Axsome Therapeutics, Inc. (AXSM)

US — Healthcare Sector
Peers: NUVL  MTSR  MRUS  ABVX  CYTK  RYTM  ARWR  CRSP  PCVX  JAZZ 

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Key Metrics & Ratings

  • symbol AXSM
  • Rev/Share 11.2204
  • Book/Share 1.4739
  • PB 103.5691
  • Debt/Equity 2.9311
  • CurrentRatio 1.5691
  • ROIC -0.5573

 

  • MktCap 7695489496.0
  • FreeCF/Share -2.0118
  • PFCF -76.4708
  • PE -33.2677
  • Debt/Assets 0.3229
  • DivYield 0
  • ROE -3.5721

 

  • Rating C-
  • Score 1
  • Recommendation Strong Sell
  • P/E Score 1
  • DCF Score 3
  • P/B Score 1
  • D/E Score 1

Recent Analyst Ratings

Type Ticker Analyst Firm Previous Rating Current Rating Previous Price Target Current Price Target Date
Initiation AXSM B. Riley Securities -- Buy -- $179 Oct. 1, 2025
Resumed AXSM Wells Fargo -- Overweight -- $163 Sept. 3, 2025
Resumed AXSM Morgan Stanley -- Overweight -- $190 July 3, 2025
Initiation AXSM Oppenheimer -- Outperform -- $185 June 3, 2025
Initiation AXSM Jefferies -- Buy -- $200 April 7, 2025
Initiation AXSM Deutsche Bank -- Buy -- $176 Feb. 11, 2025
Reiterated AXSM Mizuho -- Outperform $124 $122 Dec. 31, 2024
Initiation AXSM Wells Fargo -- Overweight -- $140 Sept. 3, 2024

News

Kuehn Law Encourages Investors of Axsome Therapeutics, Inc. to Contact Law Firm
AXSM
Published: April 08, 2025 by: PRNewsWire
Sentiment: Neutral

NEW YORK , April 8, 2025 /PRNewswire/ -- Kuehn Law, PLLC, a shareholder litigation law firm, is investigating whether certain officers and directors of Axsome Therapeutics, Inc. (NASDAQ: AXSM) breached their fiduciary duties to shareholders. According to a federal securities lawsuit, Insiders at Axsome caused the company to misrepresent or fail to disclose (i) Axsome's chemistry, manufacturing, and control ("CMC") practices were deficient with respect to AXS-07 and its manufacturing process; (ii) as a result, Axsome was unlikely to submit the AXS-07 NDA on its initially represented timeline; (iii) the foregoing CMC issues remained unresolved at the time that the …

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image for news Kuehn Law Encourages Investors of Axsome Therapeutics, Inc. to Contact Law Firm
Axsome Therapeutics Presents Positive Pivotal Phase 3 Results of the ACCORD-2 Trial of AXS-05 in Alzheimer's Disease Agitation and the SYMPHONY Trial of AXS-12 in Narcolepsy at the 2025 American Academy of Neurology (AAN) Annual Meeting
AXSM
Published: April 04, 2025 by: GlobeNewsWire
Sentiment: Neutral

Late-breaking oral presentation of results from the positive pivotal ACCORD-2 Phase 3 trial of AXS-05 in Alzheimer's disease agitation

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image for news Axsome Therapeutics Presents Positive Pivotal Phase 3 Results of the ACCORD-2 Trial of AXS-05 in Alzheimer's Disease Agitation and the SYMPHONY Trial of AXS-12 in Narcolepsy at the 2025 American Academy of Neurology (AAN) Annual Meeting
AXSM Stock Down on Top-Line Data From Depression Study on Solriamfetol
AXSM
Published: April 02, 2025 by: Zacks Investment Research
Sentiment: Negative

Axsome's phase III PARADIGM study evaluating solriamfetol in major depressive disorder fails to show a statistically significant change in the primary endpoint.

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image for news AXSM Stock Down on Top-Line Data From Depression Study on Solriamfetol
Why Shares of Axsome Therapeutics Slumped Today
AXSM
Published: April 01, 2025 by: The Motley Fool
Sentiment: Negative

Shares of biopharmaceutical company Axsome Therapeutics (AXSM -6.29%) had declined 6% at 11 a.m. ET today. The slump comes after the company announced the results of a phase 3 trial of solriamfetol (brand name Sunosi) in major depressive disorder (MDD).

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image for news Why Shares of Axsome Therapeutics Slumped Today
AXSM Stock Down Despite ADHD Study Meeting Primary Endpoint
AXSM
Published: March 26, 2025 by: Zacks Investment Research
Sentiment: Negative

Axsome's phase III FOCUS study, evaluating solriamfetol for treating attention deficit hyperactivity disorder, meets its primary and key secondary endpoints.

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image for news AXSM Stock Down Despite ADHD Study Meeting Primary Endpoint
Axsome: The Alzheimer's Agitation Program For AXS-05
AXSM
Published: March 21, 2025 by: Seeking Alpha
Sentiment: Positive

Axsome's AXS-05 shows strong efficacy in treating Alzheimer's Disease Agitation, with significant CMAI score reductions in multiple Phase 3 trials. The FDA has greenlit Axsome to submit an sNDA for AXS-05 without requiring new trials, based on robust existing data. AXS-05 demonstrates a favorable safety profile with low discontinuation rates due to adverse events, unlike competitors such as AVP-786 and brexpiprazole.

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image for news Axsome: The Alzheimer's Agitation Program For AXS-05
Will Auvelity & Other Drugs Aid AXSM's Growth Amid Stiff Competition?
AXSM
Published: March 14, 2025 by: Zacks Investment Research
Sentiment: Positive

Axsome's depression drug, Auvelity, is driving the top line while Sunosi diversifies its business. The recent FDA nod for Symbravo also bodes well.

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image for news Will Auvelity & Other Drugs Aid AXSM's Growth Amid Stiff Competition?
AXSM Settles Sunosi Patent Litigation With Hikma Pharmaceuticals
AXSM
Published: March 06, 2025 by: Zacks Investment Research
Sentiment: Positive

Axsome enters into a settlement agreement with Hikma Pharmaceuticals to resolve a patent litigation related to Sunosi.

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image for news AXSM Settles Sunosi Patent Litigation With Hikma Pharmaceuticals
Axsome Says Symbravo Hits Primary Goal In Late-Stage Migraine Trial In Patients Experiencing Inadequate Response To Commonly Used Drugs
AXSM
Published: February 24, 2025 by: Benzinga
Sentiment: Positive

On Monday, Axsome Therapeutics, Inc. AXSM announced that the EMERGE Phase 3 trial of Symbravo (MoSEIC meloxicam and rizatriptan) in patients experiencing inadequate response to oral CGRP inhibitors (most commonly used drugs for migraine) met its primary endpoint.

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image for news Axsome Says Symbravo Hits Primary Goal In Late-Stage Migraine Trial In Patients Experiencing Inadequate Response To Commonly Used Drugs
Axsome Q4 Loss Wider Than Expected, Auvelity Drives Sales Growth
AXSM
Published: February 18, 2025 by: Zacks Investment Research
Sentiment: Positive

AXSM's fourth-quarter 2024 earnings miss estimates while revenues beat the same. Net product sales rise year over year.

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image for news Axsome Q4 Loss Wider Than Expected, Auvelity Drives Sales Growth
Axsome Settling Teva Patent Litigation Is Another Positive Catalyst -- Upgrade
AXSM, TEVA
Published: February 11, 2025 by: Seeking Alpha
Sentiment: Positive

Axsome Therapeutics, Inc.'s stock has surged over 30% since my last “Hold” rating, driven by key catalysts like the litigation settlement with Teva Pharmaceuticals, announced today. Axsome's Auvelity and Sunosi are crucial, with Auvelity expected to generate over 75% of 2025 revenues; as such, today's news is a significant win. Despite high competition in MDD and other markets, Axsome's pipeline, including AXS-07 and AXS-12, shows potential for substantial revenue growth.

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image for news Axsome Settling Teva Patent Litigation Is Another Positive Catalyst -- Upgrade
Why Axsome Therapeutics Stock Is Soaring Today
AXSM
Published: February 11, 2025 by: The Motley Fool
Sentiment: Positive

Shares of Axsome Therapeutics (AXSM 4.36%) are up on Tuesday. The company's stock gained 4.1% as of 10:20 a.m.

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image for news Why Axsome Therapeutics Stock Is Soaring Today
Earnings Preview: Axsome Therapeutics (AXSM) Q4 Earnings Expected to Decline
AXSM
Published: February 11, 2025 by: Zacks Investment Research
Sentiment: Negative

Axsome (AXSM) doesn't possess the right combination of the two key ingredients for a likely earnings beat in its upcoming report. Get prepared with the key expectations.

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image for news Earnings Preview: Axsome Therapeutics (AXSM) Q4 Earnings Expected to Decline
Axsome Stock Surges 20% on Auvelity Patent Settlement With Teva
AXSM
Published: February 11, 2025 by: Zacks Investment Research
Sentiment: Positive

AXSM stock rises 20% as it settles Auvelity patent litigation with Teva, protecting the drug's exclusivity in the United States at least until Sept. 30, 2038.

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image for news Axsome Stock Surges 20% on Auvelity Patent Settlement With Teva
Axsome (AXSM) Surges 20.2%: Is This an Indication of Further Gains?
AXSM
Published: February 11, 2025 by: Zacks Investment Research
Sentiment: Positive

Axsome (AXSM) witnessed a jump in share price last session on above-average trading volume. The latest trend in earnings estimate revisions for the stock doesn't suggest further strength down the road.

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image for news Axsome (AXSM) Surges 20.2%: Is This an Indication of Further Gains?
Why Axsome Therapeutics Stock Is Skyrocketing Today
AXSM
Published: February 10, 2025 by: The Motley Fool
Sentiment: Positive

Shares of Axsome Therapeutics (AXSM 20.22%) are flying higher on Monday. The company's stock is up 24.7% as of 1:10 p.m.

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image for news Why Axsome Therapeutics Stock Is Skyrocketing Today

About Axsome Therapeutics, Inc. (AXSM)

  • IPO Date 2015-11-19
  • Website https://www.axsome.com
  • Industry Biotechnology
  • CEO Herriot Tabuteau
  • Employees 712

Axsome Therapeutics, Inc., a biopharmaceutical company, engages in the development of novel therapies for central nervous system (CNS) disorders in the United States. The company's product pipeline includes AXS-05, a therapeutic for the treatment of major depressive disorder and resistant depression disorders; and that is in the Phase III clinical trial to treat Alzheimer's disease agitation, as well as that has completed phase II clinical trial for the treatment of smoking cessation. It is also developing AXS-07, a novel, oral, rapidly absorbed, multi-mechanistic, and investigational medicine that has completed two Phase III trials for the acute treatment of migraine; AXS-12, a selective and potent norepinephrine reuptake inhibitor, which is in Phase III trial to treat narcolepsy; and AXS-14, a novel, oral, and investigational medicine that is in Phase III trial for the treatment of fibromyalgia. Axsome Therapeutics, Inc. has a research collaboration agreement with Duke University for evaluating AXS-05 in smoking cessation. The company was incorporated in 2012 and is based in New York, New York.