Agios Pharmaceuticals, Inc. (AGIO)

US — Healthcare Sector
Peers: DNLI  RXRX  BEAM  RCUS  ETNB  COGT  IBRX  GLPG  SRPT  LQDA 

Automate Your Wheel Strategy on AGIO

With Tiblio's Option Bot, you can configure your own wheel strategy including AGIO - and automate your put writes, covered calls, and full wheel strategy. Just connect one of the supported brokerages: tastytrade, Schwab, TradeStation or Tradier and go.

Start Your Free Trial Now

Key Metrics & Ratings

  • symbol AGIO
  • Rev/Share 0.7704
  • Book/Share 22.0906
  • PB 1.0113
  • Debt/Equity 0.0347
  • CurrentRatio 13.8196
  • ROIC -0.3501

 

  • MktCap 1302730560.0
  • FreeCF/Share -7.1224
  • PFCF -3.146
  • PE -3.2368
  • Debt/Assets 0.0321
  • DivYield 0
  • ROE -0.2835

 

  • Rating C
  • Score 2
  • Recommendation Sell
  • P/E Score 1
  • DCF Score 1
  • P/B Score 3
  • D/E Score 3

Recent Analyst Ratings

Type Ticker Analyst Firm Previous Rating Current Rating Previous Price Target Current Price Target Date
Upgrade AGIO Leerink Partners Market Perform Outperform -- $34 Nov. 20, 2025
Downgrade AGIO RBC Capital Mkts Outperform Sector Perform -- $28 Nov. 19, 2025
Initiation AGIO H.C. Wainwright -- Buy -- $58 Feb. 24, 2025
Initiation AGIO Scotiabank -- Sector Outperform -- -- Oct. 16, 2024
Resumed AGIO Raymond James -- Outperform -- $51 Oct. 10, 2024
Downgrade AGIO Leerink Partners Outperform Market Perform $60 $56 Sept. 27, 2024

News

AGIO Stock Hits 52-Week Low on Mixed Sickle Cell Disease Study Results
AGIO
Published: November 20, 2025 by: Zacks Investment Research
Sentiment: Negative

Agios slides to a 52-week low after mixed phase III RISE UP data show a hemoglobin boost but no significant cut in pain crises.

Read More
image for news AGIO Stock Hits 52-Week Low on Mixed Sickle Cell Disease Study Results
Agios Pharmaceuticals, Inc. (AGIO) Discusses Topline Results from RISE UP Phase 3 Trial of Mitapivat in Sickle Cell Disease Transcript
AGIO
Published: November 19, 2025 by: Seeking Alpha
Sentiment: Neutral

Agios Pharmaceuticals, Inc. ( AGIO ) Discusses Topline Results from RISE UP Phase 3 Trial of Mitapivat in Sickle Cell Disease November 19, 2025 8:00 AM EST Company Participants Morgan Sanford Brian Goff - CEO & Director Sarah Gheuens - Chief Medical Officer and Head of Research & Development Tsveta Milanova - Chief Commercial Officer Conference Call Participants Biree Andemariam Eric Schmidt - Cantor Fitzgerald & Co., Research Division Salveen Richter - Goldman Sachs Group, Inc., Research Division Ellen Horste - TD Cowen, Research Division Alec Stranahan - BofA Securities, Research Division Emily Bodnar - H.C. Wainwright & Co, LLC, …

Read More
image for news Agios Pharmaceuticals, Inc. (AGIO) Discusses Topline Results from RISE UP Phase 3 Trial of Mitapivat in Sickle Cell Disease Transcript
AGIO's Q3 Loss Narrower Than Expected, Pyrukynd Drives Y/Y Revenues
AGIO
Published: October 31, 2025 by: Zacks Investment Research
Sentiment: Negative

Agios posts a narrower-than-expected third-quarter loss as Pyrukynd drives a 44% revenue rise, with potential label expansions on the horizon.

Read More
image for news AGIO's Q3 Loss Narrower Than Expected, Pyrukynd Drives Y/Y Revenues
Agios Pharmaceuticals, Inc. (AGIO) Q3 2025 Earnings Call Transcript
AGIO
Published: October 30, 2025 by: Seeking Alpha
Sentiment: Neutral

Agios Pharmaceuticals, Inc. ( AGIO ) Q3 2025 Earnings Call October 30, 2025 8:00 AM EDT Company Participants Morgan Sanford Brian Goff - CEO & Director Cecilia Jones - Chief Financial Officer Tsveta Milanova - Chief Commercial Officer Sarah Gheuens - Chief Medical Officer and Head of Research & Development Conference Call Participants Eric Schmidt - Cantor Fitzgerald & Co., Research Division Alec Stranahan - BofA Securities, Research Division Marc Frahm - TD Cowen, Research Division Tessa Romero - JPMorgan Chase & Co, Research Division Presentation Operator Good morning, and welcome to Agios Pharmaceuticals Third Quarter 2025 Conference Call. [Operator …

Read More
image for news Agios Pharmaceuticals, Inc. (AGIO) Q3 2025 Earnings Call Transcript
INVESTOR ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Agios Pharmaceuticals, Inc. - AGIO
AGIO
Published: October 13, 2025 by: PRNewsWire
Sentiment: Neutral

NEW YORK , Oct. 13, 2025 /PRNewswire/ -- Pomerantz LLP is investigating claims on behalf of investors of Agios Pharmaceuticals, Inc. ("Agios" or the "Company") (NASDAQ: AGIO). Such investors are advised to contact Danielle Peyton at [email protected] or 646-581-9980, ext.

Read More
image for news INVESTOR ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Agios Pharmaceuticals, Inc. - AGIO
INVESTOR ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Agios Pharmaceuticals, Inc. - AGIO
AGIO
Published: October 03, 2025 by: PRNewsWire
Sentiment: Neutral

NEW YORK , Oct. 3, 2025 /PRNewswire/ -- Pomerantz LLP is investigating claims on behalf of investors of Agios Pharmaceuticals, Inc. ("Agios" or the "Company") (NASDAQ: AGIO). Such investors are advised to contact Danielle Peyton at [email protected] or 646-581-9980, ext.

Read More
image for news INVESTOR ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Agios Pharmaceuticals, Inc. - AGIO
INVESTOR ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Agios Pharmaceuticals, Inc. - AGIO
AGIO
Published: September 23, 2025 by: PRNewsWire
Sentiment: Neutral

NEW YORK , Sept. 23, 2025 /PRNewswire/ -- Pomerantz LLP is investigating claims on behalf of investors of Agios Pharmaceuticals, Inc. ("Agios" or the "Company") (NASDAQ: AGIO).

Read More
image for news INVESTOR ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Agios Pharmaceuticals, Inc. - AGIO
INVESTOR ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Agios Pharmaceuticals, Inc. - AGIO
AGIO
Published: September 18, 2025 by: PRNewsWire
Sentiment: Neutral

NEW YORK , Sept. 18, 2025 /PRNewswire/ -- Pomerantz LLP is investigating claims on behalf of investors of Agios Pharmaceuticals, Inc. ("Agios" or the "Company") (NASDAQ: AGIO).

Read More
image for news INVESTOR ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Agios Pharmaceuticals, Inc. - AGIO
INVESTOR ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Agios Pharmaceuticals, Inc. – AGIO
AGIO
Published: September 10, 2025 by: GlobeNewsWire
Sentiment: Neutral

NEW YORK, Sept. 10, 2025 (GLOBE NEWSWIRE) -- Pomerantz LLP is investigating claims on behalf of investors of Agios Pharmaceuticals, Inc. (“Agios” or the “Company”) (NASDAQ: AGIO). Such investors are advised to contact Danielle Peyton at [email protected] or 646-581-9980, ext. 7980.

Read More
image for news INVESTOR ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Agios Pharmaceuticals, Inc. – AGIO
INVESTOR ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Agios Pharmaceuticals, Inc. - AGIO
AGIO
Published: September 08, 2025 by: PRNewsWire
Sentiment: Neutral

NEW YORK , Sept. 8, 2025 /PRNewswire/ -- Pomerantz LLP is investigating claims on behalf of investors of Agios Pharmaceuticals, Inc. ("Agios" or the "Company") (NASDAQ: AGIO).

Read More
image for news INVESTOR ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Agios Pharmaceuticals, Inc. - AGIO
Agios Pharmaceuticals: Why A Delayed FDA Review Could Still Be A Positive
AGIO
Published: September 08, 2025 by: Seeking Alpha
Sentiment: Positive

Agios faces a pivotal FDA decision on 7 December for mitapivat's thalassemia expansion, with a good chance of approval based on strong Phase 3 data. The stock has lagged typical pre-PDUFA momentum, offering an attractive entry point for risk-tolerant investors ahead of a potential catalyst. Safety concerns exist but are likely manageable with enhanced monitoring; Agios' robust cash position provides a buffer against regulatory setbacks.

Read More
image for news Agios Pharmaceuticals: Why A Delayed FDA Review Could Still Be A Positive
AGIO Stock Falls as FDA Delays Decision on Pyrukynd for Thalassemia
AGIO
Published: September 05, 2025 by: Zacks Investment Research
Sentiment: Negative

Agios shares tank as the FDA extends the review period for Pyrukynd in thalassemia by three months, pushing the final ruling to Dec. 7, 2025.

Read More
image for news AGIO Stock Falls as FDA Delays Decision on Pyrukynd for Thalassemia
Agios Pharmaceuticals: New FDA Setback Likely Temporary As Issues Can Be Mitigated
AGIO
Published: September 04, 2025 by: Seeking Alpha
Sentiment: Neutral

Agios Pharmaceuticals, Inc. faces a three-month FDA review delay for mitapivat in thalassemia due to safety concerns, but no new efficacy or safety data was requested. Despite the setback, I remain confident in mitapivat's strong efficacy and competitive oral profile, expecting eventual FDA approval in December. Agios is financially robust with $1.3bn cash, and approval could unlock blockbuster revenues and a significant share price upside for investors.

Read More
image for news Agios Pharmaceuticals: New FDA Setback Likely Temporary As Issues Can Be Mitigated
Agios to Host Webcast Conference Call of Second Quarter Financial Results on July 31, 2025 at 8:00am ET
AGIO
Published: July 14, 2025 by: GlobeNewsWire
Sentiment: Neutral

CAMBRIDGE, Mass., July 14, 2025 (GLOBE NEWSWIRE) -- Agios Pharmaceuticals, Inc. (Nasdaq: AGIO), a leader in cellular metabolism and pyruvate kinase (PK) activation pioneering therapies for rare diseases, today announced the company will host a conference call and live webcast on Thursday, July 31, 2025, at 8:00 a.m.

Read More
image for news Agios to Host Webcast Conference Call of Second Quarter Financial Results on July 31, 2025 at 8:00am ET
Agios to Highlight Pyruvate Kinase Activation Portfolio with New Data in Rare Blood Disorders at 30th EHA Congress
AGIO
Published: May 14, 2025 by: GlobeNewsWire
Sentiment: Neutral

CAMBRIDGE, Mass., May 14, 2025 (GLOBE NEWSWIRE) -- Agios Pharmaceuticals, Inc. (Nasdaq: AGIO), a leader in cellular metabolism and pyruvate kinase (PK) activation pioneering therapies for rare diseases, today announced that new data on the company's PK activators, mitapivat and tebapivat, will be featured in oral and poster presentations during the 30th European Hematology Association (EHA) Congress (EHA 2025) in Milan, Italy, June 12-15, 2025.

Read More
image for news Agios to Highlight Pyruvate Kinase Activation Portfolio with New Data in Rare Blood Disorders at 30th EHA Congress
Agios to Present at the 2025 RBC Capital Markets Global Healthcare Conference on May 21, 2025
AGIO
Published: May 09, 2025 by: GlobeNewsWire
Sentiment: Neutral

CAMBRIDGE, Mass., May 09, 2025 (GLOBE NEWSWIRE) -- Agios Pharmaceuticals, Inc. (Nasdaq: AGIO), a leader in cellular metabolism and PK activation pioneering therapies for rare diseases, today announced that its management team is scheduled to present at the 2025 RBC Capital Markets Global Healthcare Conference on Wednesday, May 21, 2025, at 8:00 am ET.

Read More
image for news Agios to Present at the 2025 RBC Capital Markets Global Healthcare Conference on May 21, 2025
Agios Pharmaceuticals, Inc. (AGIO) Q1 2025 Earnings Call Transcript
AGIO
Published: May 01, 2025 by: Seeking Alpha
Sentiment: Neutral

Agios Pharmaceuticals, Inc. (NASDAQ:AGIO ) Q1 2025 Earnings Conference Call May 1, 2025 8:00 AM ET Company Participants Chris Taylor – Vice President-Investor Relations and Corporate Communications Brian Goff – Chief Executive Officer Sarah Gheuens – Chief Medical Officer, Head-Research and Development Tsveta Milanova – Chief Commercial Officer Cecilia Jones – Chief Financial Officer Conference Call Participants Gregory Renza – RBC Capital Markets Alec Stranahan – Bank of America Divya Rao – TD Cowen Hiro Nagayumi – Cantor Emily Bodnar – H.C. Wainwright Tessa Romero – JPMorgan Operator Good morning, and welcome to Agios' First Quarter 2025 Conference Call.

Read More
image for news Agios Pharmaceuticals, Inc. (AGIO) Q1 2025 Earnings Call Transcript
Agios Pharmaceuticals (AGIO) Reports Q1 Loss, Misses Revenue Estimates
AGIO
Published: May 01, 2025 by: Zacks Investment Research
Sentiment: Negative

Agios Pharmaceuticals (AGIO) came out with a quarterly loss of $1.55 per share versus the Zacks Consensus Estimate of a loss of $1.80. This compares to loss of $1.45 per share a year ago.

Read More
image for news Agios Pharmaceuticals (AGIO) Reports Q1 Loss, Misses Revenue Estimates
Agios Reports First Quarter 2025 Financial Results and Recent Business Highlights
AGIO
Published: May 01, 2025 by: GlobeNewsWire
Sentiment: Neutral

– U.S. Regulatory Filing Under Active Review for Approval of PYRUKYND ® (mitapivat) in Thalassemia, with PDUFA Goal Date of September 7, 2025 – – Phase 3 RISE UP Study of Mitapivat in Sickle Cell Disease On Track, with Topline Results Expected in Late 2025; Potential U.S. Commercial Launch in 2026 – – Tebapivat Advancing in Clinical Trials for Lower-Risk Myelodysplastic Syndromes (LR-MDS) and Sickle Cell Disease – – PYRUKYND Net Revenue of $8.7 Million in Q1; Cash, Cash Equivalents and Marketable Securities of $1.4 Billion as of March 31, 2025 – CAMBRIDGE, Mass., May 01, 2025 (GLOBE NEWSWIRE) -- …

Read More
image for news Agios Reports First Quarter 2025 Financial Results and Recent Business Highlights
New Strong Sell Stocks for April 3rd
AGIO, CHGG, EFX
Published: April 03, 2025 by: Zacks Investment Research
Sentiment: Negative

AGIO, CHGG and EFX have been added to the Zacks Rank #5 (Strong Sell) List on April 3, 2025.

Read More
image for news New Strong Sell Stocks for April 3rd
Agios to Present at the TD Cowen 45th Annual Healthcare Conference on March 3, 2025
AGIO
Published: February 20, 2025 by: GlobeNewsWire
Sentiment: Neutral

CAMBRIDGE, Mass., Feb. 20, 2025 (GLOBE NEWSWIRE) -- Agios Pharmaceuticals, Inc. (Nasdaq: AGIO), a leader in cellular metabolism and PK activation pioneering therapies for rare diseases, today announced that its management team is scheduled to present at the TD Cowen 45th Annual Healthcare Conference on Monday, March 3, 2025, at 10:30 a.m. ET.

Read More
image for news Agios to Present at the TD Cowen 45th Annual Healthcare Conference on March 3, 2025
Agios Pharmaceuticals, Inc. (AGIO) Q4 2024 Earnings Call Transcript
AGIO
Published: February 13, 2025 by: Seeking Alpha
Sentiment: Neutral

Agios Pharmaceuticals, Inc. (NASDAQ:AGIO ) Q4 2024 Earnings Conference Call February 13, 2025 8:00 AM ET Company Participants Brian Goff - CEO Sarah Gheuens - CMO & Head OF R&D Tsveta Milanova - CCO Cecilia Jones - CFO Chris Taylor - VP, IR & Corporate Communications Conference Call Participants Eric Schmidt - Cantor Fitzgerald Divya Rao - TD Cowen Gregory Renza - RBC Capital Markets Greg Harrison - Scotiabank Chris Raymond - Piper Sandler Alec Stranahan - Bank of America Lydia Erdman - Goldman Sachs Tessa Romero - J.P. Morgan Operator Good morning, and welcome to Agios' fourth quarter 2024 …

Read More
image for news Agios Pharmaceuticals, Inc. (AGIO) Q4 2024 Earnings Call Transcript
Agios Pharmaceuticals (AGIO) Reports Q4 Loss, Tops Revenue Estimates
AGIO
Published: February 13, 2025 by: Zacks Investment Research
Sentiment: Negative

Agios Pharmaceuticals (AGIO) came out with a quarterly loss of $1.74 per share versus the Zacks Consensus Estimate of a loss of $1.73. This compares to loss of $1.72 per share a year ago.

Read More
image for news Agios Pharmaceuticals (AGIO) Reports Q4 Loss, Tops Revenue Estimates

About Agios Pharmaceuticals, Inc. (AGIO)

  • IPO Date 2013-07-24
  • Website https://www.agios.com
  • Industry Biotechnology
  • CEO Brian M. Goff
  • Employees 486

Agios Pharmaceuticals, Inc., a biopharmaceutical company, engages in the discovery and development of medicines in the field of cellular metabolism and adjacent areas of biology. The company offers PYRUKYND (mitapivat) an activator of both wild-type and a variety of mutant pyruvate kinase, PK, enzymes for the treatment of hemolytic anemias; and AG-946 that is in Phase I clinical study for treating hemolytic anemias and other indications. Agios Pharmaceuticals, Inc. was incorporated in 2007 and is headquartered in Cambridge, Massachusetts.