Vertex Pharmaceuticals Incorporated (VRTX)

US — Healthcare Sector
Peers: REGN  CRSP  NVO  SRPT  NTLA  BIIB  INCY  BMRN  ILMN 

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Key Metrics & Ratings

  • symbol VRTX
  • Rev/Share 43.2063
  • Book/Share 64.2129
  • PB 7.1149
  • Debt/Equity 0.1
  • CurrentRatio 2.6456
  • ROIC -0.128

 

  • MktCap 117322845390.0
  • FreeCF/Share -4.8968
  • PFCF -93.2614
  • PE -118.6873
  • Debt/Assets 0.0721
  • DivYield 0
  • ROE -0.0625

 

  • Rating C
  • Score 2
  • Recommendation Sell
  • P/E Score 1
  • DCF Score 4
  • P/B Score 1
  • D/E Score 3

Recent Analyst Ratings

Type Ticker Analyst Firm Previous Rating Current Rating Previous Price Target Current Price Target Date
Downgrade VRTX Wolfe Research Outperform Peer Perform -- -- May 7, 2025
Downgrade VRTX Leerink Partners Outperform Market Perform -- $503 May 6, 2025
Resumed VRTX Cantor Fitzgerald -- Overweight -- $535 April 22, 2025
Upgrade VRTX Canaccord Genuity Sell Hold $408 $424 Feb. 12, 2025
Upgrade VRTX Canaccord Genuity Sell Hold -- -- Feb. 11, 2025
Downgrade VRTX Wells Fargo Overweight Equal Weight -- $460 Jan. 30, 2025
Reiterated VRTX H.C. Wainwright -- Buy $600 $535 Dec. 20, 2024
Downgrade VRTX Oppenheimer Outperform Perform -- -- Dec. 19, 2024
Upgrade VRTX Jefferies Hold Buy $500 $550 Dec. 9, 2024
Initiation VRTX Scotiabank -- Sector Perform -- -- Oct. 16, 2024

News

Why Vertex Pharmaceuticals Stock Is Sinking Today
VRTX
Published: May 06, 2025 by: The Motley Fool
Sentiment: Negative

Shares of Vertex Pharmaceuticals (VRTX -11.69%) were sinking 11.9% as of 10:18 a.m. ET on Tuesday.

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image for news Why Vertex Pharmaceuticals Stock Is Sinking Today
Rising Costs Weigh on Vertex Q1 Earnings
VRTX
Published: May 06, 2025 by: The Motley Fool
Sentiment: Neutral

Here's our initial take on Vertex Pharmaceuticals' (VRTX -0.27%) first-quarter financial report.

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image for news Rising Costs Weigh on Vertex Q1 Earnings
Vertex: Improved Outlook Despite First Quarter Miss (Rating Upgrade)
VRTX
Published: May 06, 2025 by: Seeking Alpha
Sentiment: Positive

Vertex Pharmaceuticals missed Q1 revenue and EPS estimates but this is not a cause for concern as the full-year outlook has improved. Alyftrek is off to a good start and early launch metrics of Journavx look promising. Casgevy's progress is slow but uptake should improve going forward.

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image for news Vertex: Improved Outlook Despite First Quarter Miss (Rating Upgrade)
Final Trades: Berkshire Hathaway, Vertex Pharma, S&P Global and CME Group
BRK-A, BRK-B, CME, VRTX
Published: April 30, 2025 by: CNBC Television
Sentiment: Neutral

Final Trades are in! The Investment Committee reveals their top picks to close out the day—don't miss it!

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image for news Final Trades: Berkshire Hathaway, Vertex Pharma, S&P Global and CME Group
What Analyst Projections for Key Metrics Reveal About Vertex (VRTX) Q1 Earnings
VRTX
Published: April 30, 2025 by: Zacks Investment Research
Sentiment: Positive

Looking beyond Wall Street's top -and-bottom-line estimate forecasts for Vertex (VRTX), delve into some of its key metrics to gain a deeper insight into the company's potential performance for the quarter ended March 2025.

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image for news What Analyst Projections for Key Metrics Reveal About Vertex (VRTX) Q1 Earnings
Baron Health Care Fund Q1 2025 Top Contributors And Detractors
ACLX, BSX, DHR, GKOS, INSM, ISRG, LLY, RDNT, UNH, VRTX
Published: April 29, 2025 by: Seeking Alpha
Sentiment: Positive

Boston Scientific's shares rose due to strong market growth, innovative products like pulsed field ablation, and disciplined cost management, driving double-digit EPS growth. Vertex Pharmaceuticals saw increased investor confidence in its cystic fibrosis franchise and evolving pipeline, including promising non-opioid pain treatments and kidney disease drugs. UnitedHealth Group's shares gained as 2024 headwinds subsided, Medicare Advantage rates improved, and higher-margin Optum segments grew, insulating it from tariff impacts.

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image for news Baron Health Care Fund Q1 2025 Top Contributors And Detractors
My 5 Top Stocks to Buy Right Now in This Highly Volatile Market
BRK-A, BRK-B, D, EPD, PFE, VRTX
Published: April 28, 2025 by: The Motley Fool
Sentiment: Positive

Getting dizzy from the stock market's gyrations? Join the club.

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image for news My 5 Top Stocks to Buy Right Now in This Highly Volatile Market
Vertex Pharmaceuticals Incorporated (VRTX) Is a Trending Stock: Facts to Know Before Betting on It
VRTX
Published: April 23, 2025 by: Zacks Investment Research
Sentiment: Positive

Vertex (VRTX) has been one of the stocks most watched by Zacks.com users lately. So, it is worth exploring what lies ahead for the stock.

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image for news Vertex Pharmaceuticals Incorporated (VRTX) Is a Trending Stock: Facts to Know Before Betting on It
Why Investors Need to Take Advantage of These 2 Medical Stocks Now
CAH, VRTX
Published: April 22, 2025 by: Zacks Investment Research
Sentiment: Positive

The Zacks Earnings ESP is a great way to find potential earnings surprises. Why investors should take advantage now.

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image for news Why Investors Need to Take Advantage of These 2 Medical Stocks Now
3 Relatively Safe Healthcare Growth Stocks You Can Buy and Hold
AMGN, LLY, VRTX
Published: April 22, 2025 by: The Motley Fool
Sentiment: Positive

When the stock market is highly volatile, many investors flock to assets that offer stability but dismal growth prospects. However, you don't necessarily have to sacrifice growth for safety.

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image for news 3 Relatively Safe Healthcare Growth Stocks You Can Buy and Hold
Fed Chairman Jerome Powell Warns Trump's Tariffs Could Cause Stagflation: 3 Stocks to Buy and Hold if He's Right
D, KR, VRTX
Published: April 22, 2025 by: The Motley Fool
Sentiment: Negative

President Trump isn't a fan of Fed Chairman Jerome Powell, despite nominating Powell to replace Janet Yellen in 2017. Trump recently called Powell a "major loser" on a social media post and demanded that he lower interest rates immediately.

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image for news Fed Chairman Jerome Powell Warns Trump's Tariffs Could Cause Stagflation: 3 Stocks to Buy and Hold if He's Right
Final Trades: Vertex, Robinhood, Palo Alto and Crowdstrike
CRWD, HOOD, PANW, VRTX
Published: April 10, 2025 by: CNBC Television
Sentiment: Neutral

The Investment Committee give you their top stocks to watch in this volatile markets.

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image for news Final Trades: Vertex, Robinhood, Palo Alto and Crowdstrike
Investors Heavily Search Vertex Pharmaceuticals Incorporated (VRTX): Here is What You Need to Know
VRTX
Published: April 09, 2025 by: Zacks Investment Research
Sentiment: Positive

Recently, Zacks.com users have been paying close attention to Vertex (VRTX). This makes it worthwhile to examine what the stock has in store.

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image for news Investors Heavily Search Vertex Pharmaceuticals Incorporated (VRTX): Here is What You Need to Know
Corporate CFOs Think a Recession Is Coming. Here Are 3 Stocks to Own If They're Right.
D, VRTX, WMT
Published: April 04, 2025 by: The Motley Fool
Sentiment: Neutral

Which group of individuals is in the best position to spot early warning signs of economic trouble? There's a good case to be made for corporate chief financial officers (CFOs).

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image for news Corporate CFOs Think a Recession Is Coming. Here Are 3 Stocks to Own If They're Right.
Vertex Pharmaceuticals (VRTX) Increases Despite Market Slip: Here's What You Need to Know
VRTX
Published: April 03, 2025 by: Zacks Investment Research
Sentiment: Negative

Vertex Pharmaceuticals (VRTX) reachead $484.01 at the closing of the latest trading day, reflecting a +0.11% change compared to its last close.

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image for news Vertex Pharmaceuticals (VRTX) Increases Despite Market Slip: Here's What You Need to Know
Trump's tariffs are a new challenge for Big Pharma. Here are the best positioned stocks
ABBV, AMGN, BMY, GILD, LLY, MRK, MRNA, PFE, VRTX
Published: April 01, 2025 by: CNBC
Sentiment: Negative

Leerink Partners analyst David Resinger warned his clients on Sunday that the tariff risks to the industry are 'underappreciated.'

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image for news Trump's tariffs are a new challenge for Big Pharma. Here are the best positioned stocks
VRTX Provides Mixed Updates for Type 1 Diabetes Pipeline Candidates
VRTX
Published: April 01, 2025 by: Zacks Investment Research
Sentiment: Positive

Vertex plans to submit regulatory filings seeking approval for zimislecel in type 1 diabetes in 2026. However, it is likely to stop further development of VX-264.

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image for news VRTX Provides Mixed Updates for Type 1 Diabetes Pipeline Candidates
Biopharma firms with foreign exposure face disruption as Trump's tariffs loom
AMGN, BIIB, GILD, VRTX
Published: March 27, 2025 by: Proactive Investors
Sentiment: Negative

The biopharmaceutical industry is bracing for potential disruptions from proposed tariffs aimed at encouraging companies to move manufacturing operations back to the United States. This week, president Donald Trump suggested that tariffs could be implemented on pharma products made outside the US, with a particular focus on Ireland, where many biopharma companies benefit from favorable tax conditions.

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image for news Biopharma firms with foreign exposure face disruption as Trump's tariffs loom
Trade Tracker: Steve Weiss buys Vertex Pharmaceuticals
VRTX
Published: March 24, 2025 by: CNBC Television
Sentiment: Positive

Steve Weiss, Founder and Managing Partner of Short Hills Capital Partners joins CNBC's “Halftime Report” to explain why he's buying the Pharmaceutical company

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image for news Trade Tracker: Steve Weiss buys Vertex Pharmaceuticals
Vertex Up 25% YTD: Should You Buy, Sell or Hold the Stock?
VRTX
Published: March 17, 2025 by: Zacks Investment Research
Sentiment: Positive

Those who already own VRTX stock may retain it for some time to see if its CF sales continue to rise and how the Journavx and Alyftrek launch progress.

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image for news Vertex Up 25% YTD: Should You Buy, Sell or Hold the Stock?
Final Trades: Netflix, Meta, Vertex, Interactive Brokers and the COWZ
IBKR, META, NFLX, COWZ, VRTX
Published: March 11, 2025 by: CNBC Television
Sentiment: Neutral

The Investment Committee give you their top stocks to watch for the second half.

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image for news Final Trades: Netflix, Meta, Vertex, Interactive Brokers and the COWZ
Vertex Pharmaceuticals Incorporated (VRTX) Leerink's Global Healthcare Conference 2025 (Transcript)
VRTX
Published: March 10, 2025 by: Seeking Alpha
Sentiment: Neutral

Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX ) Leerink's Global Healthcare Conference 2025 March 10, 2025 10:00 AM ET Company Participants Charlie Wagner - CFO and COO David Altshuler - Chief Scientific Officer Conference Call Participants Dave Risinger - Leerink Partners Dave Risinger Great. Well thanks very much, everyone, for joining us for our next session with Vertex.

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image for news Vertex Pharmaceuticals Incorporated (VRTX) Leerink's Global Healthcare Conference 2025 (Transcript)
Vertex Pharmaceuticals: Company Passes My Health Check With Flying Colors, Upholding Buy Rating
VRTX
Published: March 06, 2025 by: Seeking Alpha
Sentiment: Positive

Vertex Pharmaceuticals Incorporated's stock has shown resilience, recovering from dips and maintaining a strong long-term growth trajectory, driven by its robust CF franchise and new product approvals. The company's 2024 performance was solid, with TRIKAFTA/KAFTRIO generating >$10bn revenues, and 2025 guidance suggesting continued growth despite some challenges. Vertex's diversification efforts include the approval of pain therapy JOURNAVX and gene therapy Casgevy, with potential multi-billion-dollar revenue contributions from these and other pipeline drugs.

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image for news Vertex Pharmaceuticals: Company Passes My Health Check With Flying Colors, Upholding Buy Rating
Vertex Pharmaceuticals Incorporated (VRTX) is Attracting Investor Attention: Here is What You Should Know
VRTX
Published: February 25, 2025 by: Zacks Investment Research
Sentiment: Positive

Vertex (VRTX) has been one of the stocks most watched by Zacks.com users lately. So, it is worth exploring what lies ahead for the stock.

Read More
image for news Vertex Pharmaceuticals Incorporated (VRTX) is Attracting Investor Attention: Here is What You Should Know
2 No-Brainer Healthcare Stocks to Buy With $500 Right Now
PFE, VRTX
Published: February 21, 2025 by: The Motley Fool
Sentiment: Positive

Looking for a good area in which to invest? Consider the healthcare sector.

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image for news 2 No-Brainer Healthcare Stocks to Buy With $500 Right Now
GILD or VRTX: Which Is the Better Value Stock Right Now?
GILD, VRTX
Published: February 20, 2025 by: Zacks Investment Research
Sentiment: Positive

Investors interested in stocks from the Medical - Biomedical and Genetics sector have probably already heard of Gilead Sciences (GILD) and Vertex Pharmaceuticals (VRTX). But which of these two companies is the best option for those looking for undervalued stocks?

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image for news GILD or VRTX: Which Is the Better Value Stock Right Now?
3 Stocks That Could Trounce the Market in 2025
LLY, SMMT, VRTX
Published: February 17, 2025 by: The Motley Fool
Sentiment: Positive

If you're content with market-level returns, investing in an exchange-traded fund (ETF) is the way to go. But if not, you'll need to find stocks that hold the potential to pack more punch.

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image for news 3 Stocks That Could Trounce the Market in 2025
Vertex Pharmaceuticals Incorporated (VRTX) Is a Trending Stock: Facts to Know Before Betting on It
VRTX
Published: February 14, 2025 by: Zacks Investment Research
Sentiment: Positive

Vertex (VRTX) has been one of the stocks most watched by Zacks.com users lately. So, it is worth exploring what lies ahead for the stock.

Read More
image for news Vertex Pharmaceuticals Incorporated (VRTX) Is a Trending Stock: Facts to Know Before Betting on It
Levi & Korsinsky Announces an Investigation on Behalf of Vertex Pharmaceuticals Incorporated (VRTX) Shareholders Who May Have Been Affected by Fraud
VRTX
Published: February 14, 2025 by: Accesswire
Sentiment: Neutral

NEW YORK, NY / ACCESS Newswire / February 14, 2025 / Levi & Korsinsky notifies investors that it has commenced an investigation of Vertex Pharmaceuticals Incorporated ("Vertex Pharmaceuticals") (NASDAQ:VRTX) concerning possible violations of federal securities laws. On December 19, 2024, the company reported disappointing results from its RewinD-LB Phase 2b clinical trial for the pain drug suzetrigine.

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image for news Levi & Korsinsky Announces an Investigation on Behalf of Vertex Pharmaceuticals Incorporated (VRTX) Shareholders Who May Have Been Affected by Fraud
The Ultimate Healthcare Stock to Buy With $500 Right Now
VRTX
Published: February 14, 2025 by: The Motley Fool
Sentiment: Positive

Healthcare isn't the hottest sector these days. While the S&P 500 has soared nearly 21% over the last 12 months, healthcare stocks as a group are barely in positive territory.

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image for news The Ultimate Healthcare Stock to Buy With $500 Right Now

About Vertex Pharmaceuticals Incorporated (VRTX)

  • IPO Date 1991-07-24
  • Website https://www.vrtx.com
  • Industry Biotechnology
  • CEO Reshma Kewalramani FASN,
  • Employees 6100

Vertex Pharmaceuticals Incorporated, a biotechnology company, engages in developing and commercializing therapies for treating cystic fibrosis. The company markets SYMDEKO/SYMKEVI, ORKAMBI, and KALYDECO to treat patients with cystic fibrosis who have specific mutations in their cystic fibrosis transmembrane conductance regulator gene; and TRIKAFTA for the treatment of patients with CF 6 years of age or older who have at least one F508del mutation. Its pipeline includes VX-864 for the treatment of AAT deficiency, which is in Phase 2 clinical trial; VX-147 for the treatment of APOL1-mediated focal segmental glomerulosclerosis, or FSGS, and other serious kidney diseases which is in Phase 2 clinical trial; VX- 880, treatment for Type 1 Diabetes which is in Phase 1/2 clinical trial; VX-548, a NaV1.8 inhibitor for treatments of acute, neuropathic, musculoskeletal pain which is in Phase 2 clinical trial; and CTX001 for the treatment severe SCD and TDT which is in Phase 3 clinical trial. The company sells its products primarily to specialty pharmacy and specialty distributors in the United States, as well as specialty distributors and retail chains, and hospitals and clinics internationally. It has collaborations with Affinia Therapeutics, Inc.; Arbor Biotechnologies, Inc.; CRISPR Therapeutics AG.; Kymera Therapeutics, Inc.; Mammoth Biosciences, Inc.; Moderna, Inc.; Obsidian Therapeutics, Inc.; and Skyhawk Therapeutics, Inc.; as well as Ribometrix, Inc.; Genomics plc; Merck KGaA; Darmstadt, Germany, and X-Chem, Inc. Vertex Pharmaceuticals Incorporated was founded in 1989 and is headquartered in Boston, Massachusetts.