Vertex Pharmaceuticals Incorporated (VRTX)

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Key Metrics & Ratings

  • symbol VRTX
  • Rev/Share 43.2063
  • Book/Share 64.2129
  • PB 6.8841
  • Debt/Equity 0.1
  • CurrentRatio 2.6456
  • ROIC -0.128

 

  • MktCap 113517113850.0
  • FreeCF/Share -4.8968
  • PFCF -90.2362
  • PE -114.8373
  • Debt/Assets 0.0721
  • DivYield 0
  • ROE -0.0625

 

  • Rating C
  • Score 2
  • Recommendation Sell
  • P/E Score 1
  • DCF Score 4
  • P/B Score 1
  • D/E Score 3

Recent Analyst Ratings

Type Ticker Analyst Firm Previous Rating Current Rating Previous Price Target Current Price Target Date
Downgrade VRTX Wolfe Research Outperform Peer Perform -- -- May 7, 2025
Downgrade VRTX Leerink Partners Outperform Market Perform -- $503 May 6, 2025
Resumed VRTX Cantor Fitzgerald -- Overweight -- $535 April 22, 2025
Upgrade VRTX Canaccord Genuity Sell Hold $408 $424 Feb. 12, 2025
Upgrade VRTX Canaccord Genuity Sell Hold -- -- Feb. 11, 2025
Downgrade VRTX Wells Fargo Overweight Equal Weight -- $460 Jan. 30, 2025
Reiterated VRTX H.C. Wainwright -- Buy $600 $535 Dec. 20, 2024
Downgrade VRTX Oppenheimer Outperform Perform -- -- Dec. 19, 2024
Upgrade VRTX Jefferies Hold Buy $500 $550 Dec. 9, 2024
Initiation VRTX Scotiabank -- Sector Perform -- -- Oct. 16, 2024

News

Vertex Pharmaceuticals Incorporated (VRTX) Bernstein 41st Annual Strategic Decisions Conference (Transcript)
VRTX
Published: May 30, 2025 by: Seeking Alpha
Sentiment: Neutral

Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX ) Bernstein 41st Annual Strategic Decisions Conference May 30, 2025 8:00 AM ET Company Participants Reshma Kewalramani - President & CEO Conference Call Participants Will Pickering - Bernstein Will Pickering All right. Well, I think we can get started.

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image for news Vertex Pharmaceuticals Incorporated (VRTX) Bernstein 41st Annual Strategic Decisions Conference (Transcript)
3 Top Growth Stocks to Buy in the Second Half of 2025
AMZN, META, VRTX
Published: May 26, 2025 by: The Motley Fool
Sentiment: Positive

Believe it or not, but we're not far away from being halfway through the year. Time flies when you're having fun -- and when you're not having fun, too.

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image for news 3 Top Growth Stocks to Buy in the Second Half of 2025
Vertex: Continuing To Dominate In CF, But What About Its Pain Pipeline?
VRTX
Published: May 23, 2025 by: Seeking Alpha
Sentiment: Positive

Vertex Pharmaceuticals Incorporated remains a buy despite recent share price weakness, supported by its dominant cystic fibrosis franchise and robust late-stage pipeline. Alyftrek's launch extends Vertex's CF leadership, patent life, and addressable market, while Casgevy and Journavx add new growth avenues. VRTX valuation is justified by stable CF cash flows, a strong balance sheet, proven management, and a diversified pipeline with multiple near-term catalysts.

Read More
image for news Vertex: Continuing To Dominate In CF, But What About Its Pain Pipeline?
Final Trades: Vertex Pharma, Palantir, Wynn Resorts and Microsoft
MSFT, PLTR, VRTX, WYNN
Published: May 09, 2025 by: CNBC Television
Sentiment: Neutral

The Investment Committee give you their top names to watch for the second half.

Read More
image for news Final Trades: Vertex Pharma, Palantir, Wynn Resorts and Microsoft
Vertex Pharmaceuticals Incorporated (VRTX) is Attracting Investor Attention: Here is What You Should Know
VRTX
Published: May 09, 2025 by: Zacks Investment Research
Sentiment: Positive

Recently, Zacks.com users have been paying close attention to Vertex (VRTX). This makes it worthwhile to examine what the stock has in store.

Read More
image for news Vertex Pharmaceuticals Incorporated (VRTX) is Attracting Investor Attention: Here is What You Should Know
VRTX Stock Down as Q1 Sales of New Drugs Miss Expectations
VRTX
Published: May 07, 2025 by: Zacks Investment Research
Sentiment: Negative

Sales from VRTX's new drugs, Casgevy, Alyftrek and Journavx, in Q1 fell short of investor expectations.

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image for news VRTX Stock Down as Q1 Sales of New Drugs Miss Expectations
Vertex On Track To Significantly Improve Revenue And Earnings By 2030
VRTX
Published: May 06, 2025 by: Seeking Alpha
Sentiment: Positive

Vertex Pharmaceuticals reported decent Q1 earnings, but the company missed estimates for both revenue and earnings. Vertex's diversification efforts are most visible in the progress of its pain management portfolio. The FDA approval of Journavx marks the beginning of a new era for the company. VRTX is not going to be the same company by 2030. I expect notable changes in its margin profile as the company diversifies into new markets.

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image for news Vertex On Track To Significantly Improve Revenue And Earnings By 2030
Why Did Vertex Pharmaceuticals Stock Fall On Tuesday?
VRTX
Published: May 06, 2025 by: Benzinga
Sentiment: Negative

On Monday, Vertex Pharmaceuticals Incorporated VRTX reported lower-than-expected first-quarter 2025 earnings.

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image for news Why Did Vertex Pharmaceuticals Stock Fall On Tuesday?
VRTX's Q1 Earnings Lag Estimates, 2025 Revenue View Tightened
VRTX
Published: May 06, 2025 by: Zacks Investment Research
Sentiment: Negative

Vertex reports weaker-than-expected first-quarter 2025 results. The company tightens its total revenue guidance for 2025.

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image for news VRTX's Q1 Earnings Lag Estimates, 2025 Revenue View Tightened
Vertex Pharmaceuticals Stock Is Tumbling After Earnings. Here's Why.
VRTX
Published: May 06, 2025 by: Barrons
Sentiment: Negative

The company discloses narrower-than-expected access to its new painkiller.

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image for news Vertex Pharmaceuticals Stock Is Tumbling After Earnings. Here's Why.
Top Stock Movers Now: Vertex, DoorDash, Constellation Energy, and More
CEG, DASH, VRTX
Published: May 06, 2025 by: Investopedia
Sentiment: Negative

U.S. equities were lower at midday as the market watched for any possible deals involving Trump administration tariffs and awaited tomorrow's statement from the Federal Reserve policymakers following their two-day meeting. The Dow Jones Industrial Average, S&P 500, and Nasdaq all fell.

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image for news Top Stock Movers Now: Vertex, DoorDash, Constellation Energy, and More
2 Pharma Stocks Staging Big Post-Earnings Moves
NBIX, VRTX
Published: May 06, 2025 by: Schaeffers Research
Sentiment: Neutral

Biopharmaceutical giants Vertex Pharmaceuticals Inc (NASDAQ:VRTX) and Neurocrine Biosciences Inc (NASDAQ:NBIX) are fresh out of the earnings confessional, with very different results.

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image for news 2 Pharma Stocks Staging Big Post-Earnings Moves
Why Vertex Pharmaceuticals Stock Is Sinking Today
VRTX
Published: May 06, 2025 by: The Motley Fool
Sentiment: Negative

Shares of Vertex Pharmaceuticals (VRTX -11.69%) were sinking 11.9% as of 10:18 a.m. ET on Tuesday.

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image for news Why Vertex Pharmaceuticals Stock Is Sinking Today
Rising Costs Weigh on Vertex Q1 Earnings
VRTX
Published: May 06, 2025 by: The Motley Fool
Sentiment: Neutral

Here's our initial take on Vertex Pharmaceuticals' (VRTX -0.27%) first-quarter financial report.

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image for news Rising Costs Weigh on Vertex Q1 Earnings
Vertex: Improved Outlook Despite First Quarter Miss (Rating Upgrade)
VRTX
Published: May 06, 2025 by: Seeking Alpha
Sentiment: Positive

Vertex Pharmaceuticals missed Q1 revenue and EPS estimates but this is not a cause for concern as the full-year outlook has improved. Alyftrek is off to a good start and early launch metrics of Journavx look promising. Casgevy's progress is slow but uptake should improve going forward.

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image for news Vertex: Improved Outlook Despite First Quarter Miss (Rating Upgrade)
Final Trades: Berkshire Hathaway, Vertex Pharma, S&P Global and CME Group
BRK-A, BRK-B, CME, VRTX
Published: April 30, 2025 by: CNBC Television
Sentiment: Neutral

Final Trades are in! The Investment Committee reveals their top picks to close out the day—don't miss it!

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image for news Final Trades: Berkshire Hathaway, Vertex Pharma, S&P Global and CME Group
What Analyst Projections for Key Metrics Reveal About Vertex (VRTX) Q1 Earnings
VRTX
Published: April 30, 2025 by: Zacks Investment Research
Sentiment: Positive

Looking beyond Wall Street's top -and-bottom-line estimate forecasts for Vertex (VRTX), delve into some of its key metrics to gain a deeper insight into the company's potential performance for the quarter ended March 2025.

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image for news What Analyst Projections for Key Metrics Reveal About Vertex (VRTX) Q1 Earnings
Baron Health Care Fund Q1 2025 Top Contributors And Detractors
ACLX, BSX, DHR, GKOS, INSM, ISRG, LLY, RDNT, UNH, VRTX
Published: April 29, 2025 by: Seeking Alpha
Sentiment: Positive

Boston Scientific's shares rose due to strong market growth, innovative products like pulsed field ablation, and disciplined cost management, driving double-digit EPS growth. Vertex Pharmaceuticals saw increased investor confidence in its cystic fibrosis franchise and evolving pipeline, including promising non-opioid pain treatments and kidney disease drugs. UnitedHealth Group's shares gained as 2024 headwinds subsided, Medicare Advantage rates improved, and higher-margin Optum segments grew, insulating it from tariff impacts.

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image for news Baron Health Care Fund Q1 2025 Top Contributors And Detractors
My 5 Top Stocks to Buy Right Now in This Highly Volatile Market
BRK-A, BRK-B, D, EPD, PFE, VRTX
Published: April 28, 2025 by: The Motley Fool
Sentiment: Positive

Getting dizzy from the stock market's gyrations? Join the club.

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image for news My 5 Top Stocks to Buy Right Now in This Highly Volatile Market
Vertex Pharmaceuticals Incorporated (VRTX) Is a Trending Stock: Facts to Know Before Betting on It
VRTX
Published: April 23, 2025 by: Zacks Investment Research
Sentiment: Positive

Vertex (VRTX) has been one of the stocks most watched by Zacks.com users lately. So, it is worth exploring what lies ahead for the stock.

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image for news Vertex Pharmaceuticals Incorporated (VRTX) Is a Trending Stock: Facts to Know Before Betting on It
Why Investors Need to Take Advantage of These 2 Medical Stocks Now
CAH, VRTX
Published: April 22, 2025 by: Zacks Investment Research
Sentiment: Positive

The Zacks Earnings ESP is a great way to find potential earnings surprises. Why investors should take advantage now.

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image for news Why Investors Need to Take Advantage of These 2 Medical Stocks Now
3 Relatively Safe Healthcare Growth Stocks You Can Buy and Hold
AMGN, LLY, VRTX
Published: April 22, 2025 by: The Motley Fool
Sentiment: Positive

When the stock market is highly volatile, many investors flock to assets that offer stability but dismal growth prospects. However, you don't necessarily have to sacrifice growth for safety.

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image for news 3 Relatively Safe Healthcare Growth Stocks You Can Buy and Hold
Fed Chairman Jerome Powell Warns Trump's Tariffs Could Cause Stagflation: 3 Stocks to Buy and Hold if He's Right
D, KR, VRTX
Published: April 22, 2025 by: The Motley Fool
Sentiment: Negative

President Trump isn't a fan of Fed Chairman Jerome Powell, despite nominating Powell to replace Janet Yellen in 2017. Trump recently called Powell a "major loser" on a social media post and demanded that he lower interest rates immediately.

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image for news Fed Chairman Jerome Powell Warns Trump's Tariffs Could Cause Stagflation: 3 Stocks to Buy and Hold if He's Right
Final Trades: Vertex, Robinhood, Palo Alto and Crowdstrike
CRWD, HOOD, PANW, VRTX
Published: April 10, 2025 by: CNBC Television
Sentiment: Neutral

The Investment Committee give you their top stocks to watch in this volatile markets.

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image for news Final Trades: Vertex, Robinhood, Palo Alto and Crowdstrike
Investors Heavily Search Vertex Pharmaceuticals Incorporated (VRTX): Here is What You Need to Know
VRTX
Published: April 09, 2025 by: Zacks Investment Research
Sentiment: Positive

Recently, Zacks.com users have been paying close attention to Vertex (VRTX). This makes it worthwhile to examine what the stock has in store.

Read More
image for news Investors Heavily Search Vertex Pharmaceuticals Incorporated (VRTX): Here is What You Need to Know
Corporate CFOs Think a Recession Is Coming. Here Are 3 Stocks to Own If They're Right.
D, VRTX, WMT
Published: April 04, 2025 by: The Motley Fool
Sentiment: Neutral

Which group of individuals is in the best position to spot early warning signs of economic trouble? There's a good case to be made for corporate chief financial officers (CFOs).

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image for news Corporate CFOs Think a Recession Is Coming. Here Are 3 Stocks to Own If They're Right.
Vertex Pharmaceuticals (VRTX) Increases Despite Market Slip: Here's What You Need to Know
VRTX
Published: April 03, 2025 by: Zacks Investment Research
Sentiment: Negative

Vertex Pharmaceuticals (VRTX) reachead $484.01 at the closing of the latest trading day, reflecting a +0.11% change compared to its last close.

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image for news Vertex Pharmaceuticals (VRTX) Increases Despite Market Slip: Here's What You Need to Know
Trump's tariffs are a new challenge for Big Pharma. Here are the best positioned stocks
ABBV, AMGN, BMY, GILD, LLY, MRK, MRNA, PFE, VRTX
Published: April 01, 2025 by: CNBC
Sentiment: Negative

Leerink Partners analyst David Resinger warned his clients on Sunday that the tariff risks to the industry are 'underappreciated.'

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image for news Trump's tariffs are a new challenge for Big Pharma. Here are the best positioned stocks
VRTX Provides Mixed Updates for Type 1 Diabetes Pipeline Candidates
VRTX
Published: April 01, 2025 by: Zacks Investment Research
Sentiment: Positive

Vertex plans to submit regulatory filings seeking approval for zimislecel in type 1 diabetes in 2026. However, it is likely to stop further development of VX-264.

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image for news VRTX Provides Mixed Updates for Type 1 Diabetes Pipeline Candidates
Biopharma firms with foreign exposure face disruption as Trump's tariffs loom
AMGN, BIIB, GILD, VRTX
Published: March 27, 2025 by: Proactive Investors
Sentiment: Negative

The biopharmaceutical industry is bracing for potential disruptions from proposed tariffs aimed at encouraging companies to move manufacturing operations back to the United States. This week, president Donald Trump suggested that tariffs could be implemented on pharma products made outside the US, with a particular focus on Ireland, where many biopharma companies benefit from favorable tax conditions.

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image for news Biopharma firms with foreign exposure face disruption as Trump's tariffs loom

About Vertex Pharmaceuticals Incorporated (VRTX)

  • IPO Date 1991-07-24
  • Website https://www.vrtx.com
  • Industry Biotechnology
  • CEO Dr. Reshma Kewalramani FASN, M.D.
  • Employees 6100

Vertex Pharmaceuticals Incorporated, a biotechnology company, engages in developing and commercializing therapies for treating cystic fibrosis. The company markets SYMDEKO/SYMKEVI, ORKAMBI, and KALYDECO to treat patients with cystic fibrosis who have specific mutations in their cystic fibrosis transmembrane conductance regulator gene; and TRIKAFTA for the treatment of patients with CF 6 years of age or older who have at least one F508del mutation. Its pipeline includes VX-864 for the treatment of AAT deficiency, which is in Phase 2 clinical trial; VX-147 for the treatment of APOL1-mediated focal segmental glomerulosclerosis, or FSGS, and other serious kidney diseases which is in Phase 2 clinical trial; VX- 880, treatment for Type 1 Diabetes which is in Phase 1/2 clinical trial; VX-548, a NaV1.8 inhibitor for treatments of acute, neuropathic, musculoskeletal pain which is in Phase 2 clinical trial; and CTX001 for the treatment severe SCD and TDT which is in Phase 3 clinical trial. The company sells its products primarily to specialty pharmacy and specialty distributors in the United States, as well as specialty distributors and retail chains, and hospitals and clinics internationally. It has collaborations with Affinia Therapeutics, Inc.; Arbor Biotechnologies, Inc.; CRISPR Therapeutics AG.; Kymera Therapeutics, Inc.; Mammoth Biosciences, Inc.; Moderna, Inc.; Obsidian Therapeutics, Inc.; and Skyhawk Therapeutics, Inc.; as well as Ribometrix, Inc.; Genomics plc; Merck KGaA; Darmstadt, Germany, and X-Chem, Inc. Vertex Pharmaceuticals Incorporated was founded in 1989 and is headquartered in Boston, Massachusetts.