Vertex Pharmaceuticals Incorporated (VRTX)

US — Healthcare Sector
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Key Metrics & Ratings

  • symbol VRTX
  • Rev/Share 43.2063
  • Book/Share 64.2129
  • PB 6.9531
  • Debt/Equity 0.1
  • CurrentRatio 2.6456
  • ROIC -0.128

 

  • MktCap 114654724560.0
  • FreeCF/Share -4.8968
  • PFCF -91.1405
  • PE -115.9882
  • Debt/Assets 0.0721
  • DivYield 0
  • ROE -0.0625

 

  • Rating C
  • Score 2
  • Recommendation Sell
  • P/E Score 1
  • DCF Score 4
  • P/B Score 1
  • D/E Score 3

Recent Analyst Ratings

Type Ticker Analyst Firm Previous Rating Current Rating Previous Price Target Current Price Target Date
Downgrade VRTX Wolfe Research Outperform Peer Perform -- -- May 7, 2025
Downgrade VRTX Leerink Partners Outperform Market Perform -- $503 May 6, 2025
Resumed VRTX Cantor Fitzgerald -- Overweight -- $535 April 22, 2025
Upgrade VRTX Canaccord Genuity Sell Hold $408 $424 Feb. 12, 2025
Upgrade VRTX Canaccord Genuity Sell Hold -- -- Feb. 11, 2025
Downgrade VRTX Wells Fargo Overweight Equal Weight -- $460 Jan. 30, 2025
Reiterated VRTX H.C. Wainwright -- Buy $600 $535 Dec. 20, 2024
Downgrade VRTX Oppenheimer Outperform Perform -- -- Dec. 19, 2024
Upgrade VRTX Jefferies Hold Buy $500 $550 Dec. 9, 2024
Initiation VRTX Scotiabank -- Sector Perform -- -- Oct. 16, 2024

News

Biopharma firms with foreign exposure face disruption as Trump's tariffs loom
AMGN, BIIB, GILD, VRTX
Published: March 27, 2025 by: Proactive Investors
Sentiment: Negative

The biopharmaceutical industry is bracing for potential disruptions from proposed tariffs aimed at encouraging companies to move manufacturing operations back to the United States. This week, president Donald Trump suggested that tariffs could be implemented on pharma products made outside the US, with a particular focus on Ireland, where many biopharma companies benefit from favorable tax conditions.

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image for news Biopharma firms with foreign exposure face disruption as Trump's tariffs loom
Trade Tracker: Steve Weiss buys Vertex Pharmaceuticals
VRTX
Published: March 24, 2025 by: CNBC Television
Sentiment: Positive

Steve Weiss, Founder and Managing Partner of Short Hills Capital Partners joins CNBC's “Halftime Report” to explain why he's buying the Pharmaceutical company

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image for news Trade Tracker: Steve Weiss buys Vertex Pharmaceuticals
Vertex Up 25% YTD: Should You Buy, Sell or Hold the Stock?
VRTX
Published: March 17, 2025 by: Zacks Investment Research
Sentiment: Positive

Those who already own VRTX stock may retain it for some time to see if its CF sales continue to rise and how the Journavx and Alyftrek launch progress.

Read More
image for news Vertex Up 25% YTD: Should You Buy, Sell or Hold the Stock?
Final Trades: Netflix, Meta, Vertex, Interactive Brokers and the COWZ
IBKR, META, NFLX, COWZ, VRTX
Published: March 11, 2025 by: CNBC Television
Sentiment: Neutral

The Investment Committee give you their top stocks to watch for the second half.

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image for news Final Trades: Netflix, Meta, Vertex, Interactive Brokers and the COWZ
Vertex Pharmaceuticals Incorporated (VRTX) Leerink's Global Healthcare Conference 2025 (Transcript)
VRTX
Published: March 10, 2025 by: Seeking Alpha
Sentiment: Neutral

Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX ) Leerink's Global Healthcare Conference 2025 March 10, 2025 10:00 AM ET Company Participants Charlie Wagner - CFO and COO David Altshuler - Chief Scientific Officer Conference Call Participants Dave Risinger - Leerink Partners Dave Risinger Great. Well thanks very much, everyone, for joining us for our next session with Vertex.

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image for news Vertex Pharmaceuticals Incorporated (VRTX) Leerink's Global Healthcare Conference 2025 (Transcript)
Vertex Pharmaceuticals: Company Passes My Health Check With Flying Colors, Upholding Buy Rating
VRTX
Published: March 06, 2025 by: Seeking Alpha
Sentiment: Positive

Vertex Pharmaceuticals Incorporated's stock has shown resilience, recovering from dips and maintaining a strong long-term growth trajectory, driven by its robust CF franchise and new product approvals. The company's 2024 performance was solid, with TRIKAFTA/KAFTRIO generating >$10bn revenues, and 2025 guidance suggesting continued growth despite some challenges. Vertex's diversification efforts include the approval of pain therapy JOURNAVX and gene therapy Casgevy, with potential multi-billion-dollar revenue contributions from these and other pipeline drugs.

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image for news Vertex Pharmaceuticals: Company Passes My Health Check With Flying Colors, Upholding Buy Rating
Vertex Pharmaceuticals Incorporated (VRTX) is Attracting Investor Attention: Here is What You Should Know
VRTX
Published: February 25, 2025 by: Zacks Investment Research
Sentiment: Positive

Vertex (VRTX) has been one of the stocks most watched by Zacks.com users lately. So, it is worth exploring what lies ahead for the stock.

Read More
image for news Vertex Pharmaceuticals Incorporated (VRTX) is Attracting Investor Attention: Here is What You Should Know
2 No-Brainer Healthcare Stocks to Buy With $500 Right Now
PFE, VRTX
Published: February 21, 2025 by: The Motley Fool
Sentiment: Positive

Looking for a good area in which to invest? Consider the healthcare sector.

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image for news 2 No-Brainer Healthcare Stocks to Buy With $500 Right Now
GILD or VRTX: Which Is the Better Value Stock Right Now?
GILD, VRTX
Published: February 20, 2025 by: Zacks Investment Research
Sentiment: Positive

Investors interested in stocks from the Medical - Biomedical and Genetics sector have probably already heard of Gilead Sciences (GILD) and Vertex Pharmaceuticals (VRTX). But which of these two companies is the best option for those looking for undervalued stocks?

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image for news GILD or VRTX: Which Is the Better Value Stock Right Now?
3 Stocks That Could Trounce the Market in 2025
LLY, SMMT, VRTX
Published: February 17, 2025 by: The Motley Fool
Sentiment: Positive

If you're content with market-level returns, investing in an exchange-traded fund (ETF) is the way to go. But if not, you'll need to find stocks that hold the potential to pack more punch.

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image for news 3 Stocks That Could Trounce the Market in 2025
Vertex Pharmaceuticals Incorporated (VRTX) Is a Trending Stock: Facts to Know Before Betting on It
VRTX
Published: February 14, 2025 by: Zacks Investment Research
Sentiment: Positive

Vertex (VRTX) has been one of the stocks most watched by Zacks.com users lately. So, it is worth exploring what lies ahead for the stock.

Read More
image for news Vertex Pharmaceuticals Incorporated (VRTX) Is a Trending Stock: Facts to Know Before Betting on It
Levi & Korsinsky Announces an Investigation on Behalf of Vertex Pharmaceuticals Incorporated (VRTX) Shareholders Who May Have Been Affected by Fraud
VRTX
Published: February 14, 2025 by: Accesswire
Sentiment: Neutral

NEW YORK, NY / ACCESS Newswire / February 14, 2025 / Levi & Korsinsky notifies investors that it has commenced an investigation of Vertex Pharmaceuticals Incorporated ("Vertex Pharmaceuticals") (NASDAQ:VRTX) concerning possible violations of federal securities laws. On December 19, 2024, the company reported disappointing results from its RewinD-LB Phase 2b clinical trial for the pain drug suzetrigine.

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image for news Levi & Korsinsky Announces an Investigation on Behalf of Vertex Pharmaceuticals Incorporated (VRTX) Shareholders Who May Have Been Affected by Fraud
The Ultimate Healthcare Stock to Buy With $500 Right Now
VRTX
Published: February 14, 2025 by: The Motley Fool
Sentiment: Positive

Healthcare isn't the hottest sector these days. While the S&P 500 has soared nearly 21% over the last 12 months, healthcare stocks as a group are barely in positive territory.

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image for news The Ultimate Healthcare Stock to Buy With $500 Right Now
Vertex Pharmaceuticals Gets a Huge FDA Approval Which Could Send the Stock Skyrocketing
VRTX
Published: February 14, 2025 by: The Motley Fool
Sentiment: Positive

Obtaining approval from the U.S. Food and Drug Administration (FDA) for a key medication can be a huge catalyst for a healthcare stock. It opens up new growth opportunities for the business.

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image for news Vertex Pharmaceuticals Gets a Huge FDA Approval Which Could Send the Stock Skyrocketing
Vertex Pharmaceuticals Incorporated Investigation Ongoing: Contact Levi & Korsinsky About Potential Securities Fraud Allegations - VRTX
VRTX
Published: February 12, 2025 by: Accesswire
Sentiment: Neutral

NEW YORK, NY / ACCESS Newswire / February 12, 2025 / Levi & Korsinsky notifies investors that it has commenced an investigation of Vertex Pharmaceuticals Incorporated ("Vertex Pharmaceuticals") (NASDAQ:VRTX) concerning possible violations of federal securities laws. On December 19, 2024, the company reported disappointing results from its RewinD-LB Phase 2b clinical trial for the pain drug suzetrigine.

Read More
image for news Vertex Pharmaceuticals Incorporated Investigation Ongoing: Contact Levi & Korsinsky About Potential Securities Fraud Allegations - VRTX
Calls of the Day: Charles Schwab, Vertex Pharma and Transocean
RIG, VRTX
Published: February 11, 2025 by: CNBC Television
Sentiment: Neutral

The Investment Committee debate the latest Calls of the Day.

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image for news Calls of the Day: Charles Schwab, Vertex Pharma and Transocean
VRTX's Q4 Earnings Miss Mark, Revenues Beat on Higher Product Sales
VRTX
Published: February 11, 2025 by: Zacks Investment Research
Sentiment: Negative

Vertex reports mixed fourth-quarter 2024 results as earnings miss estimates while revenues beat the same. Trikafta/Kaftrio drive year-over-year sales.

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image for news VRTX's Q4 Earnings Miss Mark, Revenues Beat on Higher Product Sales
Vertex Pharmaceuticals Incorporated (VRTX) Q4 2024 Earnings Call Transcript
VRTX
Published: February 10, 2025 by: Seeking Alpha
Sentiment: Neutral

Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX ) Q4 2024 Earnings Conference Call February 10, 2025 4:30 PM ET Company Participants Susie Lisa - Senior Vice President, Investor Relations Reshma Kewalramani - President and Chief Executive Office Stuart Arbuckle - Chief Operating Officer Charlie Wagner - Chief Financial Officer Conference Call Participants Salveen Richter - Goldman Sachs Evan Seigerman - BMO Capital Markets Jessica Fye - JPMorgan Geoff Meacham - Citibank Michael Yee - Jefferies William Pickering - Bernstein Liisa Bayko - Evercore ISI Phil Nadeau - TD Cowen Eliana Merle - UBS Tazeen Ahmad - Bank of America Dave Risinger - Leerink …

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image for news Vertex Pharmaceuticals Incorporated (VRTX) Q4 2024 Earnings Call Transcript
Markets Steady, Positive; Q4 Earnings Keep Rolling
CLF, LSCC, SMCI, VRTX
Published: February 10, 2025 by: Zacks Investment Research
Sentiment: Neutral

Indexes mostly shrugged off +25% steel tariffs announced by President Trump; VRTX, LSCC report for Q4.

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image for news Markets Steady, Positive; Q4 Earnings Keep Rolling
Vertex's Revenue Surges but EPS Slips
VRTX
Published: February 10, 2025 by: The Motley Fool
Sentiment: Positive

Vertex Pharmaceuticals (VRTX 0.14%), known for its innovative treatments, reported its fourth-quarter earnings on Feb. 10. The company's revenue increased significantly to $2.91 billion, which was above analysts' expectations of $2.78 billion.

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image for news Vertex's Revenue Surges but EPS Slips
Vertex Pharmaceuticals' Revenue Forecast Tops Expectations
VRTX
Published: February 10, 2025 by: Investopedia
Sentiment: Positive

Vertex Pharmaceuticals (VRTX) reported fourth-quarter revenue and offered an outlook for 2025 that topped analysts' expectations.

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image for news Vertex Pharmaceuticals' Revenue Forecast Tops Expectations
Will These 5 Biotech Bigwig Stocks Surpass Q4 Earnings Forecast?
ALNY, BIIB, GILD, MRNA, VRTX
Published: February 10, 2025 by: Zacks Investment Research
Sentiment: Positive

We focus on biotech stocks like VRTX, GILD, BIIB, ALNY and MRNA, which are scheduled to report this week.

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image for news Will These 5 Biotech Bigwig Stocks Surpass Q4 Earnings Forecast?

About Vertex Pharmaceuticals Incorporated (VRTX)

  • IPO Date 1991-07-24
  • Website https://www.vrtx.com
  • Industry Biotechnology
  • CEO Dr. Reshma Kewalramani FASN, M.D.
  • Employees 6100

Vertex Pharmaceuticals Incorporated, a biotechnology company, engages in developing and commercializing therapies for treating cystic fibrosis. The company markets SYMDEKO/SYMKEVI, ORKAMBI, and KALYDECO to treat patients with cystic fibrosis who have specific mutations in their cystic fibrosis transmembrane conductance regulator gene; and TRIKAFTA for the treatment of patients with CF 6 years of age or older who have at least one F508del mutation. Its pipeline includes VX-864 for the treatment of AAT deficiency, which is in Phase 2 clinical trial; VX-147 for the treatment of APOL1-mediated focal segmental glomerulosclerosis, or FSGS, and other serious kidney diseases which is in Phase 2 clinical trial; VX- 880, treatment for Type 1 Diabetes which is in Phase 1/2 clinical trial; VX-548, a NaV1.8 inhibitor for treatments of acute, neuropathic, musculoskeletal pain which is in Phase 2 clinical trial; and CTX001 for the treatment severe SCD and TDT which is in Phase 3 clinical trial. The company sells its products primarily to specialty pharmacy and specialty distributors in the United States, as well as specialty distributors and retail chains, and hospitals and clinics internationally. It has collaborations with Affinia Therapeutics, Inc.; Arbor Biotechnologies, Inc.; CRISPR Therapeutics AG.; Kymera Therapeutics, Inc.; Mammoth Biosciences, Inc.; Moderna, Inc.; Obsidian Therapeutics, Inc.; and Skyhawk Therapeutics, Inc.; as well as Ribometrix, Inc.; Genomics plc; Merck KGaA; Darmstadt, Germany, and X-Chem, Inc. Vertex Pharmaceuticals Incorporated was founded in 1989 and is headquartered in Boston, Massachusetts.