Vertex Pharmaceuticals Incorporated (VRTX)

US — Healthcare Sector
Peers: MCK  HCA  MDT  SNY  REGN  GSK  BMY  ARGX  CVS  SYK 

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Key Metrics & Ratings

  • symbol VRTX
  • Rev/Share 45.8658
  • Book/Share 67.7574
  • PB 6.8717
  • Debt/Equity 0.1059
  • CurrentRatio 2.3618
  • ROIC 0.1618

 

  • MktCap 119378051012.0
  • FreeCF/Share 13.0563
  • PFCF 35.7719
  • PE 32.3828
  • Debt/Assets 0.0738
  • DivYield 0
  • ROE 0.2181

 

  • Rating A-
  • Score 4
  • Recommendation Buy
  • P/E Score 2
  • DCF Score 4
  • P/B Score 1
  • D/E Score 3

Recent Analyst Ratings

Type Ticker Analyst Firm Previous Rating Current Rating Previous Price Target Current Price Target Date
Resumed VRTX Barclays -- Overweight -- $606 Jan. 28, 2026
Upgrade VRTX RBC Capital Mkts Sector Perform Outperform -- $546 Jan. 22, 2026
Upgrade VRTX Bernstein Market Perform Outperform -- -- Jan. 12, 2026
Resumed VRTX UBS -- Buy -- $535 Jan. 7, 2026
Upgrade VRTX Wolfe Research Peer Perform Outperform -- $548 Jan. 6, 2026
Upgrade VRTX Morgan Stanley Equal Weight Overweight -- $516 Dec. 3, 2025
Initiation VRTX Scotiabank -- Sector Outperform -- $495 Nov. 13, 2025
Upgrade VRTX Leerink Partners Market Perform Outperform -- $456 Sept. 25, 2025
Initiation VRTX Raymond James -- Market Perform -- -- Sept. 3, 2025
Upgrade VRTX Wells Fargo Equal Weight Overweight -- $460 Aug. 6, 2025

News

Why Investors Need to Take Advantage of These 2 Medical Stocks Now
INCY, VRTX
Published: February 04, 2026 by: Zacks Investment Research
Sentiment: Positive

The Zacks Earnings ESP is a great way to find potential earnings surprises. Why investors should take advantage now.

Read More
image for news Why Investors Need to Take Advantage of These 2 Medical Stocks Now
Is Trending Stock Vertex Pharmaceuticals Incorporated (VRTX) a Buy Now?
VRTX
Published: February 03, 2026 by: Zacks Investment Research
Sentiment: Positive

Vertex (VRTX) has received quite a bit of attention from Zacks.com users lately. Therefore, it is wise to be aware of the facts that can impact the stock's prospects.

Read More
image for news Is Trending Stock Vertex Pharmaceuticals Incorporated (VRTX) a Buy Now?
WuXi Biologics and Vertex Sign License and Research Service Agreement for T-cell Engager
VRTX
Published: February 02, 2026 by: PRNewsWire
Sentiment: Neutral

SHANGHAI, Feb. 2, 2026 /PRNewswire/ -- WuXi Biologics (2269. HK), a leading global Contract Research, Development, and Manufacturing Organization (CRDMO), today announced that it has signed a license and research service agreement with Vertex Pharmaceuticals Incorporated (Nasdaq: VRTX) for an innovative trispecific T-cell Engager (TCE) for the treatment of B-cell mediated autoimmune diseases.

Read More
image for news WuXi Biologics and Vertex Sign License and Research Service Agreement for T-cell Engager
Wall Street Analysts Think Vertex (VRTX) Is a Good Investment: Is It?
VRTX
Published: January 23, 2026 by: Zacks Investment Research
Sentiment: Neutral

The recommendations of Wall Street analysts are often relied on by investors when deciding whether to buy, sell, or hold a stock. Media reports about these brokerage-firm-employed (or sell-side) analysts changing their ratings often affect a stock's price.

Read More
image for news Wall Street Analysts Think Vertex (VRTX) Is a Good Investment: Is It?
Will Vertex (VRTX) Beat Estimates Again in Its Next Earnings Report?
VRTX
Published: January 12, 2026 by: Zacks Investment Research
Sentiment: Positive

Vertex (VRTX) has an impressive earnings surprise history and currently possesses the right combination of the two key ingredients for a likely beat in its next quarterly report.

Read More
image for news Will Vertex (VRTX) Beat Estimates Again in Its Next Earnings Report?
Vertex Pharmaceuticals Incorporated (VRTX) is Attracting Investor Attention: Here is What You Should Know
VRTX
Published: January 07, 2026 by: Zacks Investment Research
Sentiment: Positive

Vertex (VRTX) has received quite a bit of attention from Zacks.com users lately. Therefore, it is wise to be aware of the facts that can impact the stock's prospects.

Read More
image for news Vertex Pharmaceuticals Incorporated (VRTX) is Attracting Investor Attention: Here is What You Should Know
The Best Stocks to Invest $1,000 in to Start the New Year Off Right
ENB, GOOG, GOOGL, VRTX
Published: January 01, 2026 by: The Motley Fool
Sentiment: Positive

Alphabet should continue to benefit from a strong AI tailwind in 2026. Vertex Pharmaceuticals has several growth drivers in the new year.

Read More
image for news The Best Stocks to Invest $1,000 in to Start the New Year Off Right
Here's Why Vertex Pharmaceuticals (VRTX) is a Strong Momentum Stock
VRTX
Published: December 30, 2025 by: Zacks Investment Research
Sentiment: Positive

Wondering how to pick strong, market-beating stocks for your investment portfolio? Look no further than the Zacks Style Scores.

Read More
image for news Here's Why Vertex Pharmaceuticals (VRTX) is a Strong Momentum Stock
Vertex Pharmaceuticals Incorporated (VRTX) Is a Trending Stock: Facts to Know Before Betting on It
VRTX
Published: December 23, 2025 by: Zacks Investment Research
Sentiment: Positive

Recently, Zacks.com users have been paying close attention to Vertex (VRTX). This makes it worthwhile to examine what the stock has in store.

Read More
image for news Vertex Pharmaceuticals Incorporated (VRTX) Is a Trending Stock: Facts to Know Before Betting on It
Investors Heavily Search Vertex Pharmaceuticals Incorporated (VRTX): Here is What You Need to Know
VRTX
Published: December 12, 2025 by: Zacks Investment Research
Sentiment: Positive

Vertex (VRTX) has received quite a bit of attention from Zacks.com users lately. Therefore, it is wise to be aware of the facts that can impact the stock's prospects.

Read More
image for news Investors Heavily Search Vertex Pharmaceuticals Incorporated (VRTX): Here is What You Need to Know
Why Vertex Pharmaceuticals (VRTX) is a Top Momentum Stock for the Long-Term
VRTX
Published: December 08, 2025 by: Zacks Investment Research
Sentiment: Positive

Wondering how to pick strong, market-beating stocks for your investment portfolio? Look no further than the Zacks Style Scores.

Read More
image for news Why Vertex Pharmaceuticals (VRTX) is a Top Momentum Stock for the Long-Term
Why Is Vertex (VRTX) Up 2.7% Since Last Earnings Report?
VRTX
Published: December 03, 2025 by: Zacks Investment Research
Sentiment: Positive

Vertex (VRTX) reported earnings 30 days ago. What's next for the stock?

Read More
image for news Why Is Vertex (VRTX) Up 2.7% Since Last Earnings Report?
Vertex Pharmaceuticals Incorporated (VRTX) Presents at Citi Annual Global Healthcare Conference 2025 Transcript
VRTX
Published: December 03, 2025 by: Seeking Alpha
Sentiment: Neutral

Vertex Pharmaceuticals Incorporated (VRTX) Presents at Citi Annual Global Healthcare Conference 2025 Transcript

Read More
image for news Vertex Pharmaceuticals Incorporated (VRTX) Presents at Citi Annual Global Healthcare Conference 2025 Transcript
Vertex Up 9.2% in 3 Months: Should You Buy, Sell or Hold the Stock?
VRTX
Published: December 03, 2025 by: Zacks Investment Research
Sentiment: Positive

VRTX rises 9.2% in three months but trails its industry as mixed new-drug sales and tightened 2025 guidance cloud near-term momentum.

Read More
image for news Vertex Up 9.2% in 3 Months: Should You Buy, Sell or Hold the Stock?
Here is What to Know Beyond Why Vertex Pharmaceuticals Incorporated (VRTX) is a Trending Stock
VRTX
Published: December 01, 2025 by: Zacks Investment Research
Sentiment: Positive

Zacks.com users have recently been watching Vertex (VRTX) quite a bit. Thus, it is worth knowing the facts that could determine the stock's prospects.

Read More
image for news Here is What to Know Beyond Why Vertex Pharmaceuticals Incorporated (VRTX) is a Trending Stock
Vertex Pharmaceuticals Incorporated (VRTX) is Attracting Investor Attention: Here is What You Should Know
VRTX
Published: November 18, 2025 by: Zacks Investment Research
Sentiment: Positive

Vertex (VRTX) has received quite a bit of attention from Zacks.com users lately. Therefore, it is wise to be aware of the facts that can impact the stock's prospects.

Read More
image for news Vertex Pharmaceuticals Incorporated (VRTX) is Attracting Investor Attention: Here is What You Should Know
Columbia Contrarian Core Fund Q3 2025 Performance Review
EA, EBAY, ELV, INTU, TEL, VRTX
Published: November 18, 2025 by: Seeking Alpha
Sentiment: Negative

The fund underperformed its benchmark, the Russell 1000 Index, during the third quarter. Videogame producer Electronic Art's was the top contributor during the period. Elevance Health was the top underperformer over the period.

Read More
image for news Columbia Contrarian Core Fund Q3 2025 Performance Review
3 Best Healthcare Stocks: Quant Strong Buys From Goldman's 'Alpha' List
INCY, PFE, PPH, VRTX, XBI, XLV
Published: November 17, 2025 by: Seeking Alpha
Sentiment: Positive

The healthcare sector's renewed momentum offers fertile ground for investors wanting to outperform by picking the best stocks from the broader indexes. Goldman Sachs identified 29 healthcare stocks in the Russell 1000 universe with positive recent consensus revisions to 2026 EPS estimates and that trade at attractive valuations. Goldman sees "more opportunity for alpha than beta" as wide return dispersion and increasing M&A activity in healthcare may favor selected winners.

Read More
image for news 3 Best Healthcare Stocks: Quant Strong Buys From Goldman's 'Alpha' List
Vertex Pharmaceuticals Incorporated (VRTX) Presents at UBS Global Healthcare Conference 2025 Transcript
VRTX
Published: November 11, 2025 by: Seeking Alpha
Sentiment: Neutral

Vertex Pharmaceuticals Incorporated ( VRTX ) UBS Global Healthcare Conference 2025 November 11, 2025 10:15 AM EST Company Participants Reshma Kewalramani - CEO, President & Director Conference Call Participants Dina Elmonshed Presentation Dina Elmonshed Good morning, everyone. My name is Dina Elmonshed, one of the U.S. biotech analysts here at UBS.

Read More
image for news Vertex Pharmaceuticals Incorporated (VRTX) Presents at UBS Global Healthcare Conference 2025 Transcript
Vertex Pharmaceuticals Incorporated (VRTX) is Attracting Investor Attention: Here is What You Should Know
VRTX
Published: November 07, 2025 by: Zacks Investment Research
Sentiment: Positive

Zacks.com users have recently been watching Vertex (VRTX) quite a bit. Thus, it is worth knowing the facts that could determine the stock's prospects.

Read More
image for news Vertex Pharmaceuticals Incorporated (VRTX) is Attracting Investor Attention: Here is What You Should Know
VRTX's New Drugs Performance Mixed in Q3: Can Their Sales Improve?
VRTX
Published: November 05, 2025 by: Zacks Investment Research
Sentiment: Positive

VRTX's new drugs deliver a mixed Q3 performance. Alyftrek sales surge.

Read More
image for news VRTX's New Drugs Performance Mixed in Q3: Can Their Sales Improve?
Committee stocks on the move: Uber and Vertex Pharma
UBER, VRTX
Published: November 04, 2025 by: CNBC Television
Sentiment: Neutral

The Investment Committee discuss some of their stocks on the move today.

Read More
image for news Committee stocks on the move: Uber and Vertex Pharma
Vertex Q3 Earnings Beat, Stock Down as Casgevy Sales Disappoint
VRTX
Published: November 04, 2025 by: Zacks Investment Research
Sentiment: Neutral

VRTX tops Q3 earnings and revenue estimates on strong Trikafta and Alyftrek sales, but shares slip as Casgevy sales disappoint.

Read More
image for news Vertex Q3 Earnings Beat, Stock Down as Casgevy Sales Disappoint
Vertex Pharmaceuticals Likely To Report Higher Q3 Earnings; These Most Accurate Analysts Revise Forecasts Ahead Of Earnings Call
VRTX
Published: November 03, 2025 by: Benzinga
Sentiment: Positive

Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) will release earnings results for the first quarter, after the closing bell on Monday, Nov. 3.

Read More
image for news Vertex Pharmaceuticals Likely To Report Higher Q3 Earnings; These Most Accurate Analysts Revise Forecasts Ahead Of Earnings Call
Vertex Gears Up to Report Q3 Earnings: Is a Beat in the Cards?
VRTX
Published: October 28, 2025 by: Zacks Investment Research
Sentiment: Positive

Strong Trikafta/Kaftrio demand, along with contributions from Alyftrek, Casgevy and Journavx, may have helped VRTX outperform in the third quarter.

Read More
image for news Vertex Gears Up to Report Q3 Earnings: Is a Beat in the Cards?
Vertex Pharmaceuticals (VRTX) Earnings Expected to Grow: Should You Buy?
VRTX
Published: October 27, 2025 by: Zacks Investment Research
Sentiment: Positive

Vertex (VRTX) possesses the right combination of the two key ingredients for a likely earnings beat in its upcoming report. Get prepared with the key expectations.

Read More
image for news Vertex Pharmaceuticals (VRTX) Earnings Expected to Grow: Should You Buy?
Vertex Pharmaceuticals Incorporated (VRTX) Is a Trending Stock: Facts to Know Before Betting on It
VRTX
Published: October 22, 2025 by: Zacks Investment Research
Sentiment: Positive

Recently, Zacks.com users have been paying close attention to Vertex (VRTX). This makes it worthwhile to examine what the stock has in store.

Read More
image for news Vertex Pharmaceuticals Incorporated (VRTX) Is a Trending Stock: Facts to Know Before Betting on It
Vertex Announces Progress in Povetacicept Development Program and Presentation of New Data at American Society of Nephrology Kidney Week
VRTX
Published: October 17, 2025 by: Business Wire
Sentiment: Neutral

BOSTON--(BUSINESS WIRE)--Vertex Pharmaceuticals Incorporated (Nasdaq: VRTX) today announced several important updates across its development program for povetacicept (pove), an investigational recombinant fusion protein therapeutic and dual antagonist of the BAFF (B cell activating factor) and APRIL (a proliferation inducing ligand) cytokines. Pove has demonstrated best-in-class potential in IgA nephropathy (IgAN) and primary membranous nephropathy (pMN) and has pipeline-in-a-product potential.

Read More
image for news Vertex Announces Progress in Povetacicept Development Program and Presentation of New Data at American Society of Nephrology Kidney Week
Investors Heavily Search Vertex Pharmaceuticals Incorporated (VRTX): Here is What You Need to Know
VRTX
Published: October 08, 2025 by: Zacks Investment Research
Sentiment: Positive

Vertex (VRTX) has received quite a bit of attention from Zacks.com users lately. Therefore, it is wise to be aware of the facts that can impact the stock's prospects.

Read More
image for news Investors Heavily Search Vertex Pharmaceuticals Incorporated (VRTX): Here is What You Need to Know
Why Investors Need to Take Advantage of These 2 Medical Stocks Now
MRNA, VRTX
Published: October 06, 2025 by: Zacks Investment Research
Sentiment: Positive

Investors looking for ways to find stocks that are set to beat quarterly earnings estimates should check out the Zacks Earnings ESP.

Read More
image for news Why Investors Need to Take Advantage of These 2 Medical Stocks Now

About Vertex Pharmaceuticals Incorporated (VRTX)

  • IPO Date 1991-07-24
  • Website https://www.vrtx.com
  • Industry Biotechnology
  • CEO Reshma Kewalramani
  • Employees 6100

Vertex Pharmaceuticals Incorporated, a biotechnology company, engages in developing and commercializing therapies for treating cystic fibrosis. The company markets SYMDEKO/SYMKEVI, ORKAMBI, and KALYDECO to treat patients with cystic fibrosis who have specific mutations in their cystic fibrosis transmembrane conductance regulator gene; and TRIKAFTA for the treatment of patients with CF 6 years of age or older who have at least one F508del mutation. Its pipeline includes VX-864 for the treatment of AAT deficiency, which is in Phase 2 clinical trial; VX-147 for the treatment of APOL1-mediated focal segmental glomerulosclerosis, or FSGS, and other serious kidney diseases which is in Phase 2 clinical trial; VX- 880, treatment for Type 1 Diabetes which is in Phase 1/2 clinical trial; VX-548, a NaV1.8 inhibitor for treatments of acute, neuropathic, musculoskeletal pain which is in Phase 2 clinical trial; and CTX001 for the treatment severe SCD and TDT which is in Phase 3 clinical trial. The company sells its products primarily to specialty pharmacy and specialty distributors in the United States, as well as specialty distributors and retail chains, and hospitals and clinics internationally. It has collaborations with Affinia Therapeutics, Inc.; Arbor Biotechnologies, Inc.; CRISPR Therapeutics AG.; Kymera Therapeutics, Inc.; Mammoth Biosciences, Inc.; Moderna, Inc.; Obsidian Therapeutics, Inc.; and Skyhawk Therapeutics, Inc.; as well as Ribometrix, Inc.; Genomics plc; Merck KGaA; Darmstadt, Germany, and X-Chem, Inc. Vertex Pharmaceuticals Incorporated was founded in 1989 and is headquartered in Boston, Massachusetts.