
Puma Biotechnology, Inc. (PBYI) Q3 2026 Earnings Call Prepared Remarks Transcript
Puma Biotechnology, Inc., a biopharmaceutical company, focuses on the development and commercialization of products to improve cancer care in the United States and internationally. The company is headquartered in Los Angeles, California.
| Revenue (TTM) | $231.87M |
| Gross Profit (TTM) | $170.61M |
| EBITDA | $35.50M |
| Operating Margin | 9.62% |
| Return on Equity | 22.00% |
| Return on Assets | 9.81% |
| Revenue/Share (TTM) | $4.55 |
| Book Value | $2.59 |
| Price-to-Book | 3.64 |
| Price-to-Sales (TTM) | 1.84 |
| EV/Revenue | 1.798 |
| EV/EBITDA | 9.21 |
| Quarterly Earnings Growth (YoY) | -35.30% |
| Quarterly Revenue Growth (YoY) | 1.10% |
| Shares Outstanding | $51.62M |
| Float | $39.76M |
| % Insiders | 15.37% |
| % Institutions | 75.82% |
Volatility is currently expanding

Puma Biotechnology, Inc. (PBYI) Q3 2026 Earnings Call Prepared Remarks Transcript

Puma Biotechnology NASDAQ: PBYI reported third-quarter 2026 revenue of $55.1 million and raised its full-year net income forecast, even as it lowered its outlook for royalties and narrowed its sales guidance for breast cancer drug NERLYNX.

PBYI raised its 2026 Nerlynx sales outlook after 3.5% first-half 2026 growth, with Q3 revenues expected to reach $54-$56 million.

AZN, RHHBY, PBYI and OLMA offer exposure to breast cancer drug sales growth, expanded treatment approvals and clinical milestones that could shape prospects.

LOS ANGELES--(BUSINESS WIRE)--Puma Biotechnology announced the grant of an inducement award to one new hire in Sept. 2026, as required under Nasdaq Listing Rule 5635(c)(4).

Puma Biotechnology starts the ALISCA-Lung2 phase II study evaluating alisertib in combination with paclitaxel in patients with advanced small cell lung cancer.

NERLYNX gives PBYI an established revenue stream that can support alisertib's development into a potential second oncology franchise. Currently, PBYI already has positive cash flows and a healthy balance sheet, which I believe should give them flexibility as their R&D progresses. Alisertib's biomarker strategy could identify responsive patients, but bear in mind that it's still a speculative asset in Phase 2 trials.

Here at Zacks, our focus is on the proven Zacks Rank system, which emphasizes earnings estimates and estimate revisions to find great stocks. Nevertheless, we are always paying attention to the latest value, growth, and momentum trends to underscore strong picks.

Puma Biotechnology tops Q2 earnings and revenue estimates, raises its 2026 guidance, and outlines upcoming alisertib study milestones as Nerlynx sales climb.

Puma Biotechnology, Inc. (PBYI) Q2 2026 Earnings Call Transcript
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