Oruka Therapeutics, Inc. (ORKA)

US — Healthcare Sector
Peers: PHAT  BBOT  RAPP  KOD  XNCR  NRIX  ANAB  URGN  OCS  MNMD 

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News

Oruka Therapeutics: A Potential Future Psoriasis Play
ORKA
Published: February 25, 2026 by: Seeking Alpha
Sentiment: Positive

Oruka Therapeutics, Inc. has surged after ORKA-001 showed a half-life four times Skyrizi in Phase 1, targeting the $30B psoriasis market. ORKA-001 and ORKA-002 aim for best-in-class efficacy with dramatically less frequent dosing, potentially shifting the treatment paradigm for chronic skin diseases. Phase 2a EVERLAST-A results for ORKA-001 are expected in 2H26; meaningful revenue is not anticipated until 2031, highlighting ORKA stock's long-term, high-risk profile.

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Oruka Therapeutics to Present at Multiple November Investor Conferences
ORKA
Published: October 29, 2025 by: GlobeNewsWire
Sentiment: Neutral

MENLO PARK, Calif., Oct. 29, 2025 (GLOBE NEWSWIRE) -- Oruka Therapeutics, Inc. (“Oruka”) (Nasdaq: ORKA), a clinical stage biotechnology company developing novel biologics designed to set a new standard for the treatment of chronic skin diseases including plaque psoriasis, today announced presentations at the following upcoming investor conferences:

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image for news Oruka Therapeutics to Present at Multiple November Investor Conferences
Oruka Therapeutics Announces $180 Million Private Placement
ORKA
Published: September 17, 2025 by: GlobeNewsWire
Sentiment: Neutral

MENLO PARK, Calif., Sept. 17, 2025 (GLOBE NEWSWIRE) -- Oruka Therapeutics, Inc. (“Oruka” or the “Company”) (Nasdaq: ORKA), a biotechnology company developing novel biologics designed to set a new standard for the treatment of chronic skin diseases, including plaque psoriasis, today announced that it has entered into a securities purchase agreement for a private investment in public equity (“PIPE”) financing that is expected to result in gross proceeds of approximately $180 million to the Company, before placement agent fees and offering expenses. The PIPE financing was led by Viking Global Investors, and included participation from both new and existing investors, …

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Oruka Therapeutics Announces Positive Interim Phase 1 Results for ORKA-001
ORKA
Published: September 17, 2025 by: GlobeNewsWire
Sentiment: Neutral

Half-life of approximately 100 days increases likelihood of once-per-year dosing Pharmacokinetic profile supports the ability to achieve exposures that could lead to higher efficacy and extended off-treatment remissions Well tolerated with a favorable safety profile consistent with the IL-23p19 class EVERLAST-A Phase 2a trial enrollment ongoing with data expected 2H 2026 MENLO PARK, Calif., Sept. 17, 2025 (GLOBE NEWSWIRE) -- Oruka Therapeutics, Inc. (“Oruka”) (Nasdaq: ORKA), a biotechnology company developing novel biologics designed to set a new standard for the treatment of chronic skin diseases including plaque psoriasis (PsO), today announced interim data from its Phase 1 trial of ORKA-001, …

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Oruka Therapeutics Announces IND Clearance for EVERLAST-A Phase 2a Trial of ORKA-001 in Psoriasis with Phase 1 Data to be Presented at EADV in September
ORKA
Published: July 21, 2025 by: GlobeNewsWire
Sentiment: Neutral

IND cleared for the EVERLAST-A Phase 2a trial of ORKA-001 in moderate-to-severe psoriasis, with initial data expected 2H 2026

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image for news Oruka Therapeutics Announces IND Clearance for EVERLAST-A Phase 2a Trial of ORKA-001 in Psoriasis with Phase 1 Data to be Presented at EADV in September
Oruka Therapeutics to Present at Multiple March Investor Conferences
ORKA
Published: February 19, 2025 by: GlobeNewsWire
Sentiment: Neutral

MENLO PARK, Calif., Feb. 19, 2025 (GLOBE NEWSWIRE) -- Oruka Therapeutics, Inc. (“Oruka”) (Nasdaq: ORKA), a clinical stage biotechnology company developing novel biologics designed to set a new standard for the treatment of chronic skin diseases including plaque psoriasis, today announced presentations at the following upcoming investor conferences:

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image for news Oruka Therapeutics to Present at Multiple March Investor Conferences

About Oruka Therapeutics, Inc. (ORKA)

  • IPO Date 1997-08-08
  • Website http://www.orukatx.com
  • Industry Biotechnology
  • CEO Lawrence Otto Klein
  • Employees 28

Oruka Therapeutics, Inc. is a biotechnology company, which focuses on developing novel monoclonal antibody therapeutics for PsO and other I&I indications. Its pipeline includes ORKA-001 and ORKA-002. The company is headquartered in Menlo Park, CA.