Vertex Pharmaceuticals Incorporated (VRTX)
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- symbol VRTX
- Rev/Share 47.4139
- Book/Share 73.5163
- PB 6.5429
- Debt/Equity 0.208
- CurrentRatio 2.9009
- ROIC 0.1625
- MktCap 122176540000.0
- FreeCF/Share 12.579
- PFCF 38.2543
- PE 30.8936
- Debt/Assets 0.1485
- DivYield 0
- ROE 0.227
- Rating A-
- Score 4
- Recommendation Buy
- P/E Score 2
- DCF Score 4
- P/B Score 1
- D/E Score 3
Recent Analyst Ratings
| Type | Ticker | Analyst Firm | Previous Rating | Current Rating | Previous Price Target | Current Price Target | Date |
|---|---|---|---|---|---|---|---|
| Upgrade | VRTX | Oppenheimer | Perform | Outperform | -- | $540 | Feb. 13, 2026 |
| Resumed | VRTX | Barclays | -- | Overweight | -- | $606 | Jan. 28, 2026 |
| Upgrade | VRTX | RBC Capital Mkts | Sector Perform | Outperform | -- | $546 | Jan. 22, 2026 |
| Upgrade | VRTX | Bernstein | Market Perform | Outperform | -- | -- | Jan. 12, 2026 |
| Resumed | VRTX | UBS | -- | Buy | -- | $535 | Jan. 7, 2026 |
| Upgrade | VRTX | Wolfe Research | Peer Perform | Outperform | -- | $548 | Jan. 6, 2026 |
| Upgrade | VRTX | Morgan Stanley | Equal Weight | Overweight | -- | $516 | Dec. 3, 2025 |
| Initiation | VRTX | Scotiabank | -- | Sector Outperform | -- | $495 | Nov. 13, 2025 |
| Upgrade | VRTX | Leerink Partners | Market Perform | Outperform | -- | $456 | Sept. 25, 2025 |
| Initiation | VRTX | Raymond James | -- | Market Perform | -- | -- | Sept. 3, 2025 |
News
Vertex Pharmaceuticals Stock: Is The Bull Run Over (Rating Downgrade)
Published: February 18, 2026 by: Seeking Alpha
Sentiment: Positive
I believe Vertex Pharmaceuticals Incorporated's bull run has come to an end. There's a divergence between its stock price growth over the past 5 months and the performance of Journavx and the cystic fibrosis franchise. So, in Q4, Trikafta+Kaftrio sales declined 3.1% quarter-on-quarter to about $2.57 billion, missing my "base case" scenario by $45 million.
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Here is What to Know Beyond Why Vertex Pharmaceuticals Incorporated (VRTX) is a Trending Stock
Published: February 17, 2026 by: Zacks Investment Research
Sentiment: Positive
Vertex (VRTX) has been one of the stocks most watched by Zacks.com users lately. So, it is worth exploring what lies ahead for the stock.
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VRTX's Q4 Earnings Miss Mark, Revenues Beat on Higher Product Sales
Published: February 13, 2026 by: Zacks Investment Research
Sentiment: Neutral
Vertex Q4 earnings miss estimates, but revenues top forecasts on strong CF sales and momentum from new launches like Alyftrek, Casgevy and Journavx.
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Why Vertex Pharmaceuticals (VRTX) is a Top Momentum Stock for the Long-Term
Published: February 12, 2026 by: Zacks Investment Research
Sentiment: Positive
The Zacks Style Scores offers investors a way to easily find top-rated stocks based on their investing style. Here's why you should take advantage.
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Vertex Gears Up to Report Q4 Earnings: Is a Beat in the Cards?
Published: February 10, 2026 by: Zacks Investment Research
Sentiment: Positive
VRTX is set to report Q4 results amid strong Trikafta demand. Alyftrek launches are gaining traction while investors are eyeing Casgevy and Journavx sales.
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Will These 5 Drug Bigwigs Surpass Q4 Earnings Forecasts?
Published: February 09, 2026 by: Zacks Investment Research
Sentiment: Positive
Let's look at five pharma and biotech companies, AZN, INCY, GILD, VRTX and MRNA, which are scheduled to release their fourth-quarter 2025 results this week.
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Vertex Q4 Earnings Preview: What To Expect This Week
Published: February 09, 2026 by: Seeking Alpha
Sentiment: Negative
Vertex Pharmaceuticals is downgraded to Hold ahead of Q4 earnings due to underwhelming growth from key new drugs. Journavx and Casgevy sales remain niche, raising doubts about their ability to drive the next growth phase already priced into consensus. 2026 sales guidance and Q4 Journavx performance are critical; failure to beat expectations may trigger downside risk.
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Seeking Clues to Vertex (VRTX) Q4 Earnings? A Peek Into Wall Street Projections for Key Metrics
Published: February 09, 2026 by: Zacks Investment Research
Sentiment: Neutral
Evaluate the expected performance of Vertex (VRTX) for the quarter ended December 2025, looking beyond the conventional Wall Street top-and-bottom-line estimates and examining some of its key metrics for better insight.
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Vertex Pharmaceuticals (VRTX) Earnings Expected to Grow: What to Know Ahead of Next Week's Release
Published: February 05, 2026 by: Zacks Investment Research
Sentiment: Positive
Vertex (VRTX) possesses the right combination of the two key ingredients for a likely earnings beat in its upcoming report. Get prepared with the key expectations.
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Why Investors Need to Take Advantage of These 2 Medical Stocks Now
Published: February 04, 2026 by: Zacks Investment Research
Sentiment: Positive
The Zacks Earnings ESP is a great way to find potential earnings surprises. Why investors should take advantage now.
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Is Trending Stock Vertex Pharmaceuticals Incorporated (VRTX) a Buy Now?
Published: February 03, 2026 by: Zacks Investment Research
Sentiment: Positive
Vertex (VRTX) has received quite a bit of attention from Zacks.com users lately. Therefore, it is wise to be aware of the facts that can impact the stock's prospects.
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WuXi Biologics and Vertex Sign License and Research Service Agreement for T-cell Engager
Published: February 02, 2026 by: PRNewsWire
Sentiment: Neutral
SHANGHAI, Feb. 2, 2026 /PRNewswire/ -- WuXi Biologics (2269. HK), a leading global Contract Research, Development, and Manufacturing Organization (CRDMO), today announced that it has signed a license and research service agreement with Vertex Pharmaceuticals Incorporated (Nasdaq: VRTX) for an innovative trispecific T-cell Engager (TCE) for the treatment of B-cell mediated autoimmune diseases.
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Wall Street Analysts Think Vertex (VRTX) Is a Good Investment: Is It?
Published: January 23, 2026 by: Zacks Investment Research
Sentiment: Neutral
The recommendations of Wall Street analysts are often relied on by investors when deciding whether to buy, sell, or hold a stock. Media reports about these brokerage-firm-employed (or sell-side) analysts changing their ratings often affect a stock's price.
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Will Vertex (VRTX) Beat Estimates Again in Its Next Earnings Report?
Published: January 12, 2026 by: Zacks Investment Research
Sentiment: Positive
Vertex (VRTX) has an impressive earnings surprise history and currently possesses the right combination of the two key ingredients for a likely beat in its next quarterly report.
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Vertex Pharmaceuticals Incorporated (VRTX) is Attracting Investor Attention: Here is What You Should Know
Published: January 07, 2026 by: Zacks Investment Research
Sentiment: Positive
Vertex (VRTX) has received quite a bit of attention from Zacks.com users lately. Therefore, it is wise to be aware of the facts that can impact the stock's prospects.
Read More
The Best Stocks to Invest $1,000 in to Start the New Year Off Right
Published: January 01, 2026 by: The Motley Fool
Sentiment: Positive
Alphabet should continue to benefit from a strong AI tailwind in 2026. Vertex Pharmaceuticals has several growth drivers in the new year.
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Here's Why Vertex Pharmaceuticals (VRTX) is a Strong Momentum Stock
Published: December 30, 2025 by: Zacks Investment Research
Sentiment: Positive
Wondering how to pick strong, market-beating stocks for your investment portfolio? Look no further than the Zacks Style Scores.
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Vertex Pharmaceuticals Incorporated (VRTX) Is a Trending Stock: Facts to Know Before Betting on It
Published: December 23, 2025 by: Zacks Investment Research
Sentiment: Positive
Recently, Zacks.com users have been paying close attention to Vertex (VRTX). This makes it worthwhile to examine what the stock has in store.
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Investors Heavily Search Vertex Pharmaceuticals Incorporated (VRTX): Here is What You Need to Know
Published: December 12, 2025 by: Zacks Investment Research
Sentiment: Positive
Vertex (VRTX) has received quite a bit of attention from Zacks.com users lately. Therefore, it is wise to be aware of the facts that can impact the stock's prospects.
Read More
Why Vertex Pharmaceuticals (VRTX) is a Top Momentum Stock for the Long-Term
Published: December 08, 2025 by: Zacks Investment Research
Sentiment: Positive
Wondering how to pick strong, market-beating stocks for your investment portfolio? Look no further than the Zacks Style Scores.
Read More
Why Is Vertex (VRTX) Up 2.7% Since Last Earnings Report?
Published: December 03, 2025 by: Zacks Investment Research
Sentiment: Positive
Vertex (VRTX) reported earnings 30 days ago. What's next for the stock?
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Vertex Pharmaceuticals Incorporated (VRTX) Presents at Citi Annual Global Healthcare Conference 2025 Transcript
Published: December 03, 2025 by: Seeking Alpha
Sentiment: Neutral
Vertex Pharmaceuticals Incorporated (VRTX) Presents at Citi Annual Global Healthcare Conference 2025 Transcript
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Vertex Up 9.2% in 3 Months: Should You Buy, Sell or Hold the Stock?
Published: December 03, 2025 by: Zacks Investment Research
Sentiment: Positive
VRTX rises 9.2% in three months but trails its industry as mixed new-drug sales and tightened 2025 guidance cloud near-term momentum.
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Here is What to Know Beyond Why Vertex Pharmaceuticals Incorporated (VRTX) is a Trending Stock
Published: December 01, 2025 by: Zacks Investment Research
Sentiment: Positive
Zacks.com users have recently been watching Vertex (VRTX) quite a bit. Thus, it is worth knowing the facts that could determine the stock's prospects.
Read More
Vertex Pharmaceuticals Incorporated (VRTX) is Attracting Investor Attention: Here is What You Should Know
Published: November 18, 2025 by: Zacks Investment Research
Sentiment: Positive
Vertex (VRTX) has received quite a bit of attention from Zacks.com users lately. Therefore, it is wise to be aware of the facts that can impact the stock's prospects.
Read More
Columbia Contrarian Core Fund Q3 2025 Performance Review
Published: November 18, 2025 by: Seeking Alpha
Sentiment: Negative
The fund underperformed its benchmark, the Russell 1000 Index, during the third quarter. Videogame producer Electronic Art's was the top contributor during the period. Elevance Health was the top underperformer over the period.
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3 Best Healthcare Stocks: Quant Strong Buys From Goldman's 'Alpha' List
Published: November 17, 2025 by: Seeking Alpha
Sentiment: Positive
The healthcare sector's renewed momentum offers fertile ground for investors wanting to outperform by picking the best stocks from the broader indexes. Goldman Sachs identified 29 healthcare stocks in the Russell 1000 universe with positive recent consensus revisions to 2026 EPS estimates and that trade at attractive valuations. Goldman sees "more opportunity for alpha than beta" as wide return dispersion and increasing M&A activity in healthcare may favor selected winners.
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Vertex Pharmaceuticals Incorporated (VRTX) Presents at UBS Global Healthcare Conference 2025 Transcript
Published: November 11, 2025 by: Seeking Alpha
Sentiment: Neutral
Vertex Pharmaceuticals Incorporated ( VRTX ) UBS Global Healthcare Conference 2025 November 11, 2025 10:15 AM EST Company Participants Reshma Kewalramani - CEO, President & Director Conference Call Participants Dina Elmonshed Presentation Dina Elmonshed Good morning, everyone. My name is Dina Elmonshed, one of the U.S. biotech analysts here at UBS.
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Vertex Pharmaceuticals Incorporated (VRTX) is Attracting Investor Attention: Here is What You Should Know
Published: November 07, 2025 by: Zacks Investment Research
Sentiment: Positive
Zacks.com users have recently been watching Vertex (VRTX) quite a bit. Thus, it is worth knowing the facts that could determine the stock's prospects.
Read More
VRTX's New Drugs Performance Mixed in Q3: Can Their Sales Improve?
Published: November 05, 2025 by: Zacks Investment Research
Sentiment: Positive
VRTX's new drugs deliver a mixed Q3 performance. Alyftrek sales surge.
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About Vertex Pharmaceuticals Incorporated (VRTX)
- IPO Date 1991-07-24
- Website https://www.vrtx.com
- Industry Biotechnology
- CEO Reshma Kewalramani
- Employees 6100