OBIO

Orchestra BioMed Holdings Inc.
NASDAQHEALTHCAREBIOTECHNOLOGY

Key Statistics

Market Cap
$341.40M
P/E Ratio
—
EPS
$-0.86
Beta
0.55
52W High
$6.50
52W Low
$3.46
50-Day MA
$5.73
200-Day MA
$4.57
Dividend Yield
—
Profit Margin
-184.60%
Forward P/E
—
PEG Ratio
—

About Orchestra BioMed Holdings Inc.

Orchestra BioMed Holdings, Inc. is a therapeutic device company that develops therapeutic treatments and products for cardiovascular diseases. The company is headquartered in New Hope, Pennsylvania.

Official WebsiteUSAFY End: December

Fundamentals

Revenue (TTM)$31.98M
Gross Profit (TTM)$31.82M
EBITDA$-57.64M
Operating Margin-25405.00%
Return on Equity-397.30%
Return on Assets-45.70%
Revenue/Share (TTM)$0.54
Book Value$0.32
Price-to-Book17.45
Price-to-Sales (TTM)10.68
EV/Revenue8.24
EV/EBITDA-1.81
Quarterly Earnings Growth (YoY)0.00%
Quarterly Revenue Growth (YoY)-89.50%
Shares Outstanding$60.10M
Float$32.98M
% Insiders24.39%
% Institutions47.80%

Historical Volatility

HV 10-Day
67.54%
HV 20-Day
59.51%
HV 30-Day
56.54%
HV 60-Day
67.01%
HV Rank
36.1%

Volatility is currently expanding

Analyst Ratings

Consensus ($12.43 target)
1
Strong Buy
6
Buy

Latest News

Orchestra BioMed Announces Pricing of Public Offering

NEW HOPE, Pa., Nov. 05, 2026 (GLOBE NEWSWIRE) -- Orchestra BioMed Holdings, Inc. (Nasdaq: OBIO) (“Orchestra BioMed” or the “Company”), a biomedical innovation company accelerating high-impact technologies to patients through strategic collaborations with market-leading global medical device companies, announced today the pricing of an underwritten public offering of 15,000,000 shares of its common stock at a price to the public of $5.00 per share (the “Offering”).

GlobeNewsWire11/6/2026Neutral
Orchestra BioMed Announces Virtue SAB Presentation at TCT 2026

Presentation will highlight Virtue SAB's fundamentally different approach of infusing a large liquid volume of proprietary extended-release SirolimusEFR™ directly into and throughout the vessel wall. Virtue SAB's mechanism is designed to achieve sustained, transmural sirolimus tissue levels substantially exceeding those achieved by drug-eluting stents and drug-coated balloons.

GlobeNewsWire10/29/2026Neutral
Orchestra BioMed Exceeds Full Enrollment Target in the BACKBEAT Global Pivotal Trial of AVIM Therapy

330 patients randomized as of September 30, 2026, surpassing full trial enrollment target Company reiterates prior guidance: primary endpoint data to be submitted for late-breaking presentation consideration at a major cardiovascular conference in Q2 2027 Data expected to support future marketing application submissions by Medtronic to the FDA and other global regulatory agencies NEW HOPE, Pa., Oct. 01, 2026 (GLOBE NEWSWIRE) -- Orchestra BioMed Holdings, Inc. (Nasdaq: OBIO) (“Orchestra BioMed” or the “Company”), a biomedical company accelerating high-impact technologies to patients through strategic partnerships with market-leading medical device companies, today announced that it has surpassed full enrollment in the BACKBEAT Global Pivotal Trial (“BACKBEAT Trial”), exceeding its previously announced target of 316 randomized patients.

GlobeNewsWire10/1/2026Neutral
Orchestra BioMed Announces AVIM Therapy to Be Featured in Two Sessions at HRX Live 2026

NEW HOPE, Pa., Sept. 16, 2026 (GLOBE NEWSWIRE) -- Orchestra BioMed Holdings, Inc. (Nasdaq: OBIO) ("Orchestra BioMed" or the "Company"), a biomedical company accelerating high-impact technologies to patients through strategic partnerships with market-leading global medical device companies, today announced that its investigational Atrioventricular Interval Modulation Therapy ("AVIM Therapy") will be featured in two sessions at HRX Live 2026 -- the Heart Rhythm Society's annual innovation-focused meeting taking place September 18-20, 2026, in Atlanta, Georgia.

GlobeNewsWire9/16/2026Neutral
Orchestra BioMed Receives $6.1 Million Milestone Payment from Acquisition of Vivasure by Haemonetics

Payment follows approximately $5 million received in January 2026, bringing total cash proceeds received to approximately $11 million Company remains eligible for up to approximately $10 million in additional proceeds through future revenue earnouts Monetization of a strategic holding provides additional capital to advance Orchestra BioMed's pivotal programs and reflects its approach to creating value through partnerships NEW HOPE, Pa., Sept. 15, 2026 (GLOBE NEWSWIRE) -- Orchestra BioMed Holdings, Inc. (Nasdaq: OBIO, “Orchestra BioMed” or the “Company”), a biomedical company accelerating high-impact technologies to patients through strategic partnerships with market-leading global medical device companies, today announced the receipt of $6.1 million on September 14, 2026, as the first milestone payment in connection with the previously announced acquisition of Vivasure Medical Limited (“Vivasure”) by Haemonetics Corporation (NYSE: HAE, “Haemonetics”).

GlobeNewsWire9/15/2026Neutral
Orchestra BioMed Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

NEW HOPE, Pa., Sept. 02, 2026 (GLOBE NEWSWIRE) -- Orchestra BioMed Holdings, Inc. (Nasdaq: OBIO) (“Orchestra BioMed” or the “Company”), a biomedical company accelerating high-impact technologies to patients through strategic partnerships with market-leading global medical device companies, reported today that, on September 1, 2026, the Compensation Committee of the Orchestra BioMed Board of Directors granted stock options to purchase an aggregate of 133,000 shares of the Company's common stock to seven newly hired employees.

GlobeNewsWire9/2/2026Neutral
Orchestra BioMed to Participate in the Wells Fargo 21st Annual Healthcare Conference

NEW HOPE, Pa., Aug. 20, 2026 (GLOBE NEWSWIRE) -- Orchestra BioMed Holdings, Inc. (Nasdaq: OBIO, “Orchestra BioMed” or the “Company”), a biomedical company accelerating high-impact technologies to patients through risk-reward sharing partnerships, today announced that Chairman and CEO David Hochman will present at the Wells Fargo 21st Annual Healthcare Conference on Thursday, Sept. 10, 2026 at 1:30pm ET and will also host one-on-one meetings with investors that day and on Wednesday, Sept. 9.

GlobeNewsWire8/20/2026Neutral

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Data last updated: 11/7/2026