Xilio Therapeutics, Inc. (XLO)

US — Healthcare Sector
Peers: CNTB  TYRA  RAPT  MLYS    EWTX  IKNA  DSGN  ELYM  ANEB  ANTX  AVTE  ADAG  MOLN  MNOV  CSBR  CYT 

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Key Metrics & Ratings

  • symbol XLO
  • Rev/Share 0.1241
  • Book/Share 0.1432
  • PB 4.6433
  • Debt/Equity 0.735
  • CurrentRatio 1.9565
  • ROIC -0.9932

 

  • MktCap 34440389.0
  • FreeCF/Share 0.2817
  • PFCF 1.6366
  • PE -1.2107
  • Debt/Assets 0.0758
  • DivYield 0
  • ROE -1.9852

 

  • Rating C
  • Score 2
  • Recommendation Sell
  • P/E Score 1
  • DCF Score 5
  • P/B Score 1
  • D/E Score 1

Recent Analyst Ratings

Type Ticker Analyst Firm Previous Rating Current Rating Previous Price Target Current Price Target Date
No ratings available.

News

Xilio Therapeutics Announces Pricing of $50.0 Million Public Offering
XLO
Published: June 02, 2025 by: GlobeNewsWire
Sentiment: Neutral

WALTHAM, Mass., June 02, 2025 (GLOBE NEWSWIRE) -- Xilio Therapeutics, Inc. (Nasdaq: XLO), a clinical-stage biotechnology company discovering and developing tumor-activated immuno-oncology therapies for people living with cancer, today announced the pricing of an underwritten public offering of pre-funded warrants to purchase 66,676,000 shares of common stock (the “pre-funded warrants”), accompanied by Series A warrants to purchase 66,676,000 shares of common stock (or, in certain circumstances, pre-funded warrants) (the “Series A warrants”), Series B warrants to purchase 66,676,000 shares of common stock (or, in certain circumstances, pre-funded warrants) (the “Series B warrants”) and Series C warrants to purchase 66,676,000 shares …

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image for news Xilio Therapeutics Announces Pricing of $50.0 Million Public Offering
Xilio Therapeutics Announces Proposed Public Offering
XLO
Published: June 02, 2025 by: GlobeNewsWire
Sentiment: Neutral

WALTHAM, Mass., June 02, 2025 (GLOBE NEWSWIRE) -- Xilio Therapeutics, Inc. (Nasdaq: XLO), a clinical-stage biotechnology company discovering and developing tumor-activated immuno-oncology therapies for people living with cancer, today announced that it is commencing an underwritten public offering of pre-funded warrants to purchase shares of common stock accompanied by Series A warrants to purchase shares of common stock (or, in certain circumstances, pre-funded warrants), Series B warrants to purchase shares of common stock (or, in certain circumstances, pre-funded warrants) and Series C warrants to purchase shares of common stock (or, in certain circumstances, pre-funded warrants). All of the securities to …

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image for news Xilio Therapeutics Announces Proposed Public Offering
Xilio Therapeutics Announces Pipeline and Business Updates and First Quarter 2025 Financial Results
XLO
Published: May 08, 2025 by: GlobeNewsWire
Sentiment: Neutral

Updated Phase 2 data to be presented at ASCO for vilastobart, a tumor-activated, Fc-enhanced, anti-CTLA-4, in combination with atezolizumab in patients with metastatic microsatellite stable colorectal cancer (MSS CRC) Advancing multiple masked T cell engager programs utilizing Xilio's novel ATACR and SEECR formats, with first development candidates anticipated in second half of 2025 WALTHAM, Mass., May 08, 2025 (GLOBE NEWSWIRE) -- Xilio Therapeutics, Inc. (Nasdaq: XLO), a clinical-stage biotechnology company discovering and developing tumor-activated immuno-oncology therapies for people living with cancer, today announced pipeline progress and business updates and reported financial results for the first quarter ended March 31, 2025.

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image for news Xilio Therapeutics Announces Pipeline and Business Updates and First Quarter 2025 Financial Results
Xilio Therapeutics, Inc. (XLO) Reports Q4 Loss, Lags Revenue Estimates
XLO
Published: March 11, 2025 by: Zacks Investment Research
Sentiment: Negative

Xilio Therapeutics, Inc. (XLO) came out with a quarterly loss of $0.20 per share versus the Zacks Consensus Estimate of a loss of $0.22. This compares to loss of $0.64 per share a year ago.

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image for news Xilio Therapeutics, Inc. (XLO) Reports Q4 Loss, Lags Revenue Estimates
Xilio Therapeutics to Present at TD Cowen 45th Annual Health Care Conference
XLO
Published: February 24, 2025 by: GlobeNewsWire
Sentiment: Neutral

WALTHAM, Mass., Feb. 24, 2025 (GLOBE NEWSWIRE) -- Xilio Therapeutics, Inc. (Nasdaq: XLO), a clinical-stage biotechnology company discovering and developing tumor-activated immuno-oncology therapies for people living with cancer, today announced that René Russo, Pharm.D., president and chief executive officer, will participate in a fireside chat at the TD Cowen 45th Annual Health Care Conference on Monday, March 3, 2025 at 9:50 am EST.

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image for news Xilio Therapeutics to Present at TD Cowen 45th Annual Health Care Conference
Xilio Therapeutics Announces Multiple Masked T Cell Engager Programs
XLO
Published: February 12, 2025 by: GlobeNewsWire
Sentiment: Neutral

Also entered into collaboration and option agreement with AbbVie to develop novel tumor-activated immunotherapies, including masked T cell engagers, with $52.0 million in upfront payments

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image for news Xilio Therapeutics Announces Multiple Masked T Cell Engager Programs
AbbVie and Xilio Therapeutics Announce Collaboration and Option Agreement to Develop Novel Tumor-Activated Immunotherapies
XLO
Published: February 12, 2025 by: GlobeNewsWire
Sentiment: Neutral

NORTH CHICAGO, Ill. and WALTHAM, Mass., Feb. 12, 2025 (GLOBE NEWSWIRE) -- AbbVie (NYSE: ABBV) and Xilio Therapeutics, Inc. (Nasdaq: XLO), a clinical-stage biotechnology company discovering and developing tumor-activated immuno-oncology therapies for people living with cancer, today announced a collaboration and option-to-license agreement to develop novel tumor-activated, antibody-based immunotherapies, including masked T-cell engagers, leveraging Xilio's proprietary technology.

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image for news AbbVie and Xilio Therapeutics Announce Collaboration and Option Agreement to Develop Novel Tumor-Activated Immunotherapies
AbbVie and Xilio Therapeutics Announce Collaboration and Option Agreement to Develop Novel Tumor-Activated Immunotherapies
ABBV, XLO
Published: February 12, 2025 by: PRNewsWire
Sentiment: Neutral

Collaboration will combine AbbVie's oncology expertise and Xilio's proprietary tumor-activation technology to develop novel immunotherapies, including masked T-cell engagers Xilio to host investor conference call and webcast today at 8:30 am EST NORTH CHICAGO, Ill. and WALTHAM, Mass.

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image for news AbbVie and Xilio Therapeutics Announce Collaboration and Option Agreement to Develop Novel Tumor-Activated Immunotherapies

About Xilio Therapeutics, Inc. (XLO)

  • IPO Date 2021-10-22
  • Website https://www.xiliotx.com
  • Industry Biotechnology
  • CEO Dr. Rene Russo BCPS, Pharm.D.
  • Employees 64

Xilio Therapeutics, Inc., a clinical-stage biotechnology company, develops immunotherapies to improve the immune system of cancer patients. Its checkpoint inhibitor program includes XTX101, a clinical-stage, tumor-selective anti-CTLA-4 mAb that is in Phase 1/2 clinical trials in patients with solid tumors. The company also develops cytokine programs, which comprises XTX202, a modified form of IL-2; XTX301, an IL-12 product candidate; and XTX401, an IL-15 product candidate that are masked with a protein domain to prevent binding activity until cleaved off by tumor microenvironment (TME)-associated proteases. Xilio Therapeutics, Inc. was founded in 2016 and is headquartered in Waltham, Massachusetts.