AstraZeneca PLC (AZN)

GB — Healthcare Sector
Peers: NVS  GSK  RHHBY  BMY  SNY  MRK  GILD  JNJ  ABBV  LLY  PFE  AMGN 

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Key Metrics & Ratings

  • symbol AZN
  • Rev/Share 18.5878
  • Book/Share 14.7006
  • PB 6.226
  • Debt/Equity 0.7118
  • CurrentRatio 0.8792
  • ROIC 0.121

 

  • MktCap 283267792806.0
  • FreeCF/Share 3.5646
  • PFCF 25.412
  • PE 30.3966
  • Debt/Assets 0.2854
  • DivYield 0.0171
  • ROE 0.218

 

  • Rating B+
  • Score 3
  • Recommendation Neutral
  • P/E Score 2
  • DCF Score 4
  • P/B Score 2
  • D/E Score 1

Recent Analyst Ratings

Type Ticker Analyst Firm Previous Rating Current Rating Previous Price Target Current Price Target Date
Resumed AZN Jefferies -- Buy -- -- Oct. 27, 2025
Downgrade AZN Deutsche Bank Hold Sell -- -- Oct. 16, 2025
Initiation AZN Exane BNP Paribas -- Outperform -- $75 April 15, 2025
Upgrade AZN UBS Neutral Buy -- -- Feb. 13, 2025
Initiation AZN Morgan Stanley -- Overweight -- -- Feb. 12, 2025
Downgrade AZN Deutsche Bank Hold Sell -- -- Sept. 13, 2024

News

AZN, Daiichi's Enhertu Gets Breakthrough Tag for Expanded Cancer Use
AZN
Published: December 22, 2025 by: Zacks Investment Research
Sentiment: Positive

AstraZeneca's Enhertu wins FDA Breakthrough tag for expanded use in breast cancer, while a late-stage study on ceralasertib + Imfinzi in lung cancer misses its goal.

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image for news AZN, Daiichi's Enhertu Gets Breakthrough Tag for Expanded Cancer Use
AstraZeneca Drug Combination Falls Short of Goal in Lung-Cancer Trial
AZN
Published: December 22, 2025 by: WSJ
Sentiment: Negative

The pharmaceutical company said its ceralasertib combination didn't meet the primary goal of a late-stage clinical trial for advanced lung cancer.

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image for news AstraZeneca Drug Combination Falls Short of Goal in Lung-Cancer Trial
AstraZeneca's ceralasertib-Imfinzi combo misses survival target in lung cancer trial
AZN
Published: December 22, 2025 by: Reuters
Sentiment: Negative

AstraZeneca said on Monday that a late‑stage trial testing Imfinzi in combination with ceralasertib failed to improve overall survival in patients with previously treated advanced non‑small cell lung cancer.

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image for news AstraZeneca's ceralasertib-Imfinzi combo misses survival target in lung cancer trial
This year's biotech laggards primed for 2026 recovery, says Goldman Sachs' Richter
ALNY, AMGN, ARGX, AZN, IBB
Published: December 19, 2025 by: CNBC Television
Sentiment: Neutral

CNBC's “Closing Bell Overtime” team discusses why the biotech recovery may continue into 2026 with Salveen Richter, lead U.S. biotech analyst at Goldman Sachs Research.

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image for news This year's biotech laggards primed for 2026 recovery, says Goldman Sachs' Richter
Trump to announce new drug-pricing deals later today
ABBV, AMGN, AZN, BMY, GILD, LLY, MRK, NVO, PFE
Published: December 19, 2025 by: Market Watch
Sentiment: Positive

The White House is getting ready to announce more deals with drugmakers aimed at lowering drug prices.

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image for news Trump to announce new drug-pricing deals later today
AZN, Daiichi's Enhertu Gets FDA Nod for First-Line Breast Cancer
AZN
Published: December 16, 2025 by: Zacks Investment Research
Sentiment: Positive

AstraZeneca's Enhertu wins FDA nod as a first-line treatment for HER2-positive metastatic breast cancer.

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image for news AZN, Daiichi's Enhertu Gets FDA Nod for First-Line Breast Cancer
Here's Why Astrazeneca (AZN) is a Strong Growth Stock
AZN
Published: December 16, 2025 by: Zacks Investment Research
Sentiment: Positive

Whether you're a value, growth, or momentum investor, finding strong stocks becomes easier with the Zacks Style Scores, a top feature of the Zacks Premium research service.

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image for news Here's Why Astrazeneca (AZN) is a Strong Growth Stock
AstraZeneca: A Rare Compound Growth Opportunity In Biopharma
AZN
Published: December 10, 2025 by: Seeking Alpha
Sentiment: Neutral

AstraZeneca (AZN) offers a rare, secular growth profile in biopharma, underpinned by a diversified commercial asset base and layered patent expirations. AZN faces a minor patent cliff, with most key products' loss of exclusivity in the 2030s, and rapidly growing therapies offsetting near-term risks. The pipeline is robust and diversified, targeting 20 new molecular entities by 2030, supporting management's ambition to nearly double revenues to $80B.

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image for news AstraZeneca: A Rare Compound Growth Opportunity In Biopharma
AZN's Baxdrostat Gets FDA Priority Tag for Uncontrolled Hypertension
AZN
Published: December 03, 2025 by: Zacks Investment Research
Sentiment: Positive

AstraZeneca's NDA for baxdrostat gains FDA priority review for treating hard-to-control hypertension. A decision is due in the second quarter of 2026.

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image for news AZN's Baxdrostat Gets FDA Priority Tag for Uncontrolled Hypertension
Why Astrazeneca (AZN) is a Top Momentum Stock for the Long-Term
AZN
Published: December 03, 2025 by: Zacks Investment Research
Sentiment: Positive

Wondering how to pick strong, market-beating stocks for your investment portfolio? Look no further than the Zacks Style Scores.

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image for news Why Astrazeneca (AZN) is a Top Momentum Stock for the Long-Term
Baxdrostat New Drug Application accepted under FDA Priority Review in the US for patients with hard-to-control hypertension
AZN
Published: December 02, 2025 by: Business Wire
Sentiment: Neutral

WILMINGTON, Del.--(BUSINESS WIRE)--AstraZeneca's New Drug Application (NDA) for baxdrostat has been accepted for Priority Review by the US Food and Drug Administration (FDA) in the US for the treatment of adult patients with hard-to-control (uncontrolled or treatment resistant) hypertension as an add-on to other antihypertensive medicines when these do not provide adequate lowering of blood pressure. The Prescription Drug User Fee Act (PDUFA) date is anticipated during the second quarter of 202.

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image for news Baxdrostat New Drug Application accepted under FDA Priority Review in the US for patients with hard-to-control hypertension
Here's Why Astrazeneca (AZN) is a Strong Growth Stock
AZN
Published: November 28, 2025 by: Zacks Investment Research
Sentiment: Positive

The Zacks Style Scores offers investors a way to easily find top-rated stocks based on their investing style. Here's why you should take advantage.

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image for news Here's Why Astrazeneca (AZN) is a Strong Growth Stock
AstraZeneca or Merck: Which Oncology Giant Has the Edge?
AZN, MRK
Published: November 27, 2025 by: Zacks Investment Research
Sentiment: Positive

AZN and MRK boast major oncology strengths and expanding pipelines amid shifting market dynamics in this pharma matchup.

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image for news AstraZeneca or Merck: Which Oncology Giant Has the Edge?
Why Astrazeneca (AZN) is a Top Value Stock for the Long-Term
AZN
Published: November 27, 2025 by: Zacks Investment Research
Sentiment: Positive

Whether you're a value, growth, or momentum investor, finding strong stocks becomes easier with the Zacks Style Scores, a top feature of the Zacks Premium research service.

Read More
image for news Why Astrazeneca (AZN) is a Top Value Stock for the Long-Term
Why Medicare price negotiations matter for Novo Nordisk, AstraZeneca, and other European pharma companies
AZN, NVO
Published: November 26, 2025 by: CNBC
Sentiment: Neutral

The IRA from 2022 allows the CMS to negotiate prices for a number of drugs each year for patients in Medicare. Late Tuesday, the agency announced newly negotiated prices for 15 blockbuster drugs from 2027, including Novo Nordisk's mega bestseller Ozempic which will see a 71% discount to its list price.

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image for news Why Medicare price negotiations matter for Novo Nordisk, AstraZeneca, and other European pharma companies
AstraZeneca Doubles Down On US Biologics Buildout As Drug Discovery Partnership Grows
AZN
Published: November 24, 2025 by: Benzinga
Sentiment: Positive

Hong Kong-based Harbour BioMed announced on Sunday an update and advancement of its global strategic collaboration with AstraZeneca Plc (NASDAQ: AZN), initially established in March 2025.

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image for news AstraZeneca Doubles Down On US Biologics Buildout As Drug Discovery Partnership Grows
AstraZeneca to invest $2 billion as part of US manufacturing push
AZN
Published: November 21, 2025 by: Reuters
Sentiment: Positive

AstraZeneca said on Friday it will invest $2 billion to expand its manufacturing footprint in Maryland as part of its previously announced $50 billion plan to expand manufacturing and research capabilities in the U.S. by 2030.

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image for news AstraZeneca to invest $2 billion as part of US manufacturing push
AstraZeneca plans $2 billion manufacturing investment in Maryland, supporting 2,600 jobs and catalyzing economic growth
AZN
Published: November 21, 2025 by: Business Wire
Sentiment: Neutral

WILMINGTON, Del.--(BUSINESS WIRE)--AstraZeneca today announces plans to invest $2 billion to expand its long-standing manufacturing footprint in Maryland. This includes a significant expansion of its flagship biologics manufacturing facility in Frederick and construction of a new state-of-the-art facility in Gaithersburg for the development and clinical supply of innovative molecules to be used in clinical trials. The investment will support 2,600 jobs across the two sites in the state includin.

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image for news AstraZeneca plans $2 billion manufacturing investment in Maryland, supporting 2,600 jobs and catalyzing economic growth
AZN Wins FDA Nod for Expanded Use of Rare Disease Drug, Koselugo
AZN
Published: November 21, 2025 by: Zacks Investment Research
Sentiment: Positive

AstraZeneca secures FDA approval to expand Koselugo's use to treat adult NF1 patients with inoperable PN.

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image for news AZN Wins FDA Nod for Expanded Use of Rare Disease Drug, Koselugo
Biopharma companies have confidence in their ability to do deals: BMO's Evan Seigerman
ABBV, AZN, JNJ, LLY, MRK, NVO, PFE, XLV
Published: November 14, 2025 by: CNBC Television
Sentiment: Positive

Evan Seigerman, BMO Capital Markets head of health care research, joins 'Power Lunch' to discuss what's behind the recent move in health care stocks, the state of play with GLP-1s and much more.

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image for news Biopharma companies have confidence in their ability to do deals: BMO's Evan Seigerman
Why Astrazeneca (AZN) is a Top Growth Stock for the Long-Term
AZN
Published: November 12, 2025 by: Zacks Investment Research
Sentiment: Positive

The Zacks Style Scores offers investors a way to easily find top-rated stocks based on their investing style. Here's why you should take advantage.

Read More
image for news Why Astrazeneca (AZN) is a Top Growth Stock for the Long-Term
AstraZeneca's Investigational Hypertension Drug Shows Significant Blood Pressure Control In Pivotal Trial
AZN
Published: November 10, 2025 by: Benzinga
Sentiment: Positive

AstraZeneca Plc (NASDAQ:AZN) shared on Monday full data from the Bax24 Phase 3 trial of once-daily 2mg baxdrostat versus placebo, on the reduction of ambulatory systolic blood pressure (SBP), as well as safety and tolerability in participants with resistant hypertension.

Read More
image for news AstraZeneca's Investigational Hypertension Drug Shows Significant Blood Pressure Control In Pivotal Trial
AstraZeneca: Solid Results, But Risks Emerge (Rating Downgrade)
AZN
Published: November 06, 2025 by: Seeking Alpha
Sentiment: Negative

The highlight of AstraZeneca's latest results is the maintained full-year outlook despite the recent US drug pricing agreement. AstraZeneca's financials remain robust, with double-digit revenue and EPS growth, but Q4 2025 is expected to show slower or even negative EPS growth. Risks could also stem from U.S. pricing pressures and potentially unresolved tax issues in China. Additionally, stretched valuations and limited near-term upside, prompt a Hold rating.

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image for news AstraZeneca: Solid Results, But Risks Emerge (Rating Downgrade)
AZN Q3 Earnings Top Estimates, Sales Rise As Most Key Drugs Outperform
AZN
Published: November 06, 2025 by: Zacks Investment Research
Sentiment: Positive

AstraZeneca posts strong Q3 results. Core earnings and revenues beat estimates as key drugs like Tagrisso, Imfinzi and Farxiga fuel broad-based growth.

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image for news AZN Q3 Earnings Top Estimates, Sales Rise As Most Key Drugs Outperform
AstraZeneca climbs to net all-time high after US deal reassurance
AZN
Published: November 06, 2025 by: Proactive Investors
Sentiment: Positive

AstraZeneca PLC (LSE:AZN, NASDAQ:AZN) posted what analysts called a very solid set of third-quarter results, but the shares barely moved in early morning trading as the City waited for more details on the analyst call. In afternoon trading, shares in the giant drugmaker jumped over 4% to a new all time high above 12,990p.

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image for news AstraZeneca climbs to net all-time high after US deal reassurance
Compared to Estimates, Astrazeneca (AZN) Q3 Earnings: A Look at Key Metrics
AZN
Published: November 06, 2025 by: Zacks Investment Research
Sentiment: Positive

Although the revenue and EPS for Astrazeneca (AZN) give a sense of how its business performed in the quarter ended September 2025, it might be worth considering how some key metrics compare with Wall Street estimates and the year-ago numbers.

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image for news Compared to Estimates, Astrazeneca (AZN) Q3 Earnings: A Look at Key Metrics
AstraZeneca wins shareholder backing for NYSE listing in US pivot
AZN
Published: November 03, 2025 by: Reuters
Sentiment: Positive

AstraZeneca shareholders approved a direct listing of the drugmaker's shares on the New York Stock Exchange on Monday, giving it access to a deeper capital pool.

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image for news AstraZeneca wins shareholder backing for NYSE listing in US pivot
AstraZeneca wins shareholder backing for NYSE listing as drugmaker pivots to US
AZN
Published: November 03, 2025 by: Reuters
Sentiment: Positive

AstraZeneca shareholders approved a direct listing of the drugmaker's shares on the New York Stock Exchange on Monday, giving it access to a deeper capital pool.

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image for news AstraZeneca wins shareholder backing for NYSE listing as drugmaker pivots to US
BioInvent to Present Early Phase 2a Data from Ongoing Trial with Triple Combination of BI-1206, Rituximab, and Calquence in r/r NHL, at ASH 2025
AZN
Published: November 03, 2025 by: Accesswire
Sentiment: Neutral

LUND, SE / ACCESS Newswire / November 3, 2025 / BioInvent International AB ("BioInvent")(STO:BINV)(Nasdaq Stockholm:BINV), a biotech company focused on the discovery and development of novel and first-in-class immune-modulatory antibodies for cancer immunotherapy, today announced that it will present new data from the safety run-in portion of its ongoing trial evaluating BI-1206 in combination with rituximab and Calquence ® (acalabrutinib) for the treatment of non-Hodgkin's lymphoma (NHL) in a poster at the upcoming 2025 American Society of Hematology (ASH) Annual Meeting, taking place December 6-9, 2025, in Orlando, Florida. Abstract data (as of August 4, 2025) published in the November …

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image for news BioInvent to Present Early Phase 2a Data from Ongoing Trial with Triple Combination of BI-1206, Rituximab, and Calquence in r/r NHL, at ASH 2025
AstraZeneca to face questions on Trump MFN deal, patent expiries and pipeline
AZN
Published: October 31, 2025 by: Proactive Investors
Sentiment: Neutral

When AstraZeneca PLC (LSE:AZN, NASDAQ:AZN) reports third-quarter results next Thursday, 6 November, with investors and analysts will be keen to hear about the financial implications of the 'most favoured nation' (MFN) pricing deal recently agreed with Donald Trump, as well as the loss of its Farxiga patent and prospects for new drugs coming out of its pipeline. This will be the first opportunity for discussion of the US MFN deal, making its a key discussion point, according to analysts at UBS.

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image for news AstraZeneca to face questions on Trump MFN deal, patent expiries and pipeline

About AstraZeneca PLC (AZN)

  • IPO Date 1993-05-12
  • Website https://www.astrazeneca.com
  • Industry Drug Manufacturers - General
  • CEO Pascal Claude Roland Soriot
  • Employees 94300

AstraZeneca PLC, a biopharmaceutical company, focuses on the discovery, development, manufacture, and commercialization of prescription medicines. The company's marketed products include Tagrisso, Imfinzi, Lynparza, Calquence, Enhertu, Orpathys, Truqap, Zoladex, Faslodex, Farxiga, Brilinta, Lokelma, Roxadustat, Andexxa, Crestor, Seloken, Onglyza, Bydureon, Fasenra, Breztri, Symbicort, Saphnelo, Tezspire, Pulmicort, Bevespi, and Daliresp for cardiovascular, renal, metabolism, and oncology. Its marketed products also comprise Vaxzevria, Beyfortus, Synagis, FluMist, Soliris, Ultomiris, Strensiq, Koselugo, and Kanuma for covid-19 and rare disease. The company serves primary care and specialty care physicians through distributors and local representative offices in the United Kingdom, rest of Europe, the Americas, Asia, Africa, and Australasia. It has a collaboration agreement with Neurimmune AG to develop and commercialize NI006; BenevolentAI for drug discovery for systemic lupus erythematosus; Lunit for developing AI-Powered Digital Pathology Risk Assessment Tools for NSCLC; and Absci Corporation for AI-driven drug discovery against an oncology target. The company was formerly known as Zeneca Group PLC and changed its name to AstraZeneca PLC in April 1999. AstraZeneca PLC was incorporated in 1992 and is headquartered in Cambridge, the United Kingdom.