks Investment Research
Sentiment: Positive

Five big drugmakers, including LLY and JNJ, are riding innovation, dealmaking and pipeline momentum that could help them keep outperforming in 2026.

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image for news 5 Big Drug Stocks That May Continue to Outperform in 2026
AZN, Daiichi's Enhertu Gets Breakthrough Tag for Expanded Cancer Use
AZN
Published: December 22, 2025 by: Zacks Investment Research
Sentiment: Positive

AstraZeneca's Enhertu wins FDA Breakthrough tag for expanded use in breast cancer, while a late-stage study on ceralasertib + Imfinzi in lung cancer misses its goal.

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image for news AZN, Daiichi's Enhertu Gets Breakthrough Tag for Expanded Cancer Use
AstraZeneca Drug Combination Falls Short of Goal in Lung-Cancer Trial
AZN
Published: December 22, 2025 by: WSJ
Sentiment: Negative

The pharmaceutical company said its ceralasertib combination didn't meet the primary goal of a late-stage clinical trial for advanced lung cancer.

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image for news AstraZeneca Drug Combination Falls Short of Goal in Lung-Cancer Trial
AstraZeneca's ceralasertib-Imfinzi combo misses survival target in lung cancer trial
AZN
Published: December 22, 2025 by: Reuters
Sentiment: Negative

AstraZeneca said on Monday that a late‑stage trial testing Imfinzi in combination with ceralasertib failed to improve overall survival in patients with previously treated advanced non‑small cell lung cancer.

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image for news AstraZeneca's ceralasertib-Imfinzi combo misses survival target in lung cancer trial
This year's biotech laggards primed for 2026 recovery, says Goldman Sachs' Richter
ALNY, AMGN, ARGX, AZN, IBB
Published: December 19, 2025 by: CNBC Television
Sentiment: Neutral

CNBC's “Closing Bell Overtime” team discusses why the biotech recovery may continue into 2026 with Salveen Richter, lead U.S. biotech analyst at Goldman Sachs Research.

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image for news This year's biotech laggards primed for 2026 recovery, says Goldman Sachs' Richter

About AstraZeneca PLC (AZN)

  • IPO Date 1993-05-12
  • Website https://www.astrazeneca.com
  • Industry Drug Manufacturers - General
  • CEO Pascal Claude Roland Soriot
  • Employees 94300

AstraZeneca PLC, a biopharmaceutical company, focuses on the discovery, development, manufacture, and commercialization of prescription medicines. The company's marketed products include Tagrisso, Imfinzi, Lynparza, Calquence, Enhertu, Orpathys, Truqap, Zoladex, Faslodex, Farxiga, Brilinta, Lokelma, Roxadustat, Andexxa, Crestor, Seloken, Onglyza, Bydureon, Fasenra, Breztri, Symbicort, Saphnelo, Tezspire, Pulmicort, Bevespi, and Daliresp for cardiovascular, renal, metabolism, and oncology. Its marketed products also comprise Vaxzevria, Beyfortus, Synagis, FluMist, Soliris, Ultomiris, Strensiq, Koselugo, and Kanuma for covid-19 and rare disease. The company serves primary care and specialty care physicians through distributors and local representative offices in the United Kingdom, rest of Europe, the Americas, Asia, Africa, and Australasia. It has a collaboration agreement with Neurimmune AG to develop and commercialize NI006; BenevolentAI for drug discovery for systemic lupus erythematosus; Lunit for developing AI-Powered Digital Pathology Risk Assessment Tools for NSCLC; and Absci Corporation for AI-driven drug discovery against an oncology target. The company was formerly known as Zeneca Group PLC and changed its name to AstraZeneca PLC in April 1999. AstraZeneca PLC was incorporated in 1992 and is headquartered in Cambridge, the United Kingdom.