SOMERSET, N.J., June 03, 2025 (GLOBE NEWSWIRE) -- Legend Biotech Corporation (NASDAQ: LEGN) (Legend Biotech), a global leader in cell therapy, announced today new long-term results from the CARTITUDE-1 study in heavily pretreated relapsed/refractory multiple myeloma (RRMM) patients. RRMM patients were treated with a single infusion of CARVYKTI® (ciltacabtagene autoleucel; cilta-cel) with no maintenance or subsequent myeloma therapy. Notably, an unprecedented 33% (32 of 97) of patients remained progression-free for five years or more.

image for news Legend Biotech Unveils Groundbreaking 5-Year Survival Data for CARVYKTI® in Multiple Myeloma at 2025 ASCO Annual Meeting

ROCHESTER, N.Y. , June 3, 2025 /PRNewswire/ -- Vuzix® Corporation (NASDAQ: VUZI), ("Vuzix" or, the "Company"), a leading supplier of AI-powered smart glasses, waveguides and Augmented Reality (AR) technologies, today announced that the Company and Wyr.ai Private Limited ("Wyr.ai"), a trailblazing XR and AI product company that revolutionizes industries through cutting-edge technology, have partnered to launch a new AI-driven quality assurance inspection platform that uses Vuzix M400™ smart glasses.

image for news Wyr.ai Partners with Vuzix to Launch Its New M400 Smart Glasses-based AI-driven Quality Assurance Inspection Platform

Results from the Phase 3 AMPLITUDE study show the potential of niraparib and abiraterone acetate to delay cancer progression and worsening of symptoms1

image for news Johnson & Johnson's AKEEGA® (niraparib and abiraterone acetate dual-action tablet) is the first PARP inhibitor combo to show improved efficacy in patients with HRR-mutated mHSPC vs. current standard of care

New long-term CARTITUDE-1 data show one-third of patients treated with CARVYKTI ® remain progression-free CARTITUDE-4 analysis shows compelling overall survival and progression-free benefits in standard and high-risk subgroups across prior lines of treatment CHICAGO , June 3, 2025 /PRNewswire/ -- Johnson & Johnson (NYSE:JNJ) announced today new long-term follow-up data from the Phase 1b/2 CARTITUDE-1 study demonstrating 33 percent (n=32) of patients in the study (n=97) with relapsed or refractory multiple myeloma (RRMM) treated with CARVYKTI® (ciltacabtagene autoleucel; cilta-cel) achieved progression-free survival (PFS) of five years or more with a single infusion and no maintenance or subsequent anti-myeloma therapy.1 These …

image for news Single infusion of CARVYKTI® (ciltacabtagene autoleucel) delivered lasting treatment-free remissions for at least five years in patients with relapsed or refractory multiple myeloma

Phase 1 trial demonstrates encouraging clinical activity of investigational immunotherapy for relapsed or refractory multiple myeloma Novel investigational dual-antigen-targeting immunotherapy binds to B-cell maturation antigen (BCMA) and GPRC5D on myeloma cells, as well as CD3 on T-cells CHICAGO , June 3, 2025 /PRNewswire/ -- Johnson & Johnson announced today initial Phase 1 results of JNJ-79635322 (JNJ-5322), a novel investigational trispecific antibody (TsAb) in patients with relapsed or refractory multiple myeloma. Among the 36 patients who received the recommended phase 2 dose (RP2D), the overall response rate (ORR) was 86.1 percent.

image for news Early results from Johnson & Johnson's trispecific antibody show promising response in heavily pretreated multiple myeloma patients

More than half of patients maintained minimal residual disease (MRD) negativity (10-5) with DARZALEX FASPRO ® for 24 months or longer in the Phase 3 PERSEUS study Data from Phase 3 CEPHEUS study show 60 percent overall MRD negativity (10−5) and improved PFS with DARZALEX FASPRO ® in transplant-ineligible newly diagnosed patients CHICAGO , June 3, 2025 /PRNewswire/ -- Johnson & Johnson (NYSE: JNJ) today announced data from two studies highlighting that a DARZALEX FASPRO® (daratumumab and hyaluronidase-fihj)-based quadruplet regimen demonstrated deep and sustained minimal residual disease (MRD) negativity rates, and improved long-term progression-free survival (PFS) in patients with newly …

image for news DARZALEX FASPRO® (daratumumab and hyaluronidase-fihj)-based regimen shows 95 percent progression-free survival at four years in transplant-eligible, newly diagnosed patients with multiple myeloma who achieved sustained MRD negativity

Science Applications Stock Plunges 13% as Q1 Earnings Miss Estimates — Negative

SAIC   Zacks Investment Research — June 03, 2025

SAIC stock declines 13% after Q1 earnings miss, flat profits and margin pressure weigh despite modest revenue growth.

image for news Science Applications Stock Plunges 13% as Q1 Earnings Miss Estimates

Hilton Fuels Luxury Growth With New Brands and 500 Hotels Pipeline — Neutral

HLT   Zacks Investment Research — June 03, 2025

HLT hits 1,000 luxury hotels, adds new brands and global partnerships, with 500 more in its upscale pipeline.

image for news Hilton Fuels Luxury Growth With New Brands and 500 Hotels Pipeline

SHANGHAI, and NEW YORK, June 03, 2025 (GLOBE NEWSWIRE) -- TH International Limited (“Tims China” (Nasdaq: THCH)), the exclusive operator of Tim Hortons coffee shops in China, plans to release its first quarter results before market opening on Tuesday June 24, 2025, with a conference call to follow at 8:00 AM EST or 8:00 PM China Standard Time. The conference call will be webcast, and can be accessed on the company website at https://ir.timschina.com/events-presentations/presentations-webcasts.

image for news Tims China Registration & Webcast details for Q1 2025 Results Conference Call on June 24, 2025

Issues Letter to TURN Shareholders Detailing Continued Governance Failures and Mismanagement by 180 Board and Management Team CHICAGO , June 3, 2025 /PRNewswire/ -- Marlton Partners L.P. (together with its affiliates and group members, "Marlton" or "we"), beneficial owners of approximately 5.2% of the outstanding stock of 180 Degree Capital Corp. (NASDAQ: TURN) (the "Company"), today issued an open letter calling on the TURN Board of Directors to immediately set a record date and allow shareholders to vote on the Company's proposed sale to Mount Logan Capital Inc. (Cboe Canada: MLC) ("Mount Logan"): Dear Fellow Shareholders of 180 Degree Capital …

image for news Marlton Partners Calls on 180 Degree Capital Corp. to Set Record Date Now and Allow Shareholders to Determine Company's Future

NEW YORK, NY / ACCESS Newswire / June 3, 2025 / If you suffered a loss on your Viatris Inc. (NASDAQ:VTRS) investment and want to learn about a potential recovery under the federal securities laws, follow the link below for more information: https://zlk.com/pslra-1/viatris-inc-lawsuit-submission-form-2?prid=151460&wire=1&utm_campaign=8 or contact Joseph E. Levi, Esq.

image for news Class Action Lawsuit Filed: Viatris Inc. (VTRS) - Join by June 3, 2025 - Contact Levi & Korsinsky

Meta inks nuclear deal with Constellation Energy under 20-year agreement — Positive

CEG  META   CNBC Television — June 03, 2025

CNBC's Pippa Stevens reports on news regarding Meta.

image for news Meta inks nuclear deal with Constellation Energy under 20-year agreement

Get ready to slay summer. NEW YORK , June 3, 2025 /PRNewswire/ -- Captain Morgan is joining forces with the ultimate queen of chaos, M3GAN, for a summer collab that's serving spice, sass, and serious main character energy.

image for news Hold Onto Your Cocktail: Captain Morgan and Universal Pictures' M3GAN 2.0 Join Forces with a Glow-in-the-Dark Spiced Rum Bottle and Limited-Edition Cocktail Experience

Should You Invest in Nice (NICE) Based on Bullish Wall Street Views? — Positive

NICE   Zacks Investment Research — June 03, 2025

Investors often turn to recommendations made by Wall Street analysts before making a Buy, Sell, or Hold decision about a stock. While media reports about rating changes by these brokerage-firm employed (or sell-side) analysts often affect a stock's price, do they really matter?

image for news Should You Invest in Nice (NICE) Based on Bullish Wall Street Views?

Wall Street Analysts Think Microsoft (MSFT) Is a Good Investment: Is It? — Neutral

MSFT   Zacks Investment Research — June 03, 2025

The recommendations of Wall Street analysts are often relied on by investors when deciding whether to buy, sell, or hold a stock. Media reports about these brokerage-firm-employed (or sell-side) analysts changing their ratings often affect a stock's price.

image for news Wall Street Analysts Think Microsoft (MSFT) Is a Good Investment: Is It?

Is It Worth Investing in Booking Holdings (BKNG) Based on Wall Street's Bullish Views? — Positive

BKNG   Zacks Investment Research — June 03, 2025

When deciding whether to buy, sell, or hold a stock, investors often rely on analyst recommendations. Media reports about rating changes by these brokerage-firm-employed (or sell-side) analysts often influence a stock's price, but are they really important?

image for news Is It Worth Investing in Booking Holdings (BKNG) Based on Wall Street's Bullish Views?

Wall Street Bulls Look Optimistic About Zscaler (ZS): Should You Buy? — Positive

ZS   Zacks Investment Research — June 03, 2025

Investors often turn to recommendations made by Wall Street analysts before making a Buy, Sell, or Hold decision about a stock. While media reports about rating changes by these brokerage-firm employed (or sell-side) analysts often affect a stock's price, do they really matter?

image for news Wall Street Bulls Look Optimistic About Zscaler (ZS): Should You Buy?

Is Archrock Inc. (AROC) a Buy as Wall Street Analysts Look Optimistic? — Positive

AROC   Zacks Investment Research — June 03, 2025

When deciding whether to buy, sell, or hold a stock, investors often rely on analyst recommendations. Media reports about rating changes by these brokerage-firm-employed (or sell-side) analysts often influence a stock's price, but are they really important?

image for news Is Archrock Inc. (AROC) a Buy as Wall Street Analysts Look Optimistic?

The recommendations of Wall Street analysts are often relied on by investors when deciding whether to buy, sell, or hold a stock. Media reports about these brokerage-firm-employed (or sell-side) analysts changing their ratings often affect a stock's price.

image for news Brokers Suggest Investing in Diversified Energy Company PLC (DEC): Read This Before Placing a Bet

Brokers Suggest Investing in Progressive (PGR): Read This Before Placing a Bet — Negative

PGR   Zacks Investment Research — June 03, 2025

The recommendations of Wall Street analysts are often relied on by investors when deciding whether to buy, sell, or hold a stock. Media reports about these brokerage-firm-employed (or sell-side) analysts changing their ratings often affect a stock's price.

image for news Brokers Suggest Investing in Progressive (PGR): Read This Before Placing a Bet