XXII

Initial 60-Store California Entry Extends XXII's Reduced-Nicotine Rollout Into One of the Nation's Largest and Most Influential Tobacco Markets, With a Pathway to Broader Expansion  MOCKSVILLE, N.C., May 21, 2026 (GLOBE NEWSWIRE) -- 22nd Century Group, Inc. (Nasdaq: XXII), a tobacco products company focused on reducing the harms of smoking through nicotine reduction, today announced the expansion of Pinnacle VLN® into the state of California through an initial approximately 60-store retail trial, establishing the brand's first retail presence in the state and opening another strategically important market for the Company's FDA-authorized reduced-nicotine cigarette platform.

New Product Introduction Broadens XXII's Fast-Scaling Pinnacle Brand Reinforcing Brand Power, Opening New Retail Doors, and Strengthening the Company's Revenue and Margin Expansion Story  MOCKSVILLE, N.C., May 18, 2026 (GLOBE NEWSWIRE) -- 22nd Century Group, Inc. (Nasdaq: XXII), a tobacco products company focused on reducing the harms of smoking through nicotine reduction, today announced the launch of Pinnacle Pure, a new tobacco and water style combustible cigarette, further expanding the Company's growing family of Pinnacle branded products, expected to be sold through multiple top national retailers in the United States and over 2,000 locations.

VLN® Product Launch in Over 150 New High-Visibility Store Locations Positions XXII to Introduce VLN® to New Consumers and Potentially Capture a Large Adult-Smoker Market, Accelerate High-Margin Revenue

FDA filing covers renewal applications for VLN® King and VLN® Menthol King, the first combusted cigarettes authorized as Modified Risk Tobacco Products, as 22nd Century advances its regulatory pathway for continued modified risk marketing status

Continues VLN ® Commercial Expansion with New Stores Selling Proprietary Branded VLN ® Products

MOCKSVILLE, N.C., May 04, 2026 (GLOBE NEWSWIRE) -- 22nd Century Group, Inc. (Nasdaq: XXII), the only tobacco products company that has for 28 years led and continues to lead the fight against the harms of smoking driven by nicotine addiction,, will host a webcast on Thursday, May 7, 2026, at 8:00 AM ET to discuss its 2026 first quarter results, which are to be reported in a press release at 6:00 AM ET the same day.

Chairman & CEO Larry Firestone Details 2026 Priorities and Shareholder Value Strategy MOCKSVILLE, N.C., April 29, 2026 (GLOBE NEWSWIRE) -- 22nd Century Group, Inc. (Nasdaq: XXII), the only tobacco products company that has for 28 years led and continues to lead the fight against the harms of smoking driven by nicotine addiction, today issued the following letter to stockholders from Lawrence Firestone, the Chairman and Chief Executive Officer of 22nd Century Group, Inc.:  Dear Fellow Stockholders, As I reflect on the past year, I am proud of the progress our team has made to form the foundation of the future 22nd Century Group and position the company for long-term growth and success.

MOCKSVILLE, N.C., April 23, 2026 (GLOBE NEWSWIRE) -- 22nd Century Group, Inc. (Nasdaq: XXII), a tobacco products company focused on nicotine reduction and plant biotechnology, today announced corporate updates regarding a new testing services agreement with North Carolina State University aimed at validating tobacco varieties featuring improved leaf quality and increased crop yields with the same low-nicotine content.

Company to Pursue Additional PMTA Submissions, Building on Its Status as the Only Holder of an FDA-Authorized Low Nicotine Combustible Cigarette Branded as VLN ® Products Expanded PMTA Portfolio and Licensing Strategy Designed to Address Wider Consumer Preference and Unlock Further Retail Penetration Opportunities MOCKSVILLE, N.C., April 07, 2026 (GLOBE NEWSWIRE) -- 22nd Century Group, Inc. (Nasdaq: XXII), a tobacco products company focused on reducing the harms of smoking through nicotine reduction, today announced an update on the advancement of a 100mm VLN® reduced nicotine content cigarette.

22nd Century Group, Inc. (XXII) Q4 2025 Earnings Call Prepared Remarks Transcript