SLN

Silence Therapeutics PLC
NASDAQHEALTHCAREBIOTECHNOLOGY

Key Statistics

Market Cap
$1.23B
P/E Ratio
—
EPS
$-1.29
Beta
1.34
52W High
$19.86
52W Low
$4.19
50-Day MA
$13.99
200-Day MA
$9.34
Dividend Yield
—
Profit Margin
0.00%
Forward P/E
—
PEG Ratio
—

About Silence Therapeutics PLC

Silence Therapeutics plc, a biotechnology company, is focused on the discovery and development of new ribonucleic acid (RNA) therapies in hematology, cardiovascular, and other rare and metabolic indications. The company is headquartered in London, the United Kingdom.

Official WebsiteUSAFY End: December

Fundamentals

Revenue (TTM)615,000
Gross Profit (TTM)528,000
EBITDA$-63.94M
Operating Margin-10476.00%
Return on Equity-90.40%
Return on Assets-29.60%
Revenue/Share (TTM)$0.01
Book Value$0.81
Price-to-Book31.91
Price-to-Sales (TTM)1995.55
EV/Revenue1861.38
EV/EBITDA-5.78
Quarterly Earnings Growth (YoY)0.00%
Quarterly Revenue Growth (YoY)197.20%
Shares Outstanding$62.20M
Float$37.85M
% Insiders7.71%
% Institutions49.97%

Historical Volatility

HV 10-Day
67.37%
HV 20-Day
53.37%
HV 30-Day
48.48%
HV 60-Day
80.09%
HV Rank
5.6%

Volatility is currently expanding

Analyst Ratings

Consensus ($19.75 target)
1
Strong Buy
5
Buy
1
Sell

Latest News

BRODSKY & SMITH SHAREHOLDER UPDATE: Notifying Investors of the Following Investigations: Silence Therapeutics plc (Nasdaq – SLN), Option Care Health, Inc. (Nasdaq – OPCH), RXO Inc. (NYSE – RXO), Sangoma Technologies Corporation (Nasdaq – SANG)

BALA CYNWYD, Pa., Oct. 20, 2026 (GLOBE NEWSWIRE) -- Brodsky & Smith reminds investors of the following investigations. If you own shares and wish to discuss the investigation, contact Jason Brodsky (jbrodsky@brodskysmith.com) or Marc Ackerman (mackerman@brodskysmith.com) at 855-576-4847. There is no cost or financial obligation to you.

GlobeNewsWire10/20/2026Neutral
Silence Therapeutics jumps 59% on Merck takeover

Silence Therapeutics PLC (NASDAQ:SLN, FRA:XRP1, OTC:SLNCF), the clinical-stage biotechnology company, surged 59% to $6.11 after agreeing to a $1.3 billion takeover by Merck KGaA, the German pharmaceutical and technology group. Merck will pay $20 in cash for each American depositary share (ADS), representing a 130% premium to Silence's closing price on October 16 and an 82% premium to its 30-day volume-weighted average price.

Proactive Investors10/19/2026Positive
Silence Therapeutics Enters into Agreement to be Acquired by Merck KGaA, Darmstadt, Germany

LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc (Nasdaq: SLN) (“Silence”), a biotechnology company developing precision engineered medicines using its proprietary siRNA technology, today announced that it has entered into a definitive agreement with Merck KGaA, Darmstadt, Germany, pursuant to which Merck KGaA, Darmstadt, Germany has agreed to acquire Silence in an all-cash transaction with an enterprise value of $1.1 billion and an equity value of approximately $1.3 billion, subject to the sa.

Business Wire10/19/2026Neutral
Merck KGaA, Darmstadt, Germany to Acquire Silence Therapeutics, Strengthening Rare Disease Pipeline with Innovative siRNA Asset

DARMSTADT, Germany--(BUSINESS WIRE)--Merck KGaA, Darmstadt, Germany, a leading science and technology company, today announced its entry into a definitive agreement to acquire Silence Therapeutics plc (Nasdaq: SLN), a global clinical-stage biotechnology company headquartered in London, UK, focused on pioneering the design and development of siRNA (short interfering RNA) therapies in areas of high unmet need. The purchase price of $20 per ADS in cash, with each ADS representing three ordinary sh.

Business Wire10/19/2026Neutral

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Data last updated: 11/7/2026