KRYS

Krystal Biotech Inc
NASDAQHEALTHCAREBIOTECHNOLOGY

Key Statistics

Market Cap
$8.90B
P/E Ratio
40.79
EPS
$7.36
Beta
0.65
52W High
$382.54
52W Low
$197.13
50-Day MA
$333.62
200-Day MA
$308.95
Dividend Yield
—
Profit Margin
47.90%
Forward P/E
44.84
PEG Ratio
—

About Krystal Biotech Inc

Krystal Biotech, Inc., a clinical-stage biotechnology company, is dedicated to the field of redosable gene therapy to treat serious rare diseases in the United States. The company is headquartered in Pittsburgh, Pennsylvania.

Official WebsiteUSAFY End: December

Fundamentals

Revenue (TTM)$470.02M
Gross Profit (TTM)$443.12M
EBITDA$229.03M
Operating Margin55.90%
Return on Equity17.50%
Return on Assets10.10%
Revenue/Share (TTM)$16.00
Book Value$48.45
Price-to-Book6.42
Price-to-Sales (TTM)18.93
EV/Revenue17.68
EV/EBITDA35.46
Quarterly Earnings Growth (YoY)-22.90%
Quarterly Revenue Growth (YoY)30.20%
Shares Outstanding$29.63M
Float$23.65M
% Insiders10.65%
% Institutions101.15%

Historical Volatility

HV 10-Day
68.99%
HV 20-Day
53.55%
HV 30-Day
46.72%
HV 60-Day
39.80%
HV Rank
88.1%

Volatility is currently expanding

Analyst Ratings

Consensus ($388.22 target)
1
Strong Buy
10
Buy
1
Hold

Latest News

Krystal Biotech Q3 Earnings Call Highlights

Krystal Biotech NASDAQ: KRYS reported third-quarter 2026 revenue growth driven by continued adoption of its VYJUVEK treatment in the United States and international markets, while also outlining updated timelines for several clinical programs and authorizing a share repurchase program of up to $400 million.

MarketBeat11/2/2026Neutral
Krystal Biotech Announces Third Quarter 2026 Financial and Operating Results

$127.3 million in 3Q VYJUVEK global revenue and $1.1 billion since launch VYJUVEK pricing negotiations in Germany and Italy completed KB113 clinical data demonstrate regression in more than 80% of assessed basal cell carcinoma lesions in patients with Gorlin syndrome Strong balance sheet, ending the quarter with $1.2 billion in cash and investments Board authorizes share repurchase program of up to $400 million PITTSBURGH, Nov. 02, 2026 (GLOBE NEWSWIRE) -- Krystal Biotech, Inc. (the “Company” or “Krystal”) (NASDAQ: KRYS) today reported financial results for the third quarter ended September 30, 2026 and provided a business update. “Continued growth in VYJUVEK revenue is supporting profitability and funding the advancement of our pipeline,” said Krish S.

GlobeNewsWire11/2/2026Neutral
Krystal Biotech to Report Third Quarter 2026 Financial Results on November 2, 2026

PITTSBURGH, Oct. 22, 2026 (GLOBE NEWSWIRE) -- Krystal Biotech, Inc. (the “Company”) (NASDAQ: KRYS) announced today that it will report its third quarter 2026 financial results on Monday, November 2, 2026, prior to the open of U.S. markets. The Company's management will also host a conference call and webcast at 8:30 am ET on Monday, November 2, 2026, to discuss the financial results and provide a business update.

GlobeNewsWire10/22/2026Neutral
Krystal Biotech Announces Positive Clinical Data for New Dermatology Program KB113 Demonstrating Broad Basal Cell Carcinoma Regression in Patients with Gorlin Syndrome

Over 80% of assessed basal cell carcinoma lesions regressed across three Gorlin syndrome patients treated with KB113 Substantial regression was observed in lesions not directly injected with KB113, consistent with abscopal effect KB113 injections were well tolerated by Gorlin syndrome patients; all reported adverse events were mild to moderate in severity and transient in nature Data will be presented by study investigator Dr. Shireen Guide at the 14th PeDRA Annual Conference, October 15-17, 2026 PITTSBURGH, Oct. 15, 2026 (GLOBE NEWSWIRE) -- Krystal Biotech, Inc. (the “Company”) (NASDAQ: KRYS) announced today a positive clinical update supporting initial proof of concept for KB113, an intratumoral immunotherapy designed to drive sustained, localized expression of interleukin-2 (IL-2) and interleukin-12 (IL-12) in the tumor microenvironment and promote systemic immune-mediated tumor clearance, in the treatment of basal cell carcinomas (BCCs) in patients with Gorlin syndrome: Broad antitumor responses were detected in all three Gorlin syndrome patients treated with KB113, with over 80% of assessed BCC lesions reducing in size; Responses were observed in both injected and non-injected lesions, including substantial regression in lesions that were not directly injected with KB113, consistent with an abscopal effect; and Complete clearance of an injected lesion was also confirmed histologically for each of the three patients treated with KB113. Gorlin syndrome is a genetic disease characterized by a greatly increased risk of developing BCCs.

GlobeNewsWire10/15/2026Neutral

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Data last updated: 11/7/2026