Sarepta Therapeutics, Inc. (SRPT)

US — Healthcare Sector
Peers: RXRX  AGIO  BEAM  COGT  DNLI  ETNB  RCUS  ADPT  IBRX  MLYS 

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Key Metrics & Ratings

  • symbol SRPT
  • Rev/Share 24.0801
  • Book/Share 13.17
  • PB 1.5399
  • Debt/Equity 0.947
  • CurrentRatio 2.9545
  • ROIC -0.0492

 

  • MktCap 2125080360.0
  • FreeCF/Share -3.8792
  • PFCF -5.4652
  • PE -7.4869
  • Debt/Assets 0.3579
  • DivYield 0
  • ROE -0.2031

 

  • Rating C+
  • Score 2
  • Recommendation Sell
  • P/E Score 1
  • DCF Score 5
  • P/B Score 4
  • D/E Score 1

Recent Analyst Ratings

Type Ticker Analyst Firm Previous Rating Current Rating Previous Price Target Current Price Target Date
Resumed SRPT Barclays -- Equal Weight -- $20 Jan. 28, 2026
Initiation SRPT Wedbush -- Outperform -- $32 Dec. 9, 2025
Upgrade SRPT Mizuho Neutral Outperform -- $26 Nov. 5, 2025
Upgrade SRPT BMO Capital Markets Market Perform Outperform -- $50 Sept. 22, 2025
Upgrade SRPT JP Morgan Underweight Neutral -- $24 July 29, 2025
Upgrade SRPT Oppenheimer Perform Outperform -- $37 July 29, 2025
Upgrade SRPT Barclays Underweight Equal Weight -- $22 July 29, 2025
Initiation SRPT Bernstein -- Market Perform -- $13 July 29, 2025
Reiterated SRPT H.C. Wainwright -- Sell -- $5 July 29, 2025
Downgrade SRPT Barclays Equal Weight Underweight -- $10 July 28, 2025

News

SRPT Stock Up 8% on Positive Long-Term Data From Elevidys Study in DMD
SRPT
Published: January 27, 2026 by: Zacks Investment Research
Sentiment: Positive

SRPT jumps nearly 8% after Elevidys shows sustained motor gains and slower progression three years post-dose in the phase III EMBARK DMD study.

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image for news SRPT Stock Up 8% on Positive Long-Term Data From Elevidys Study in DMD
Sarepta Therapeutics, Inc. (SRPT) Discusses 3-Year Topline Results From EMBARK Phase 3 Trial of ELEVIDYS in Duchenne Muscular Dystrophy Transcript
SRPT
Published: January 26, 2026 by: Seeking Alpha
Sentiment: Neutral

Sarepta Therapeutics, Inc. (SRPT) Discusses 3-Year Topline Results From EMBARK Phase 3 Trial of ELEVIDYS in Duchenne Muscular Dystrophy Transcript

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image for news Sarepta Therapeutics, Inc. (SRPT) Discusses 3-Year Topline Results From EMBARK Phase 3 Trial of ELEVIDYS in Duchenne Muscular Dystrophy Transcript
Sarepta Therapeutics (SRPT) Upgraded to Buy: What Does It Mean for the Stock?
SRPT
Published: January 26, 2026 by: Zacks Investment Research
Sentiment: Positive

Sarepta Therapeutics (SRPT) might move higher on growing optimism about its earnings prospects, which is reflected by its upgrade to a Zacks Rank #2 (Buy).

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image for news Sarepta Therapeutics (SRPT) Upgraded to Buy: What Does It Mean for the Stock?
Sarepta Therapeutics shares rise on positive Duchenne gene therapy data
SRPT
Published: January 26, 2026 by: Proactive Investors
Sentiment: Positive

Sarepta Therapeutics Inc (NASDAQ:SRPT) shares moved higher in early trade on Monday as it reported positive topline three-year results from its Phase 3 EMBARK study evaluating its gene therapy ELEVIDYS in ambulatory patients with Duchenne muscular dystrophy. Sarepta said patients treated with ELEVIDYS demonstrated statistically significant and clinically meaningful slowing of disease progression across key functional measures compared with an untreated external control group.

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image for news Sarepta Therapeutics shares rise on positive Duchenne gene therapy data
Sarepta Therapeutics: Is Elevidys A Bust?
SRPT
Published: January 16, 2026 by: Seeking Alpha
Sentiment: Negative

Sarepta Therapeutics remains highly volatile as ELEVIDYS sales drive sentiment, with Q4 revenue missing expectations and safety concerns lingering. Despite fading ELEVIDYS sales, SRPT management reiterates a $500M annual revenue floor and expects normalization in ambulatory demand to support growth. SRPT fundamentals are robust, with nearly $1B in cash, no near-term debt, and a stable PMO franchise generating almost $1B in 2025 revenue.

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image for news Sarepta Therapeutics: Is Elevidys A Bust?
Sarepta Therapeutics, Inc. (SRPT) Presents at 44th Annual J.P. Morgan Healthcare Conference Transcript
SRPT
Published: January 12, 2026 by: Seeking Alpha
Sentiment: Neutral

Sarepta Therapeutics, Inc. (SRPT) Presents at 44th Annual J.P. Morgan Healthcare Conference Transcript

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image for news Sarepta Therapeutics, Inc. (SRPT) Presents at 44th Annual J.P. Morgan Healthcare Conference Transcript
Sarepta Reports Preliminary* Fourth Quarter and Full-Year 2025 Net Product Revenues
SRPT
Published: January 12, 2026 by: Business Wire
Sentiment: Neutral

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Sarepta Therapeutics, Inc. (NASDAQ:SRPT), the leader in precision genetic medicine for rare diseases, today reports preliminary* fourth quarter and full-year 2025 net product revenues and cash, cash equivalents, restricted cash and investments on hand as of December 31, 2025, as part of its presentation today at the 44th Annual J.P. Morgan Healthcare Conference in San Francisco, California. Financial Update* (preliminary and unaudited) Total net product revenu.

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image for news Sarepta Reports Preliminary* Fourth Quarter and Full-Year 2025 Net Product Revenues
Johnson Fistel Investigates Sarepta Therapeutics, Inc. (SRPT) Directors for Potential Breaches of Fiduciary Duty
SRPT
Published: January 12, 2026 by: Newsfile Corp
Sentiment: Neutral

San Diego, California--(Newsfile Corp. - January 12, 2026) - Shareholder rights law firm Johnson Fistel, PLLP is investigating potential shareholder derivative claims on behalf of Sarepta Therapeutics, Inc. (NASDAQ: SRPT) concerning whether certain officers and directors breached their fiduciary duties to the Company and its shareholders. The investigation follows the filing of a securities class action involving purchases of Sarepta securities between June 22, 2023 and June 24, 2025 (the "Class Period").

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image for news Johnson Fistel Investigates Sarepta Therapeutics, Inc. (SRPT) Directors for Potential Breaches of Fiduciary Duty
Why Is Sarepta Therapeutics (SRPT) Up 26.4% Since Last Earnings Report?
SRPT
Published: December 03, 2025 by: Zacks Investment Research
Sentiment: Positive

Sarepta Therapeutics (SRPT) reported earnings 30 days ago. What's next for the stock?

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image for news Why Is Sarepta Therapeutics (SRPT) Up 26.4% Since Last Earnings Report?
Sarepta's Stock Rises on Positive Updates on DM1 Therapy
SRPT
Published: November 25, 2025 by: Zacks Investment Research
Sentiment: Positive

SRPT's stock jumps as its SRP-1003 study advances with a positive safety review and new dosing cohorts underway.

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image for news Sarepta's Stock Rises on Positive Updates on DM1 Therapy
INVESTOR ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Sarepta Therapeutics, Inc. - SRPT
SRPT
Published: November 20, 2025 by: PRNewsWire
Sentiment: Neutral

NEW YORK , Nov. 20, 2025 /PRNewswire/ -- Pomerantz LLP is investigating claims on behalf of investors of Sarepta Therapeutics, Inc. ("Sarepta" or the "Company") (NASDAQ: SRPT). Such investors are advised to contact Danielle Peyton at [email protected] or 646-581-9980, ext.

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image for news INVESTOR ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Sarepta Therapeutics, Inc. - SRPT
FDA Restricts Use of Sarepta's Gene Therapy, Adds Safety Warnings
SRPT
Published: November 17, 2025 by: Zacks Investment Research
Sentiment: Neutral

SRPT's Elevidys gets a sharply narrowed FDA label with new liver safety warnings that reshape how the gene therapy can be used.

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image for news FDA Restricts Use of Sarepta's Gene Therapy, Adds Safety Warnings
Sarepta Announces FDA's Approval of Updated ELEVIDYS Prescribing Information
SRPT
Published: November 14, 2025 by: Business Wire
Sentiment: Neutral

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Sarepta Therapeutics, Inc. (NASDAQ:SRPT), the leader in precision genetic medicine for rare diseases, today announced an update to the prescribing information for ELEVIDYS (delandistrogene moxeparvovec-rokl), the only approved gene therapy for Duchenne muscular dystrophy (DMD). As previously disclosed, the ELEVIDYS label now includes several key updates, including: A boxed warning for the risk of acute serious liver injury (ALI) and acute liver failure (ALF).

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image for news Sarepta Announces FDA's Approval of Updated ELEVIDYS Prescribing Information
US FDA adds strongest warning to Sarepta gene therapy after fatal liver injuries
SRPT
Published: November 14, 2025 by: Reuters
Sentiment: Negative

The U.S. Food and Drug Administration said on Friday it approved new labeling for Sarepta Therapeutics' gene therapy Elevidys that includes its most serious safety warning and restricts use of the treatment to walking patients with Duchenne muscular dystrophy.

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image for news US FDA adds strongest warning to Sarepta gene therapy after fatal liver injuries
SRPT Q3 Earnings Miss Estimates, Stock Dips on DMD Study Failure
SRPT
Published: November 04, 2025 by: Zacks Investment Research
Sentiment: Negative

Sarepta's Q3 loss and the failure of its key DMD study sent shares tumbling, clouding hopes for its PMO therapies and gene therapy Elevidys.

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image for news SRPT Q3 Earnings Miss Estimates, Stock Dips on DMD Study Failure
Sarepta Therapeutics: Why High Risk, Low Return Until Mid-To-Late 2026
SRPT
Published: November 04, 2025 by: Seeking Alpha
Sentiment: Negative

Sarepta Therapeutics, Inc. faces uncertainty after Elevidys' revenue decline and ESSENCE trial failure, leading to a 25% SRPT stock drop. SRPT's PMO franchise remains its cash engine, but regulatory reliance on real-world evidence and FDA unpredictability add risk to the investment thesis. Label contraction for Elevidys and margin pressures weigh on near-term outlook, with upside catalysts mostly expected in 2026 from RNA therapeutics data.

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image for news Sarepta Therapeutics: Why High Risk, Low Return Until Mid-To-Late 2026
Sarepta Therapeutics Stock Tumbles After Trial Data
SRPT
Published: November 04, 2025 by: Schaeffers Research
Sentiment: Negative

Sarepta Pharmaceuticals Inc (NASDAQ: SRPT) stock is plummeting down, down 31.4% at $16.77 at last glance.

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image for news Sarepta Therapeutics Stock Tumbles After Trial Data
Sarepta Therapeutics (SRPT) Reports Q3 Earnings: What Key Metrics Have to Say
SRPT
Published: November 04, 2025 by: Zacks Investment Research
Sentiment: Neutral

While the top- and bottom-line numbers for Sarepta Therapeutics (SRPT) give a sense of how the business performed in the quarter ended September 2025, it could be worth looking at how some of its key metrics compare to Wall Street estimates and year-ago values.

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image for news Sarepta Therapeutics (SRPT) Reports Q3 Earnings: What Key Metrics Have to Say
Sarepta Therapeutics: A Discounted Valuation Meets Breakthrough Pipeline
SRPT
Published: October 10, 2025 by: Seeking Alpha
Sentiment: Positive

Sarepta Therapeutics is showing signs of recovery, driven by its robust pipeline and recent revenue growth, despite past clinical setbacks. SRPT's near-term catalyst is SRP-9003, a gene therapy for Limb-Girdle Muscular Dystrophy, with pivotal Phase 3 data expected in late 2025 or early 2026. Valuation remains attractive, with SRPT trading at a discount to peers and holding a strong cash position, while upcoming data could drive significant upside.

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image for news Sarepta Therapeutics: A Discounted Valuation Meets Breakthrough Pipeline
What's Going On Sarepta Stock On Wednesday?
SRPT
Published: October 08, 2025 by: Benzinga
Sentiment: Neutral

Sarepta Therapeutics Inc. (NASDAQ:SRPT) stock is trading higher on Wednesday, with apparently no news to justify the movement.

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image for news What's Going On Sarepta Stock On Wednesday?
Sarepta Therapeutics to Present New Data from its Neuromuscular Portfolio at 2025 World Muscle Society Congress
SRPT
Published: October 03, 2025 by: Business Wire
Sentiment: Neutral

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Sarepta Therapeutics, Inc. (NASDAQ:SRPT), the leader in precision genetic medicine for rare diseases, will present at the 30th Annual Congress of the World Muscle Society (WMS) 2025 Congress, taking place Oct. 7-11, 2025, in Vienna, Austria. Sarepta presentations will include results from several studies in the delandistrogene moxeparvovec clinical development program, as well as a real-world evidence study of pulmonary function in advanced-stage patients with.

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image for news Sarepta Therapeutics to Present New Data from its Neuromuscular Portfolio at 2025 World Muscle Society Congress
Kuehn Law Encourages Investors of Sarepta Therapeutics, Inc. to Contact Law Firm
SRPT
Published: September 24, 2025 by: PRNewsWire
Sentiment: Neutral

NEW YORK , Sept. 24, 2025 /PRNewswire/ -- Kuehn Law, PLLC, a shareholder litigation law firm, is investigating whether certain officers and directors of Sarepta Therapeutics, Inc. (NASDAQ: SRPT) breached their fiduciary duties to shareholders.

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image for news Kuehn Law Encourages Investors of Sarepta Therapeutics, Inc. to Contact Law Firm
Sarepta Therapeutics Announces Recipients of Route 79, The Duchenne Scholarship Program, for the 2025-2026 Academic Year
SRPT
Published: September 05, 2025 by: Business Wire
Sentiment: Neutral

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Sarepta Therapeutics, Inc. (NASDAQ:SRPT), the leader in precision genetic medicine for rare diseases, today announced 25 recipients of Route 79, The Duchenne Scholarship Program, for the 2025-2026 academic year. Of the academic scholarships, 20 will be awarded to individuals living with Duchenne and five to siblings of individuals living with Duchenne. Now in its eighth year, the program was created to recognize individuals living with Duchenne muscular dystro.

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image for news Sarepta Therapeutics Announces Recipients of Route 79, The Duchenne Scholarship Program, for the 2025-2026 Academic Year
SRPT Stock Alert: Investors with Large Losses Should Contact Robbins LLP for Information About the Pending Lead Plaintiff Deadline in the Sarepta Therapeutics, Inc. Class Action
SRPT
Published: August 29, 2025 by: GlobeNewsWire
Sentiment: Neutral

SAN DIEGO, Aug. 29, 2025 (GLOBE NEWSWIRE) -- Robbins LLP reminds stockholders that a class action was filed on behalf of investors who purchased or otherwise acquired Sarepta Therapeutics, Inc. (NASDAQ: SRPT) securities between June 22, 2023 and June 24, 2025. Sarepta is a commercial-stage biopharmaceutical company that focuses on RNA and gene therapies for the treatment of rare diseases.

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image for news SRPT Stock Alert: Investors with Large Losses Should Contact Robbins LLP for Information About the Pending Lead Plaintiff Deadline in the Sarepta Therapeutics, Inc. Class Action
SAREPTA FINAL DEADLINE ALERT: Bragar Eagel & Squire, P.C. Reminds Investors that a Class Action Lawsuit Has Been Filed Against Sarepta Therapeutics, Inc. and Encourages Investors to Contact the Firm Before the August 25th Deadline
SRPT
Published: August 25, 2025 by: GlobeNewsWire
Sentiment: Neutral

Bragar Eagel & Squire, P.C. Litigation Partner Brandon Walker Encourages Investors Who Suffered Losses In Sarepta (SRPT) To Contact Him Directly To Discuss Their Options

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image for news SAREPTA FINAL DEADLINE ALERT: Bragar Eagel & Squire, P.C. Reminds Investors that a Class Action Lawsuit Has Been Filed Against Sarepta Therapeutics, Inc. and Encourages Investors to Contact the Firm Before the August 25th Deadline
FINAL DEADLINE ALERT: Faruqi & Faruqi, LLP Investigates Claims on Behalf of Investors of Sarepta Therapeutics
SRPT
Published: August 25, 2025 by: Business Wire
Sentiment: Neutral

NEW YORK--(BUSINESS WIRE)---- $SRPT #ClassAction--Faruqi & Faruqi, LLP, a leading national securities law firm, is investigating potential claims against Sarepta Therapeutics, Inc. (“Sarepta” or the “Company”) (NASDAQ: SRPT) and reminds investors of the August 25, 2025 deadline to seek the role of lead plaintiff in a federal securities class action that has been filed against the Company. Faruqi & Faruqi is a leading national securities law firm with offices in New York, Pennsylvania, California and Georgia.

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image for news FINAL DEADLINE ALERT: Faruqi & Faruqi, LLP Investigates Claims on Behalf of Investors of Sarepta Therapeutics
INVESTOR ALERT: Pomerantz Law Firm Reminds Investors with Losses on their Investment in Sarepta Therapeutics, Inc. of Class Action Lawsuit and Upcoming Deadlines - SRPT
SRPT
Published: August 25, 2025 by: GlobeNewsWire
Sentiment: Neutral

NEW YORK, Aug. 25, 2025 (GLOBE NEWSWIRE) -- Pomerantz LLP announces that a class action lawsuit has been filed against Sarepta Therapeutics, Inc. (“Sarepta” or the “Company”) (NASDAQ: SRPT). Such investors are advised to contact Danielle Peyton at [email protected] or 646-581-9980, (or 888.4-POMLAW), toll-free, Ext. 7980. Those who inquire by e-mail are encouraged to include their mailing address, telephone number, and the number of shares purchased.

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image for news INVESTOR ALERT: Pomerantz Law Firm Reminds Investors with Losses on their Investment in Sarepta Therapeutics, Inc. of Class Action Lawsuit and Upcoming Deadlines - SRPT
SRPT Deadline: SRPT Investors with Losses in Excess of $100K Have Opportunity to Lead Sarepta Therapeutics, Inc. Securities Fraud Lawsuit
SRPT
Published: August 22, 2025 by: PRNewsWire
Sentiment: Neutral

NEW YORK , Aug. 22, 2025 /PRNewswire/ -- Why: Rosen Law Firm, a global investor rights law firm, reminds purchasers of securities of Sarepta Therapeutics, Inc. (NASDAQ: SRPT) between June 22, 2023 and June 24, 2025, both dates inclusive (the "Class Period"), of the important August 25, 2025 lead plaintiff deadline. So What: If you purchased Sarepta Therapeutics securities during the Class Period you may be entitled to compensation without payment of any out of pocket fees or costs through a contingency fee arrangement.

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image for news SRPT Deadline: SRPT Investors with Losses in Excess of $100K Have Opportunity to Lead Sarepta Therapeutics, Inc. Securities Fraud Lawsuit
INVESTOR DEADLINE MONDAY: Sarepta Therapeutics, Inc. Investors with Substantial Losses Have Opportunity to Lead Class Action Lawsuit - SRPT
SRPT
Published: August 22, 2025 by: PRNewsWire
Sentiment: Neutral

SAN DIEGO , Aug. 22, 2025 /PRNewswire/ -- Robbins Geller Rudman & Dowd LLP announces that purchasers or acquirers of Sarepta Therapeutics, Inc. (NASDAQ: SRPT) securities between June 22, 2023 and June 24, 2025, inclusive (the "Class Period"), have until this Monday, August 25, 2025 to seek appointment as lead plaintiff of the Sarepta class action lawsuit. Captioned Dolgicer v.

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image for news INVESTOR DEADLINE MONDAY: Sarepta Therapeutics, Inc. Investors with Substantial Losses Have Opportunity to Lead Class Action Lawsuit - SRPT
Sarepta Therapeutics: A Strong Opportunity Amidst The Panic
SRPT
Published: August 22, 2025 by: Seeking Alpha
Sentiment: Positive

Sarepta Therapeutics is trading at a huge discount to previous enterprise value, with significant upside potential as the situation stabilizes in the near term. ELEVIDYS may be able to regain the non-ambulatory segment in the future, leading to further opportunity. Company restructuring sets up a realistic shot of turnaround.

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image for news Sarepta Therapeutics: A Strong Opportunity Amidst The Panic

About Sarepta Therapeutics, Inc. (SRPT)

  • IPO Date 1997-06-04
  • Website https://www.sarepta.com
  • Industry Biotechnology
  • CEO Douglas S. Ingram
  • Employees 1372

Sarepta Therapeutics, Inc., a commercial-stage biopharmaceutical company, focuses on the discovery and development of RNA-targeted therapeutics, gene therapies, and other genetic therapeutic modalities for the treatment of rare diseases. It offers EXONDYS 51 injection to treat duchenne muscular dystrophy (duchenne) in patients with confirmed mutation of the dystrophin gene that is amenable to exon 51 skipping; and VYONDYS 53 for the treatment of duchenne in patients with confirmed mutation of the dystrophin gene that is amenable to exon 53 skipping. The company is also developing AMONDYS 45, a product candidate that uses phosphorodiamidate morpholino oligomer chemistry and exon-skipping technology to skip exon 45 of the dystrophin gene; SRP-5051, a peptide conjugated PMO that binds exon 51 of dystrophin pre-mRNA; SRP-9001, a DMD micro-dystrophin gene therapy program; and SRP-9003, a limb-girdle muscular dystrophies gene therapy program. It has collaboration agreements with F. Hoffman-La Roche Ltd; Nationwide Children's Hospital; Lysogene; Duke University; Genethon; and StrideBio. The company was incorporated in 1980 and is headquartered in Cambridge, Massachusetts.