SPTX

Seaport Therapeutics, Inc. Common Stock
NASDAQHEALTHCAREBIOTECHNOLOGY

Key Statistics

Market Cap
$1.09B
P/E Ratio
—
EPS
$-4.35
Beta
—
52W High
$28.38
52W Low
$14.85
50-Day MA
$20.92
200-Day MA
$20.14
Dividend Yield
—
Profit Margin
0.00%
Forward P/E
—
PEG Ratio
—

About Seaport Therapeutics, Inc. Common Stock

Seaport Therapeutics, Inc. (SPTX) is a pioneering biopharmaceutical firm dedicated to advancing cutting-edge immune-oncology therapies to meet critical unmet medical needs, particularly in the field of oncology. The company leverages innovative technologies and a robust research pipeline to develop targeted treatment solutions for complex diseases, with a strong focus on cancer. Supported by strategic collaborations and an experienced management team, Seaport Therapeutics is well-positioned to drive scientific advancements that enhance patient outcomes and reshape the landscape of cancer treatment and immunotherapy.

Official WebsiteUSAFY End: December

Fundamentals

Revenue (TTM)0
Gross Profit (TTM)0
EBITDA$-148.66M
Operating Margin0.00%
Return on Equity-28.10%
Return on Assets-18.90%
Revenue/Share (TTM)$0.00
Book Value$7.42
Price-to-Book2.82
Price-to-Sales (TTM)—
EV/Revenue-
EV/EBITDA—
Quarterly Earnings Growth (YoY)0.00%
Quarterly Revenue Growth (YoY)0.00%
Shares Outstanding$53.53M
Float$18.43M
% Insiders35.14%
% Institutions70.93%

Historical Volatility

HV 10-Day
63.40%
HV 20-Day
67.65%
HV 30-Day
73.66%
HV 60-Day
73.45%
HV Rank
—

Volatility is currently contracting

Analyst Ratings

Consensus ($37.00 target)
1
Strong Buy
7
Buy
1
Hold

Latest News

Seaport Therapeutics: Borrowed Efficacy, Engineered Safety, And A Post-IPO Discount

Seaport Therapeutics leverages proprietary Glyph technology to enhance bioavailability and safety for CNS drugs, targeting MDD and GAD markets. SPTX maintains a cash runway into 2029, with $427.3 million at June 30, trading at a forward book value discount versus sector peers. Recent clean driving data for GlyphAllo and strong PK data for GlyphAgo de-risk regulatory and commercial pathways ahead of the pivotal BUOY-1 readout.

Seeking Alpha10/29/2026Positive

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Data last updated: 11/7/2026