ALNY

Alnylam Pharmaceuticals Inc
NASDAQHEALTHCAREBIOTECHNOLOGY

Key Statistics

Market Cap
$31.02B
P/E Ratio
39.09
EPS
$5.93
Beta
0.27
52W High
$495.55
52W Low
$197.81
50-Day MA
$238.41
200-Day MA
$294.30
Dividend Yield
—
Profit Margin
16.10%
Forward P/E
19.68
PEG Ratio
0.33

About Alnylam Pharmaceuticals Inc

Alnylam Pharmaceuticals, Inc., a biopharmaceutical company, focuses on discovering, developing and commercializing RNA interference (RNAi) therapies. The company is headquartered in Cambridge, Massachusetts.

Official WebsiteUSAFY End: December

Fundamentals

Revenue (TTM)$4.80B
Gross Profit (TTM)$3.83B
EBITDA$1.05B
Operating Margin17.90%
Return on Equity96.60%
Return on Assets12.30%
Revenue/Share (TTM)$36.24
Book Value$10.12
Price-to-Book24.87
Price-to-Sales (TTM)6.46
EV/Revenue6.58
EV/EBITDA28.62
Quarterly Earnings Growth (YoY)0.00%
Quarterly Revenue Growth (YoY)66.90%
Shares Outstanding$133.81M
Float$133.22M
% Insiders0.18%
% Institutions101.69%

Historical Volatility

HV 10-Day
33.33%
HV 20-Day
43.69%
HV 30-Day
41.52%
HV 60-Day
82.73%
HV Rank
72.2%

Volatility is currently contracting

Analyst Ratings

Consensus ($368.71 target)
6
Strong Buy
16
Buy
7
Hold

Latest News

Securities Fraud Investigation Into Alnylam Pharmaceuticals, Inc. (ALNY) Continues – Shareholders Who Lost Money Urged To Contact Glancy Prongay Wolke & Rotter LLP, a Leading Securities Fraud Law Firm

LOS ANGELES, Oct. 05, 2026 (GLOBE NEWSWIRE) -- Glancy Prongay Wolke & Rotter LLP, a leading national shareholder rights law firm, continues its investigation on behalf of Alnylam Pharmaceuticals, Inc. (“Alnylam” or the “Company”) (NASDAQ: ALNY) investors concerning the Company's possible violations of the federal securities laws.

GlobeNewsWire10/5/2026Neutral
Alnylam Pharmaceuticals: More Than Meets The Eye After CARDIO-TTRansform

Alnylam Pharmaceuticals, Inc. shares have fallen 18% amid concerns over its ATTR-CM franchise following AstraZeneca/Ionis trial failure. I see pessimism as understandable but overdone; nucresiran's superior TTR knockdown and trial design differences support a credible case for TRITON-CM success. Even if TRITON-CM fails, Amvuttra's first-line share gains and Alnylam's diverse pipeline mitigate downside risk.

Seeking Alpha9/28/2026Negative
Alnylam Highlights AMVUTTRA Momentum, Resets 2026 TTR Revenue Outlook

Alnylam Pharmaceuticals NASDAQ: ALNY highlighted continued momentum for its AMVUTTRA treatment in transthyretin-mediated cardiomyopathy, while outlining a pipeline of upcoming clinical catalysts and discussing changes in the market that prompted a revision to its 2026 TTR franchise revenue outlook.

MarketBeat9/20/2026Positive
Alnylam to Webcast Presentations at Upcoming September Investor Conferences

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), the leading RNAi therapeutics company, announced today that management will present company overviews at the following upcoming investor conferences: Wells Fargo 21st Annual Healthcare Conference on Tuesday, September 8, 2026, at 8:45 AM ET in Everett, Massachusetts Morgan Stanley 24th Annual Global Healthcare Conference on Monday, September 14, 2026, at 10:00 AM ET in New York City A live audio webcast of each pre.

Business Wire9/2/2026Neutral

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Data last updated: 10/17/2026