PTGX

Protagonist Therapeutics Inc
NASDAQHEALTHCAREBIOTECHNOLOGY

Key Statistics

Market Cap
$10.26B
P/E Ratio
154.00
EPS
$1.03
Beta
1.79
52W High
$158.95
52W Low
$54.50
50-Day MA
$128.88
200-Day MA
$100.79
Dividend Yield
Profit Margin
29.40%
Forward P/E
38.76
PEG Ratio
0.00

About Protagonist Therapeutics Inc

Protagonist Therapeutics, Inc., a clinical-stage biopharmaceutical company, discovers and develops peptide-based therapeutic drugs to address unmet medical needs. The company is headquartered in Newark, California.

Official WebsiteUSAFY End: December

Fundamentals

Revenue (TTM)$281.99M
Gross Profit (TTM)$281.99M
EBITDA$59.88M
Operating Margin74.40%
Return on Equity11.00%
Return on Assets4.55%
Revenue/Share (TTM)$4.36
Book Value$13.01
Price-to-Book11.93
Price-to-Sales (TTM)36.40
EV/Revenue32.86
EV/EBITDA154.76
Quarterly Earnings Growth (YoY)351.30%
Quarterly Revenue Growth (YoY)3749.00%
Shares Outstanding$64.71M
Float$52.89M
% Insiders0.71%
% Institutions119.81%

Historical Volatility

HV 10-Day
33.68%
HV 20-Day
38.55%
HV 30-Day
48.52%
HV 60-Day
47.13%
HV Rank
71.0%

Volatility is currently contracting

Analyst Ratings

Consensus ($170.38 target)
3
Strong Buy
9
Buy
1
Hold

Latest News

Protagonist Therapeutics Reports Granting of Inducement Awards

NEWARK, CA / ACCESS Newswire / August 18, 2026 / Protagonist Therapeutics, Inc. (Nasdaq:PTGX) today reported that on August 17, 2026, it granted inducement awards to two recently hired employees in accordance with the terms of their employment offer letters. The awards were granted under the Protagonist Therapeutics Amended and Restated Inducement Plan, which was adopted May 29, 2018, and amended February 18, 2020 and February 15, 2022.

Accesswire8/18/2026Neutral
Protagonist Therapeutics: "Strong Buy" ICOTYDE FDA Approval And PN-881 Advancement

Protagonist Therapeutics (PTGX) maintains a "Strong Buy" rating, driven by FDA approval of ICOTYDE for moderate-to-severe plaque psoriasis and strong partnership economics. Company is advancing rusfertide for polycythemia vera, with FDA Priority Review decision expected August 2026 and substantial milestone and royalty potential from Takeda. Development pipeline includes oral IL-17 antagonist PN-881 for psoriasis and other inflammatory disorders, with phase 2b study initiation planned for Q1 2027.

Seeking Alpha8/12/2026Positive
Protagonist Reports Second Quarter 2026 Financial Results and Provides Corporate Update

ICOTYDE™ First Full Quarter of Commercial Sales with Strong Early Adoption Rusfertide NDA under Priority Review for Polycythemia Vera; PDUFA Date in August 2026 Comprehensive Phase 2b Program with PN-881, an Oral IL-17 Antagonist for Psoriasis, Planned to Initiate Early Q1 2027 Phase 1 Study Initiated with PN-477sc, a Triple GLP1/GIP/GCG Agonist Peptide for Obesity Cash, Cash Equivalents and Marketable Securities of $849.5 Million as of June 30, 2026 NEWARK, CA / ACCESS Newswire / August 5, 2026 / Protagonist Therapeutics (Nasdaq:PTGX) ("Protagonist" or "the Company") today reported financial results for the second quarter ended June 30, 2026 and provided a corporate update. "The second quarter of 2026 marked a defining growth phase for Protagonist with a successful commercial launch of ICOTYDE through our strategic partner and accelerating momentum across our internal R&D pipeline.

Accesswire8/5/2026Neutral
Protagonist Therapeutics Reports Granting of Inducement Awards

NEWARK, CA / ACCESS Newswire / August 4, 2026 / Protagonist Therapeutics, Inc. (Nasdaq:PTGX) today reported that on July 31, 2026, it granted inducement awards to two recently hired employees in accordance with the terms of their employment offer letters. The awards were granted under the Protagonist Therapeutics Amended and Restated Inducement Plan, which was adopted May 29, 2018, and amended February 18, 2020 and February 15, 2022.

Accesswire8/4/2026Neutral
Protagonist Therapeutics Reports Granting of Inducement Awards

NEWARK, CA / ACCESS Newswire / July 16, 2026 / Protagonist Therapeutics, Inc. (Nasdaq:PTGX) today reported that on July 15, 2026, it granted inducement awards to three recently hired employees in accordance with the terms of their employment offer letters. The awards were granted under the Protagonist Therapeutics Amended and Restated Inducement Plan, which was adopted May 29, 2018, and amended February 18, 2020 and February 15, 2022.

Accesswire7/16/2026Neutral
New Strong Buy Stocks for July 13th

FOX, LION, EDRY, PTGX and SPH have been added to the Zacks Rank #1 (Strong Buy) List on July 13th, 2026.

Zacks Investment Research7/13/2026Positive
New Strong Buy Stocks for July 9th

PTGX, DHX, COOK, XYZ and ARLP have been added to the Zacks Rank #1 (Strong Buy) List on July 9, 2026.

Zacks Investment Research7/9/2026Positive

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Data last updated: 8/18/2026