IONS

Ionis Pharmaceuticals Inc
NASDAQHEALTHCAREBIOTECHNOLOGY

Key Statistics

Market Cap
$12.36B
P/E Ratio
EPS
$-2.01
Beta
0.40
52W High
$86.74
52W Low
$31.66
50-Day MA
$75.46
200-Day MA
$69.53
Dividend Yield
Profit Margin
-30.90%
Forward P/E
90.91
PEG Ratio
25.70

About Ionis Pharmaceuticals Inc

Ionis Pharmaceuticals, Inc. discovers and develops RNA-targeted therapies in the United States. The company is headquartered in Carlsbad, California.

Official WebsiteUSAFY End: December

Fundamentals

Revenue (TTM)$1.06B
Gross Profit (TTM)$115.73M
EBITDA$-338.65M
Operating Margin-47.70%
Return on Equity-67.60%
Return on Assets-7.03%
Revenue/Share (TTM)$6.55
Book Value$2.98
Price-to-Book25.14
Price-to-Sales (TTM)11.68
EV/Revenue11.79
EV/EBITDA135.77
Quarterly Earnings Growth (YoY)-43.70%
Quarterly Revenue Growth (YoY)87.00%
Shares Outstanding$165.26M
Float$163.98M
% Insiders0.66%
% Institutions106.04%

Historical Volatility

HV 10-Day
25.68%
HV 20-Day
23.91%
HV 30-Day
27.73%
HV 60-Day
31.32%
HV Rank
15.5%

Volatility is currently contracting

Analyst Ratings

Consensus ($98.61 target)
6
Strong Buy
10
Buy
6
Hold
Data last updated: 5/1/2026