SLN

Silence Therapeutics PLC
NASDAQHEALTHCAREBIOTECHNOLOGY

Key Statistics

Market Cap
$479.43M
P/E Ratio
EPS
$-1.55
Beta
1.38
52W High
$11.06
52W Low
$4.19
50-Day MA
$7.43
200-Day MA
$6.35
Dividend Yield
Profit Margin
0.00%
Forward P/E
PEG Ratio

About Silence Therapeutics PLC

Silence Therapeutics plc, a biotechnology company, is focused on the discovery and development of new ribonucleic acid (RNA) therapies in hematology, cardiovascular, and other rare and metabolic indications. The company is headquartered in London, the United Kingdom.

Official WebsiteUSAFY End: December

Fundamentals

Revenue (TTM)839,000
Gross Profit (TTM)667,000
EBITDA$-71.08M
Operating Margin-3565.00%
Return on Equity-92.60%
Return on Assets-29.80%
Revenue/Share (TTM)$0.02
Book Value$1.05
Price-to-Book9.98
Price-to-Sales (TTM)571.43
EV/Revenue169.98
EV/EBITDA-5.78
Quarterly Earnings Growth (YoY)0.00%
Quarterly Revenue Growth (YoY)197.20%
Shares Outstanding$47.23M
Float$25.92M
% Insiders24.63%
% Institutions44.57%

Historical Volatility

HV 10-Day
129.79%
HV 20-Day
105.88%
HV 30-Day
98.88%
HV 60-Day
95.42%
HV Rank
96.0%

Volatility is currently expanding

Analyst Ratings

Consensus ($29.17 target)
1
Strong Buy
5
Buy
1
Sell

Latest News

Silence Therapeutics Highlights Follow-Up Data at EHA 2026 Demonstrating Durable Efficacy and Potential Best-in-Class Profile for Divesiran in Polycythemia Vera

LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc (Nasdaq: SLN), a global clinical-stage biotechnology company developing novel siRNA (short interfering RNA) therapies, today presented follow-up and quality-of-life data from the Phase 1 SANRECO study evaluating divesiran, a first-in-class siRNA therapy targeting TMPRSS6, in 21 phlebotomy-dependent patients with polycythemia vera (PV) at the European Hematology Association (EHA) 2026 Annual Congress. Divesiran data presented at EHA show improvem.

Business Wire6/11/2026Neutral
Silence Therapeutics to Participate in Jefferies Global Healthcare Conference

LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc (Nasdaq: SLN), a global clinical-stage biotechnology company developing novel siRNA (short interfering RNA) therapies, today announced that management will participate in an analyst-led fireside chat at the Jefferies Global Healthcare Conference on Wednesday, June 3, 2026 at 4:55 p.m. ET. A live webcast can be accessed in the Investors section of the Silence website at www.silence-therapeutics.com. An archived replay of the webcast will be avail.

Business Wire5/27/2026Neutral
Silence Therapeutics to Participate in H.C. Wainwright BioConnect Investor Conference

LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc (Nasdaq: SLN), a global clinical-stage company developing novel siRNA (short interfering RNA) therapies, today announced that Curtis Rambaran, MD, Chief Medical Officer of Silence Therapeutics, will participate in a fireside chat at the H.C. Wainwright BioConnect Investor Conference on Tuesday, May 19, 2026 at 2:00 p.m. ET. The live webcast can be accessed in the Investors section of the Silence website at www.silence-therapeutics.com. An archiv.

Business Wire5/12/2026Neutral

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Data last updated: 7/9/2026