CRISPR Therapeutics AG (CRSP)

CH — Healthcare Sector
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Key Metrics & Ratings

  • symbol CRSP
  • Rev/Share 0.4025
  • Book/Share 20.9843
  • PB 2.478
  • Debt/Equity 0.1101
  • CurrentRatio 16.2167
  • ROIC -0.2678

 

  • MktCap 4955610400.0
  • FreeCF/Share -3.3201
  • PFCF -16.3474
  • PE -9.7233
  • Debt/Assets 0.094
  • DivYield 0
  • ROE -0.2644

 

  • Rating C-
  • Score 1
  • Recommendation Strong Sell
  • P/E Score 1
  • DCF Score 1
  • P/B Score 2
  • D/E Score 3

Recent Analyst Ratings

Type Ticker Analyst Firm Previous Rating Current Rating Previous Price Target Current Price Target Date
Initiation CRSP JP Morgan -- Overweight -- $70 Sept. 18, 2025
Upgrade CRSP Evercore ISI In-line Outperform $60 $99 Feb. 14, 2025
Upgrade CRSP TD Cowen Sell Hold -- $35 Feb. 12, 2025
Initiation CRSP H.C. Wainwright -- Buy -- $65 Feb. 3, 2025

News

CRISPR Therapeutics AG (CRSP) Expected to Beat Earnings Estimates: Should You Buy?
CRSP
Published: February 03, 2026 by: Zacks Investment Research
Sentiment: Positive

CRISPR Therapeutics (CRSP) possesses the right combination of the two key ingredients for a likely earnings beat in its upcoming report. Get prepared with the key expectations.

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image for news CRISPR Therapeutics AG (CRSP) Expected to Beat Earnings Estimates: Should You Buy?
CRSP to Report Q4 Earnings: Is a Beat in Store for the Stock?
CRSP
Published: February 03, 2026 by: Zacks Investment Research
Sentiment: Positive

CRISPR Therapeutics heads into Q4 earnings with rising Casgevy sales, collaboration revenues from Vertex, and a history of beating estimates.

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image for news CRSP to Report Q4 Earnings: Is a Beat in Store for the Stock?
CRISPR Therapeutics AG (CRSP) Surpasses Market Returns: Some Facts Worth Knowing
CRSP
Published: February 02, 2026 by: Zacks Investment Research
Sentiment: Positive

In the closing of the recent trading day, CRISPR Therapeutics AG (CRSP) stood at $51.31, denoting a +2.7% move from the preceding trading day.

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image for news CRISPR Therapeutics AG (CRSP) Surpasses Market Returns: Some Facts Worth Knowing
CRISPR Therapeutics AG (CRSP) Is a Trending Stock: Facts to Know Before Betting on It
CRSP
Published: January 26, 2026 by: Zacks Investment Research
Sentiment: Positive

CRISPR Therapeutics (CRSP) has received quite a bit of attention from Zacks.com users lately. Therefore, it is wise to be aware of the facts that can impact the stock's prospects.

Read More
image for news CRISPR Therapeutics AG (CRSP) Is a Trending Stock: Facts to Know Before Betting on It
Crispr Therapeutics: Patience And Opportunity Through Volatility
CRSP
Published: January 14, 2026 by: Seeking Alpha
Sentiment: Positive

Crispr Therapeutics remains highly volatile, disconnected from near-term fundamentals, yet I see long-term value far above current levels. CRSP's business progress is slow, with pipeline milestones and cash runway—not quarterly EPS—being the most relevant metrics for investors. Key risks include the commercial ramp of Casgevy, pipeline execution, and surviving cash burn until anticipated profitability in 2028.

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image for news Crispr Therapeutics: Patience And Opportunity Through Volatility
Investors Heavily Search CRISPR Therapeutics AG (CRSP): Here is What You Need to Know
CRSP
Published: January 13, 2026 by: Zacks Investment Research
Sentiment: Positive

CRISPR Therapeutics (CRSP) has received quite a bit of attention from Zacks.com users lately. Therefore, it is wise to be aware of the facts that can impact the stock's prospects.

Read More
image for news Investors Heavily Search CRISPR Therapeutics AG (CRSP): Here is What You Need to Know
CRISPR Therapeutics AG (CRSP) Presents at 44th Annual J.P. Morgan Healthcare Conference Transcript
CRSP
Published: January 12, 2026 by: Seeking Alpha
Sentiment: Neutral

CRISPR Therapeutics AG (CRSP) Presents at 44th Annual J.P. Morgan Healthcare Conference Transcript

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image for news CRISPR Therapeutics AG (CRSP) Presents at 44th Annual J.P. Morgan Healthcare Conference Transcript
CRISPR Therapeutics (CRSP) Is Considered a Good Investment by Brokers: Is That True?
CRSP
Published: January 12, 2026 by: Zacks Investment Research
Sentiment: Neutral

The recommendations of Wall Street analysts are often relied on by investors when deciding whether to buy, sell, or hold a stock. Media reports about these brokerage-firm-employed (or sell-side) analysts changing their ratings often affect a stock's price.

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image for news CRISPR Therapeutics (CRSP) Is Considered a Good Investment by Brokers: Is That True?
Crispr Therapeutics: Prospects For 2026 - Why I Believe Casgevy Is Key
CRSP
Published: January 02, 2026 by: Seeking Alpha
Sentiment: Positive

Crispr Therapeutics AG commands a $5bn valuation, anchored by Casgevy's commercial approval and robust clinical data in SCD and TDT. Casgevy's slow commercial ramp is expected to accelerate in 2026, with revenue and patient growth as key valuation drivers. CRSP's pipeline—spanning in-vivo, CAR-T, and diabetes assets—offers major upside, but Casgevy remains the only revenue source.

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image for news Crispr Therapeutics: Prospects For 2026 - Why I Believe Casgevy Is Key
Here is What to Know Beyond Why CRISPR Therapeutics AG (CRSP) is a Trending Stock
CRSP
Published: December 30, 2025 by: Zacks Investment Research
Sentiment: Positive

Recently, Zacks.com users have been paying close attention to CRISPR Therapeutics (CRSP). This makes it worthwhile to examine what the stock has in store.

Read More
image for news Here is What to Know Beyond Why CRISPR Therapeutics AG (CRSP) is a Trending Stock
CRISPR Therapeutics AG (CRSP) Stock Falls Amid Market Uptick: What Investors Need to Know
CRSP
Published: December 23, 2025 by: Zacks Investment Research
Sentiment: Negative

In the latest trading session, CRISPR Therapeutics AG (CRSP) closed at $56.46, marking a -2.5% move from the previous day.

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image for news CRISPR Therapeutics AG (CRSP) Stock Falls Amid Market Uptick: What Investors Need to Know
CRSP Stock Rises on Encouraging Early Data From Zugo-Cel Studies
CRSP
Published: December 23, 2025 by: Zacks Investment Research
Sentiment: Positive

CRISPR Therapeutics shares jump after early zugo-cel study data show sustained B-cell depletion and early efficacy across autoimmune and cancer studies.

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image for news CRSP Stock Rises on Encouraging Early Data From Zugo-Cel Studies
CRISPR Therapeutics Provides Broad Update on Zugocaptagene Geleucel (Zugo-cel; formerly CTX112™) in Autoimmune Diseases and Hematologic Malignancies
CRSP
Published: December 22, 2025 by: GlobeNewsWire
Sentiment: Neutral

-Four autoimmune patients treated to date demonstrate deep B-cell depletion sustained for at least 28 days; initial efficacy data suggest significant clinical improvement in patients dosed at the 100 million cell dose, with the first systemic lupus erythematosus (SLE) patient achieving Definitions of Remission in SLE (DORIS) remission through Month 6-

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image for news CRISPR Therapeutics Provides Broad Update on Zugocaptagene Geleucel (Zugo-cel; formerly CTX112™) in Autoimmune Diseases and Hematologic Malignancies
Is Trending Stock CRISPR Therapeutics AG (CRSP) a Buy Now?
CRSP
Published: December 19, 2025 by: Zacks Investment Research
Sentiment: Positive

Recently, Zacks.com users have been paying close attention to CRISPR Therapeutics (CRSP). This makes it worthwhile to examine what the stock has in store.

Read More
image for news Is Trending Stock CRISPR Therapeutics AG (CRSP) a Buy Now?
Why Is CRISPR Therapeutics (CRSP) Up 3.3% Since Last Earnings Report?
CRSP
Published: December 10, 2025 by: Zacks Investment Research
Sentiment: Positive

CRISPR Therapeutics (CRSP) reported earnings 30 days ago. What's next for the stock?

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image for news Why Is CRISPR Therapeutics (CRSP) Up 3.3% Since Last Earnings Report?
CRISPR Therapeutics AG (CRSP) is Attracting Investor Attention: Here is What You Should Know
CRSP
Published: December 08, 2025 by: Zacks Investment Research
Sentiment: Positive

Zacks.com users have recently been watching CRISPR Therapeutics (CRSP) quite a bit. Thus, it is worth knowing the facts that could determine the stock's prospects.

Read More
image for news CRISPR Therapeutics AG (CRSP) is Attracting Investor Attention: Here is What You Should Know
Cathie Wood's Buys And Rumors Aside, Here's Why Crispr Therapeutics Is A Strong Buy
CRSP
Published: December 04, 2025 by: Seeking Alpha
Sentiment: Positive

Crispr Therapeutics AG remains a Strong Buy, driven by forthcoming revenue following Casgevy's FDA/EMA approvals and a robust, expanding pipeline targeting high-value indications. CRSP's commercial launch of Casgevy is progressing, with their share of a $100M+ 2025 total revenue expectation, and significant growth expected into 2026. The pipeline's cardiovascular assets (CTX310/320) show promising early efficacy, with huge addressable markets and the potential to disrupt standard-of-care regimens.

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image for news Cathie Wood's Buys And Rumors Aside, Here's Why Crispr Therapeutics Is A Strong Buy
CRISPR Therapeutics AG (CRSP) Is a Trending Stock: Facts to Know Before Betting on It
CRSP
Published: November 25, 2025 by: Zacks Investment Research
Sentiment: Positive

CRISPR Therapeutics (CRSP) has received quite a bit of attention from Zacks.com users lately. Therefore, it is wise to be aware of the facts that can impact the stock's prospects.

Read More
image for news CRISPR Therapeutics AG (CRSP) Is a Trending Stock: Facts to Know Before Betting on It
4 Struggling Stocks With “Harmless” Pullbacks
APP, CROX, CRSP, PLTR
Published: November 18, 2025 by: Schaeffers Research
Sentiment: Negative

Subscribers to Chart of the Week received this commentary on Sunday, November 16.

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image for news 4 Struggling Stocks With “Harmless” Pullbacks
CRISPR Therapeutics AG (CRSP) is Attracting Investor Attention: Here is What You Should Know
CRSP
Published: November 14, 2025 by: Zacks Investment Research
Sentiment: Positive

Recently, Zacks.com users have been paying close attention to CRISPR Therapeutics (CRSP). This makes it worthwhile to examine what the stock has in store.

Read More
image for news CRISPR Therapeutics AG (CRSP) is Attracting Investor Attention: Here is What You Should Know
CRISPR Therapeutics Post Q3 Earnings: Testing Investor Patience, But Still A Buy
CRSP
Published: November 13, 2025 by: Seeking Alpha
Sentiment: Positive

CRISPR Therapeutics AG remains a pioneering gene editing company, with Casgevy's slow commercial ramp and robust pipeline driving long-term potential. Despite Casgevy's $2.2M list price and broad approvals, revenue growth is gradual due to complex treatment logistics and patient adoption hurdles. CRSP's pipeline includes promising in-vivo cardiovascular, CAR-T oncology/autoimmune, and diabetes programs, with key updates expected in 2025.

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image for news CRISPR Therapeutics Post Q3 Earnings: Testing Investor Patience, But Still A Buy
CRSP Posts Narrower-Than-Expected Loss in Q3, Sales Miss Estimates
CRSP
Published: November 11, 2025 by: Zacks Investment Research
Sentiment: Negative

CRISPR Therapeutics posts a narrower-than-expected Q3 loss, trims R&D spend, and advances late-stage and next-gen gene-editing programs.

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image for news CRSP Posts Narrower-Than-Expected Loss in Q3, Sales Miss Estimates
CRISPR Therapeutics AG (CRSP) Reports Q3 Loss, Lags Revenue Estimates
CRSP
Published: November 10, 2025 by: Zacks Investment Research
Sentiment: Negative

CRISPR Therapeutics AG (CRSP) came out with a quarterly loss of $1.17 per share versus the Zacks Consensus Estimate of a loss of $1.32. This compares to a loss of $1.01 per share a year ago.

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image for news CRISPR Therapeutics AG (CRSP) Reports Q3 Loss, Lags Revenue Estimates
CRISPR Therapeutics AG (CRSP) Is a Trending Stock: Facts to Know Before Betting on It
CRSP
Published: October 31, 2025 by: Zacks Investment Research
Sentiment: Positive

Recently, Zacks.com users have been paying close attention to CRISPR Therapeutics (CRSP). This makes it worthwhile to examine what the stock has in store.

Read More
image for news CRISPR Therapeutics AG (CRSP) Is a Trending Stock: Facts to Know Before Betting on It
Investors Heavily Search CRISPR Therapeutics AG (CRSP): Here is What You Need to Know
CRSP
Published: October 20, 2025 by: Zacks Investment Research
Sentiment: Positive

Recently, Zacks.com users have been paying close attention to CRISPR Therapeutics (CRSP). This makes it worthwhile to examine what the stock has in store.

Read More
image for news Investors Heavily Search CRISPR Therapeutics AG (CRSP): Here is What You Need to Know
Here is What to Know Beyond Why CRISPR Therapeutics AG (CRSP) is a Trending Stock
CRSP
Published: October 07, 2025 by: Zacks Investment Research
Sentiment: Positive

CRISPR Therapeutics (CRSP) has received quite a bit of attention from Zacks.com users lately. Therefore, it is wise to be aware of the facts that can impact the stock's prospects.

Read More
image for news Here is What to Know Beyond Why CRISPR Therapeutics AG (CRSP) is a Trending Stock
CRSP & Sirius Begin Dosing in Thromboembolic Disorder Study in EU
CRSP
Published: September 23, 2025 by: Zacks Investment Research
Sentiment: Neutral

CRISPR Therapeutics and Sirius dose the first patient in a phase II study of SRSD107 for thromboembolic disorders in Europe.

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image for news CRSP & Sirius Begin Dosing in Thromboembolic Disorder Study in EU
Is Trending Stock CRISPR Therapeutics AG (CRSP) a Buy Now?
CRSP
Published: September 23, 2025 by: Zacks Investment Research
Sentiment: Positive

CRISPR Therapeutics (CRSP) has received quite a bit of attention from Zacks.com users lately. Therefore, it is wise to be aware of the facts that can impact the stock's prospects.

Read More
image for news Is Trending Stock CRISPR Therapeutics AG (CRSP) a Buy Now?
CRISPR Therapeutics AG (CRSP) is Attracting Investor Attention: Here is What You Should Know
CRSP
Published: September 12, 2025 by: Zacks Investment Research
Sentiment: Positive

Zacks.com users have recently been watching CRISPR Therapeutics (CRSP) quite a bit. Thus, it is worth knowing the facts that could determine the stock's prospects.

Read More
image for news CRISPR Therapeutics AG (CRSP) is Attracting Investor Attention: Here is What You Should Know
Wall Street Analysts See CRISPR Therapeutics (CRSP) as a Buy: Should You Invest?
CRSP
Published: September 11, 2025 by: Zacks Investment Research
Sentiment: Neutral

Investors often turn to recommendations made by Wall Street analysts before making a Buy, Sell, or Hold decision about a stock. While media reports about rating changes by these brokerage-firm employed (or sell-side) analysts often affect a stock's price, do they really matter?

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image for news Wall Street Analysts See CRISPR Therapeutics (CRSP) as a Buy: Should You Invest?

About CRISPR Therapeutics AG (CRSP)

  • IPO Date 2016-10-19
  • Website https://www.crisprtx.com
  • Industry Biotechnology
  • CEO Samarth Kulkarni
  • Employees 393

CRISPR Therapeutics AG, a gene editing company, focuses on developing gene-based medicines for serious diseases using its proprietary Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) platform. Its CRISPR/Cas9 is a gene editing technology that allows for precise directed changes to genomic DNA. The company has a portfolio of therapeutic programs across a range of disease areas, including hemoglobinopathies, oncology, regenerative medicine, and rare diseases. The company's lead product candidate is CTX001, an ex vivo CRISPR gene-edited therapy for treating patients suffering from transfusion-dependent beta-thalassemia or severe sickle cell disease in which a patient's hematopoietic stem cells are engineered to produce high levels of fetal hemoglobin in red blood cells. It also develops CTX110, a donor-derived gene-edited allogeneic CAR-T investigational therapy targeting cluster of differentiation 19 positive malignancies; CTX120, a donor-derived gene-edited allogeneic CAR-T investigational therapy targeting B-cell maturation antigen for the treatment of relapsed or refractory multiple myeloma; and CTX130, a donor-derived gene-edited allogeneic CAR-T investigational therapy targeting Cluster of Differentiation 70 to treat various solid tumors and hematologic malignancies. In addition, the company develops VCTX210, a gene-edited immune-evasive stem cell-derived product candidate for the treatment of treatment of type 1 diabetes; and pursues various in vivo gene-editing programs that target the liver, lung, muscle, and central nervous system diseases. It has strategic partnerships with Bayer Healthcare LLC, Vertex Pharmaceuticals Incorporated, ViaCyte, Inc., Nkarta, Inc., and Capsida Biotherapeutics. CRISPR Therapeutics AG was incorporated in 2013 and is headquartered in Zug, Switzerland.