AGEN

Agenus Inc
NASDAQHEALTHCAREBIOTECHNOLOGY

Key Statistics

Market Cap
$322.91M
P/E Ratio
2.54
EPS
$2.81
Beta
1.52
52W High
$10.31
52W Low
$2.71
50-Day MA
$7.46
200-Day MA
$5.01
Dividend Yield
—
Profit Margin
30.80%
Forward P/E
3.73
PEG Ratio
1.44

About Agenus Inc

Agenus Inc., a clinical-stage immuno-oncology company, discovers and develops immuno-oncology products in the United States and internationally. The company is headquartered in Lexington, Massachusetts.

Official WebsiteUSAFY End: December

Fundamentals

Revenue (TTM)$133.95M
Gross Profit (TTM)$202.82M
EBITDA$54.36M
Operating Margin36.20%
Return on Equity-1279.00%
Return on Assets13.60%
Revenue/Share (TTM)$3.03
Book Value$-2.33
Price-to-Book218.61
Price-to-Sales (TTM)2.41
EV/Revenue2.354
EV/EBITDA2.00
Quarterly Earnings Growth (YoY)-99.00%
Quarterly Revenue Growth (YoY)4.10%
Shares Outstanding$45.16M
Float$40.43M
% Insiders6.27%
% Institutions44.87%

Historical Volatility

HV 10-Day
96.16%
HV 20-Day
87.83%
HV 30-Day
104.69%
HV 60-Day
93.56%
HV Rank
—

Volatility is currently contracting

Analyst Ratings

Consensus ($26.33 target)
3
Buy

Latest News

Agenus Reports More Than Half of Patients with Refractory MSS Metastatic Colorectal Cancer Achieved Long-Term Survival Following BOT+BAL Treatment at SITC 2026

LEXINGTON, Mass.--(BUSINESS WIRE)---- $AGEN #Botensilimab--Agenus Inc. (Nasdaq: AGEN), a leader in immuno-oncology innovation, today announced new findings from a long-term survivor analysis of its Phase 1b C-800-01 trial evaluating botensilimab (BOT), a multifunctional, Fc-enhanced anti-CTLA-4 antibody, in combination with balstilimab (BAL), an anti-PD-1 antibody, in heavily pretreated patients with microsatellite-stable (MSS) metastatic colorectal cancer (mCRC) without active liver metastases. The results were prese.

Business Wire11/6/2026Neutral
Agenus Reports Third Quarter 2026 Results, Highlighted by First Marketing Authorizations for BOT+BAL and Global Investigator Support for Phase 3 ROBBIN Study

LEXINGTON, Mass.--(BUSINESS WIRE)---- $AGEN #Armenia--Agenus Inc. (Nasdaq: AGEN), a leader in immuno-oncology innovation, today reported financial results for the third quarter ended September 30, 2026, and highlighted progress preparing its global randomized Phase 3 ROBBIN trial of botensilimab (BOT), a multifunctional, Fc-enhanced anti-CTLA-4 antibody, plus balstilimab (BAL), an anti-PD-1 antibody, before surgery in patients with high-risk Stage II and Stage III microsatellite-stable (MSS) colon cancer. The cli.

Business Wire11/5/2026Neutral
Agenus Announces Nature Medicine Publication of Multicenter UNICORN Phase 2 Trial Demonstrating Deep Responses with Neoadjuvant BOT+BAL in Resectable Colon Cancer

LEXINGTON, Mass.--(BUSINESS WIRE)---- $AGEN #AGEN--Agenus Inc. (Nasdaq: AGEN), a leader in immuno-oncology innovation, today announced the peer-reviewed publication of results from the investigator-sponsored, multicenter Phase 2 UNICORN trial evaluating short-course preoperative, or neoadjuvant, botensilimab (BOT), Agenus' multifunctional, Fc-enhanced anti-CTLA-4 antibody, alone or in combination with balstilimab (BAL), Agenus' anti-PD-1 antibody, in patients with resectable, locally advanced colon cancer. The.

Business Wire11/2/2026Neutral
Agenus Pivots BOT/BAL Strategy to Phase III Colon Cancer Trial

Agenus NASDAQ: AGEN is concentrating its registration strategy for BOT/BAL on the Phase III ROBBIN trial in neoadjuvant high-risk stage II and III microsatellite-stable (MSS) colon cancer, after ending funding for its BATTMAN study in later-line metastatic disease.

MarketBeat10/20/2026Neutral
Agenus to Present Three-Year Overall Survival Data for BOT+BAL in Recurrent Ovarian Cancer at IGCS 2026

LEXINGTON, Mass.--(BUSINESS WIRE)--Agenus Inc. (Nasdaq: AGEN), a leader in immuno-oncology innovation, today announced that a poster evaluating botensilimab (BOT), an Fc-enhanced multifunctional anti-CTLA-4 antibody, in combination with balstilimab (BAL), an anti-PD-1 antibody, has been accepted for presentation at the International Gynecologic Cancer Society (IGCS) Annual Global Meeting, taking place October 1–3, 2026, in Montreal, Canada. The presentation will feature results from the recurre.

Business Wire9/10/2026Neutral
Agenus to Participate in Upcoming September Investor Conferences

LEXINGTON, Mass.--(BUSINESS WIRE)---- $AGEN #BOT--Agenus Inc. (Nasdaq: AGEN), a leader in immuno-oncology innovation, today announced that Robin Taylor, Ph.D., Chief Commercial Officer, and Zack Armen, Head of Corporate Development and Investor Relations, will participate in fireside chats and one-on-one investor meetings at two upcoming investor conferences in September. Cantor Global Healthcare Conference 2026 September 9 -11, 2026; New York, NY Fireside Chat: Tuesday, September 8, 2026 | 11:30 a.m-12:00 p.

Business Wire8/31/2026Neutral
Agenus Reports Second Quarter 2026 Results and Advances Phase 3 ROBBIN Trial of BOT+BAL in Neoadjuvant MSS Colon Cancer

LEXINGTON, Mass.--(BUSINESS WIRE)---- $AGEN #BOT--Agenus Inc. (Nasdaq: AGEN), a leader in immuno-oncology innovation, today reported financial results for the second quarter ended June 30, 2026, and provided an update on its financing-supported strategy to advance botensilimab (BOT), a multifunctional, Fc-enhanced anti-CTLA-4 antibody, plus balstilimab (BAL), an anti-PD-1 antibody, in a curative-intent treatment setting before surgery in high-risk, resectable microsatellite-stable (MSS) colon cancer. As previ.

Business Wire8/6/2026Neutral

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Data last updated: 11/7/2026