Alnylam Pharmaceuticals, Inc. (ALNY)

US — Healthcare Sector
Peers: ARWR  BMRN  INCY  IONS  APLS  SRPT  AGIO 

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Key Metrics & Ratings

  • symbol ALNY
  • Rev/Share 18.9855
  • Book/Share 1.9324
  • PB 235.9712
  • Debt/Equity 5.176
  • CurrentRatio 2.801
  • ROIC -0.0457

 

  • MktCap 59772030840.0
  • FreeCF/Share -0.4017
  • PFCF -1147.5202
  • PE -185.3159
  • Debt/Assets 0.2841
  • DivYield 0
  • ROE -2.7421

 

  • Rating C-
  • Score 1
  • Recommendation Strong Sell
  • P/E Score 1
  • DCF Score 3
  • P/B Score 1
  • D/E Score 1

Recent Analyst Ratings

Type Ticker Analyst Firm Previous Rating Current Rating Previous Price Target Current Price Target Date
Upgrade ALNY Wolfe Research Underperform Peer Perform -- -- Aug. 4, 2025
Upgrade ALNY Oppenheimer Perform Outperform -- $490 Aug. 4, 2025
Resumed ALNY Raymond James -- Outperform -- $370 July 30, 2025
Initiation ALNY Truist -- Buy -- $385 July 21, 2025
Initiation ALNY Redburn Atlantic -- Buy -- $353 March 31, 2025
Upgrade ALNY JP Morgan Neutral Overweight $280 $328 March 24, 2025
Initiation ALNY Scotiabank -- Sector Outperform -- -- Oct. 16, 2024
Upgrade ALNY Goldman Neutral Buy $198 $370 Aug. 16, 2024

News

Alnylam: Waiting For Regulatory Updates In March
ALNY
Published: February 13, 2025 by: Seeking Alpha
Sentiment: Positive

Alnylam's Amvuttra and partner Sanofi's fitusiran have PDUFA dates with the FDA next month, and approvals should create new revenue sources for the company. Alnylam's 2025 guidance for the TTR franchise implies modest growth acceleration compared to 2024, driven by Amvuttra's expected approval next month. Fitusiran's approval could result in meaningful annual royalties for Alnylam from partner Sanofi, enhancing long-term profitability and cash flows.

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image for news Alnylam: Waiting For Regulatory Updates In March
ILMN vs. ALNY: Which Stock Is the Better Value Option?
ALNY, ILMN
Published: February 11, 2025 by: Zacks Investment Research
Sentiment: Neutral

Investors with an interest in Medical - Biomedical and Genetics stocks have likely encountered both Illumina (ILMN) and Alnylam Pharmaceuticals (ALNY). But which of these two stocks offers value investors a better bang for their buck right now?

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image for news ILMN vs. ALNY: Which Stock Is the Better Value Option?
Will These 5 Biotech Bigwig Stocks Surpass Q4 Earnings Forecast?
ALNY, BIIB, GILD, MRNA, VRTX
Published: February 10, 2025 by: Zacks Investment Research
Sentiment: Positive

We focus on biotech stocks like VRTX, GILD, BIIB, ALNY and MRNA, which are scheduled to report this week.

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image for news Will These 5 Biotech Bigwig Stocks Surpass Q4 Earnings Forecast?

About Alnylam Pharmaceuticals, Inc. (ALNY)

  • IPO Date 2004-06-01
  • Website https://www.alnylam.com
  • Industry Biotechnology
  • CEO Yvonne L. Greenstreet
  • Employees 2230

Alnylam Pharmaceuticals, Inc., a biopharmaceutical company, focuses on discovering, developing, and commercializing novel therapeutics based on ribonucleic acid interference. The company's pipeline of investigational RNAi therapeutics focuses on genetic medicines, cardio-metabolic diseases, hepatic infectious diseases, and central nervous system (CNS)/ocular diseases. Its marketed products include ONPATTRO (patisiran), a lipid complex injection for the treatment of the polyneuropathy of hereditary transthyretin-mediated amyloidosis in adults; GIVLAARI for the treatment of adults with acute hepatic porphyria (AHP); and OXLUMO (lumasiran) for the treatment of primary hyperoxaluria type 1 (PH1). In addition, the company is developing givosiran for the treatment of adolescent patients with AHP; patisiran for the treatment of transthyretin amyloidosis, or ATTR amyloidosis, with cardiomyopathy; cemdisiran to treat complement-mediated diseases; ALN-AAT02 for the treatment of AAT deficiency-associated liver disease; ALN-HBV02 to treat chronic HBV infection; Zilebesiran to treat hypertension; and ALN-HSD to treat NASH. Further, it offers Fitusiran for the treatment of hemophilia and rare bleeding disorders, Inclisiran to treat hypercholesterolemia, lumasiran for the treatment of advanced PH1 and recurrent renal stones, and vutrisiran for the treatment of ATTR amyloidosis, which is in phase 3 clinical trial. Alnylam Pharmaceuticals, Inc. has strategic collaborations with Regeneron Pharmaceuticals, Inc. to discover, develop, and commercialize RNAi therapeutics for a range of diseases by addressing therapeutic targets expressed in the eye and CNS; and Sanofi Genzyme to discover, develop, and commercialize RNAi therapeutics. It also has license and collaboration agreements with Novartis AG; Vir Biotechnology, Inc.; Dicerna Pharmaceuticals, Inc.; Ionis Pharmaceuticals, Inc.; and PeptiDream, Inc. The company was founded in 2002 and is headquartered in Cambridge, Massachusetts.