SMMT

Summit Therapeutics PLC
NASDAQHEALTHCAREBIOTECHNOLOGY

Key Statistics

Market Cap
$12.26B
P/E Ratio
—
EPS
$-1.11
Beta
-1.52
52W High
$29.23
52W Low
$12.07
50-Day MA
$15.66
200-Day MA
$16.31
Dividend Yield
—
Profit Margin
0.00%
Forward P/E
3.72
PEG Ratio
0.00

About Summit Therapeutics PLC

Summit Therapeutics Inc., a biopharmaceutical company, discovers, develops, and markets drugs to treat infectious diseases in the United States, Latin America, and Europe. The company is headquartered in Cambridge, Massachusetts.

Official WebsiteUSAFY End: December

Fundamentals

Revenue (TTM)0
Gross Profit (TTM)705,000
EBITDA$-874.67M
Operating Margin0.00%
Return on Equity-192.50%
Return on Assets-101.60%
Revenue/Share (TTM)$0.00
Book Value$0.79
Price-to-Book20.82
Price-to-Sales (TTM)3891.31
EV/Revenue6425.28
EV/EBITDA-5.32
Quarterly Earnings Growth (YoY)0.00%
Quarterly Revenue Growth (YoY)-100.00%
Shares Outstanding$797.75M
Float$153.88M
% Insiders80.87%
% Institutions17.59%

Historical Volatility

HV 10-Day
68.45%
HV 20-Day
61.13%
HV 30-Day
58.13%
HV 60-Day
70.92%
HV Rank
27.4%

Volatility is currently expanding

Analyst Ratings

Consensus ($30.21 target)
1
Strong Buy
10
Buy
6
Hold

Latest News

Daiichi Sankyo and AstraZeneca Enter into Clinical Trial Collaboration with Summit Therapeutics to Evaluate Datroway® in Combination with Ivonescimab Across Multiple Tumor Types

TOKYO--(BUSINESS WIRE)--Daiichi Sankyo (TSE: 4568) and AstraZeneca (LSE/STO/NYSE: AZN) have entered into a clinical trial collaboration agreement with Summit Therapeutics Inc. (Nasdaq: SMMT) to evaluate Datroway® (datopotamab deruxtecan) in combination with ivonescimab across multiple tumor types including lung and breast cancers. The companies intend to begin with a phase 3 trial in first-line triple negative breast cancer (TNBC). Datroway is a specifically engineered TROP2 directed DXd antibo.

Business Wire10/2/2026Neutral
Summit Therapeutics Announces Clinical Trial Collaboration with AstraZeneca and Daiichi Sankyo to Evaluate Ivonescimab in Combination with TROP2-Directed ADC Datroway

MIAMI--(BUSINESS WIRE)--Summit Therapeutics Inc. (Nasdaq: SMMT) today announced a clinical trial collaboration agreement with Daiichi Sankyo (TSE: 4568) and AstraZeneca (LSE/STO/NYSE: AZN) to evaluate ivonescimab, a novel, potential first-in-class investigational PD-1 / VEGF bispecific antibody, in combination with Datroway® (datopotamab deruxtecan), a TROP2-directed antibody drug conjugate (ADC), across multiple solid tumor settings, intending to include breast and lung cancer. The companies i.

Business Wire10/2/2026Neutral
Summit Therapeutics jumps 20% after AstraZeneca's $2 billion bet: what it signals

Summit Therapeutics shares surged more than 20% in pre-market trading on Tuesday after AstraZeneca agreed to invest $2 billion in the company and collaborate on a series of clinical studies involving their cancer treatments. The deal, announced late Monday, sent UK-listed shares of AstraZeneca 1.9% higher to a two-month high.

Invezz9/29/2026Positive
AstraZeneca Makes $2 Billion Strategic Equity Investment in Summit Therapeutics

MIAMI--(BUSINESS WIRE)--Summit Therapeutics Inc. (Nasdaq: SMMT) today announced key developments important to the company's progress towards achieving its goal of making a significant difference in the lives of patients with cancer. Specifically, Summit has established agreements with AstraZeneca (LSE/STO/NYSE: AZN) for a strategic equity investment in Summit and a clinical collaboration focused on ivonescimab and sonesitatug vedotin (sone-ve). Moreover, Summit and AstraZeneca intend to evaluat.

Business Wire9/28/2026Neutral

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Data last updated: 10/17/2026