ORKA

Oruka Therapeutics, Inc.
NASDAQHEALTHCAREBIOTECHNOLOGY

Key Statistics

Market Cap
$6.81B
P/E Ratio
—
EPS
$-2.18
Beta
-0.17
52W High
$115.52
52W Low
$25.23
50-Day MA
$88.22
200-Day MA
$70.86
Dividend Yield
—
Profit Margin
0.00%
Forward P/E
—
PEG Ratio
—

About Oruka Therapeutics, Inc.

Oruka Therapeutics, Inc. is a biotechnology company.

Official WebsiteUSAFY End: December

Fundamentals

Revenue (TTM)0
Gross Profit (TTM)0
EBITDA$-154.94M
Operating Margin0.00%
Return on Equity-18.20%
Return on Assets-13.00%
Revenue/Share (TTM)$0.00
Book Value$18.20
Price-to-Book5.72
Price-to-Sales (TTM)—
EV/Revenue-
EV/EBITDA—
Quarterly Earnings Growth (YoY)0.00%
Quarterly Revenue Growth (YoY)0.00%
Shares Outstanding$66.21M
Float$56.89M
% Insiders1.26%
% Institutions116.50%

Historical Volatility

HV 10-Day
77.90%
HV 20-Day
67.51%
HV 30-Day
61.66%
HV 60-Day
55.02%
HV Rank
40.1%

Volatility is currently expanding

Analyst Ratings

Consensus ($156.17 target)
2
Strong Buy
11
Buy

Latest News

Oruka Therapeutics to Participate in Multiple Upcoming Conferences

MENLO PARK, Calif., Nov. 03, 2026 (GLOBE NEWSWIRE) -- Oruka Therapeutics, Inc. (“Oruka”) (Nasdaq: ORKA), a clinical-stage biotechnology company developing novel biologics designed to set a new standard for the treatment of chronic skin diseases including plaque psoriasis and hidradenitis suppurativa, today announced its participation and presentation at multiple upcoming conferences: Guggenheim 3 rd Annual Healthcare Innovation Conference Date: November 10, 2026 Presentation Time: 11:00 AM EST Stifel 2026 Healthcare Conference Date: November 11, 2026 Presentation Time: 4:00 PM EST UBS Global Biopharma Conference Date: November 17, 2026 Presentation Time: 4:00 PM GMT Jefferies Global Healthcare Conference Date: November 18, 2026 Presentation Time: 4:30 PM GMT Webcasts and replays of Oruka's presentations will be available on the Oruka investor events website at https://ir.orukatx.com/news-events/events-presentations.

GlobeNewsWire11/3/2026Neutral
Oruka's ORKA-001 Delivers 61% Complete Skin Clearance in Phase IIb Psoriasis Study

Oruka Therapeutics NASDAQ: ORKA reported interim week 16 results from EVERLAST-B, a Phase IIb dose-ranging study of ORKA-001 in adults with moderate-to-severe plaque psoriasis. The company said its 600-milligram regimen achieved complete skin clearance, measured by PASI 100, in 61% of participants at week 16, while 86% achieved PASI 90.

MarketBeat10/27/2026Neutral
Oruka Therapeutics to Host Conference Call to Report Week 16 Data for ORKA-001 from the Ongoing EVERLAST-B Trial on October 26, 2026

MENLO PARK, Calif., Oct. 25, 2026 (GLOBE NEWSWIRE) -- Oruka Therapeutics, Inc. (“Oruka”) (Nasdaq: ORKA), a clinical-stage biotechnology company developing novel biologics designed to set a new standard for the treatment of chronic skin diseases including plaque psoriasis (PsO) and hidradenitis suppurativa (HS), today announced it will report Week 16 data for ORKA-001 from the ongoing EVERLAST-B Phase 2b trial in moderate-to-severe plaque psoriasis on Monday, October 26, 2026. Following the announcement, the company will host a conference call and webcast at 8:00 a.m. ET to discuss the results.

GlobeNewsWire10/25/2026Neutral
Oruka Therapeutics Announces Positive Week 28 Data for ORKA-001 from the Ongoing EVERLAST-A Trial Showing Deepening of Responses Without Additional Dosing

PASI 100 increased to 71.4% and PASI 90 increased to 87.3%, despite no dosing after Week 4 Placebo crossover patients reached PASI 100 and PASI 90 rates similar to those initially dosed with ORKA-001 ORKA-001 maintained a favorable safety and tolerability profile through Week 28 52-week EVERLAST-A data for all patients expected in December 2026 16-week EVERLAST-B data expected in 4Q 2026 MENLO PARK, Calif., Sept. 23, 2026 (GLOBE NEWSWIRE) -- Oruka Therapeutics, Inc. (“Oruka”) (Nasdaq: ORKA), a clinical-stage biotechnology company developing novel biologics designed to set a new standard for the treatment of chronic skin diseases including plaque psoriasis (PsO) and hidradenitis suppurativa (HS), today announced positive Week 28 results from its EVERLAST-A Phase 2a trial of ORKA-001, a novel half-life extended IL-23p19 monoclonal antibody, in moderate-to-severe plaque psoriasis.

GlobeNewsWire9/23/2026Neutral
Oruka Therapeutics to Attend the 2026 Morgan Stanley Global Healthcare Conference

MENLO PARK, Calif., Sept. 09, 2026 (GLOBE NEWSWIRE) -- Oruka Therapeutics, Inc. (“Oruka”) (Nasdaq: ORKA), a clinical-stage biotechnology company developing novel biologics designed to set a new standard for the treatment of chronic skin diseases including plaque psoriasis and hidradenitis suppurativa, today announced its attendance at the 2026 Morgan Stanley Global Healthcare Conference, taking place in New York, NY from September 14-16, 2026. About Oruka Therapeutics Oruka Therapeutics is developing novel biologics designed to set a new standard for the treatment of chronic skin diseases. Oruka's mission is to offer patients suffering from inflammatory diseases like plaque psoriasis and hidradenitis suppurativa the greatest possible freedom from their condition by achieving high rates of disease clearance with dosing as infrequently as once or twice a year. For more information, visit www.orukatx.com and follow Oruka on LinkedIn.

GlobeNewsWire9/9/2026Neutral
Oruka Therapeutics Appoints Todd Edwards as Chief Commercial Officer

MENLO PARK, Calif., Aug. 24, 2026 (GLOBE NEWSWIRE) -- Oruka Therapeutics, Inc. ("Oruka") (Nasdaq: ORKA), a clinical-stage biotechnology company developing novel biologics designed to set a new standard for the treatment of chronic skin diseases including plaque psoriasis (PsO) and hidradenitis suppurativa (HS), today announced the appointment of Todd Edwards as Chief Commercial Officer, effective August 24, 2026.

GlobeNewsWire8/24/2026Neutral

Turn research into an automated options-selling system

Tiblio connects your broker and runs your put-and-call-writing strategy for you — on ORKA and any ticker you trade — then tracks every position and per-strategy win rate.

See how it works

More HEALTHCARE Stocks

Data last updated: 11/7/2026