GPCR

Structure Therapeutics Inc. American Depositary Shares
NASDAQHEALTHCAREBIOTECHNOLOGY

Key Statistics

Market Cap
$1.45B
P/E Ratio
—
EPS
$-3.03
Beta
-1.20
52W High
$94.90
52W Low
$18.70
50-Day MA
$31.10
200-Day MA
$47.67
Dividend Yield
—
Profit Margin
0.00%
Forward P/E
—
PEG Ratio
—

About Structure Therapeutics Inc. American Depositary Shares

Structure Therapeutics Inc., a clinical stage global biopharmaceutical company, develops and delivers novel oral therapeutics to treat a range of chronic diseases with unmet medical needs. The company is headquartered in South San Francisco, California.

Official WebsiteUSAFY End: December

Fundamentals

Revenue (TTM)0
Gross Profit (TTM)0
EBITDA$-265.79M
Operating Margin0.00%
Return on Equity-20.20%
Return on Assets-14.90%
Revenue/Share (TTM)$0.00
Book Value$19.02
Price-to-Book1.00
Price-to-Sales (TTM)—
EV/Revenue-
EV/EBITDA-13.46
Quarterly Earnings Growth (YoY)0.00%
Quarterly Revenue Growth (YoY)0.00%
Shares Outstanding$71.31M
Float$55.46M
% Insiders3.11%
% Institutions96.84%

Historical Volatility

HV 10-Day
61.59%
HV 20-Day
62.60%
HV 30-Day
58.33%
HV 60-Day
59.77%
HV Rank
—

Volatility is currently expanding

Analyst Ratings

Consensus ($107.29 target)
4
Strong Buy
11
Buy
1
Hold

Latest News

Structure Therapeutics to Participate in the Jefferies Global Healthcare Conference

SAN FRANCISCO, Nov. 04, 2026 (GLOBE NEWSWIRE) -- Structure Therapeutics Inc. (NASDAQ: GPCR), a clinical-stage global biopharmaceutical company developing novel oral small molecule therapeutics for metabolic diseases, with a focus on chronic weight management, today announced that management will participate in the Jefferies Global Healthcare Conference being held November 16-19, 2026 in London, UK. Jefferies Global Healthcare Conference Date: Tuesday, November 17Format: Fireside chat and 1x1 meetingsTime: 12:00 PM GMTLocation: London, UK The live and archived webcasts will be accessible from the company's website at  https://ir.structuretx.com/events-presentations/events  and replays will be available for at least 90 days.

GlobeNewsWire11/4/2026Neutral
Structure Therapeutics Announces Multiple Upcoming Presentations at ObesityWeek® 2026

SAN FRANCISCO, Oct. 19, 2026 (GLOBE NEWSWIRE) -- Structure Therapeutics Inc. (NASDAQ: GPCR), a clinical-stage global biopharmaceutical company developing novel oral small molecule therapeutics for metabolic diseases, with a focus on chronic weight management, today announced multiple upcoming poster presentations at The Obesity Society's Annual Meeting, ObesityWeek®, taking place from November 14–17, 2026 in National Harbor, MD. Title: Aleniglipron in Participants Living with Overweight or Obesity: ACCESS Trial Open-Label Extension Date/Time: November 15, 2026, 2:30 p.m.

GlobeNewsWire10/19/2026Neutral
Structure Therapeutics: The Amylin Data Changes The Math

Structure Therapeutics remains a Strong Buy, with recent data de-risking its lead oral obesity drug, aleniglipron. Aleniglipron's 72-week open-label data showed 16.2% weight loss, low AE discontinuations, and no DILI, though Phase 3 efficacy and safety monitoring remain key. ACCG-2671, an oral amylin agonist, now has human data and offers potential for combination therapy, further differentiating GPCR's pipeline.

Seeking Alpha9/9/2026Positive
Structure Therapeutics Reports Positive Clinical Data Across Oral Small Molecule Amylin and GLP-1 Programs for Chronic Weight Management

ACCG-2671 (oral small molecule amylin receptor agonist) demonstrated a ~6-day half-life, no serious adverse events, and evidence of target engagement including up to 3.3% body weight loss in Phase 1/2a SAD clinical trial First participants dosed with ACCG-2671 in the 12-week MAD portion of the Phase 1/2a clinical trial; topline data expected in 1H 2027 Aleniglipron (oral small molecule selective GLP-1 receptor agonist) demonstrated up to 16.2% mean reduction in body weight at 72 weeks with no observed plateau, and improved tolerability with a 2.5 mg starting dose, including less than 5% study-drug discontinuation rates due to adverse events in the ACCESS OLE clinical trial ACCOMPLISH-1 and ACCOMPLISH-2 registrational Phase 3 clinical trials for aleniglipron enrollment ongoing; topline data expected in 2H 2028 Company to host conference call today at 8:30 a.m. ET SAN FRANCISCO, Sept.

GlobeNewsWire9/8/2026Neutral
Structure Therapeutics to Participate in Upcoming Healthcare Investor Conferences

SAN FRANCISCO, Sept. 03, 2026 (GLOBE NEWSWIRE) -- Structure Therapeutics Inc. (NASDAQ: GPCR), a clinical-stage global biopharmaceutical company developing novel oral small molecule therapeutics for metabolic diseases, with a focus on obesity, today announced that management will participate in three upcoming healthcare conferences in September: 2026 Cantor Global Healthcare Conference Date: Thursday, September 10Format: Fireside chat and 1x1 meetingsTime: 3:55 – 4:25 PM EDTLocation: New York, NY Morgan Stanley 24 th Annual Global Healthcare Conference Date: Wednesday, September 16Format: Fireside chat and 1x1 meetingsTime: 10:45 – 11:20 AM EDTLocation: New York, NY Bernstein's 3rd Annual Healthcare Forum Date: Wednesday, September 23Format: Fireside Chat and 1x1 meetingsTime: 3:00 – 3:40 PM EDTLocation: New York, NY The live and archived webcasts will be accessible from the company's website at https://ir.structuretx.com/events-presentations/events and replays will be available for at least 90 days.

GlobeNewsWire9/3/2026Neutral

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Data last updated: 11/7/2026