Apellis Pharmaceuticals, Inc. (APLS)

US — Healthcare Sector
Peers: CPRX  KNSA  MLYS  BEAM  CDTX  ADPT  SRRK  IDYA  AGIO  RXRX 

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Key Metrics & Ratings

  • symbol APLS
  • Rev/Share 8.0651
  • Book/Share 3.1833
  • PB 7.0588
  • Debt/Equity 1.185
  • CurrentRatio 3.5441
  • ROIC 0.0881

 

  • MktCap 2843021648.0
  • FreeCF/Share 0.624
  • PFCF 36.1533
  • PE 62.9476
  • Debt/Assets 0.449
  • DivYield 0
  • ROE 0.1894

 

  • Rating C+
  • Score 2
  • Recommendation Sell
  • P/E Score 1
  • DCF Score 1
  • P/B Score 1
  • D/E Score 1

Recent Analyst Ratings

Type Ticker Analyst Firm Previous Rating Current Rating Previous Price Target Current Price Target Date
Initiation APLS Barclays -- Equal Weight -- $24 Jan. 28, 2026
Upgrade APLS BofA Securities Neutral Buy -- $28 Jan. 21, 2026
Initiation APLS Wolfe Research -- Peer Perform -- -- Nov. 6, 2025
Initiation APLS Wells Fargo -- Overweight -- $32 Oct. 15, 2025
Downgrade APLS Goldman Neutral Sell -- $18 Sept. 26, 2025
Downgrade APLS BofA Securities Buy Neutral -- $23 May 9, 2025
Downgrade APLS Raymond James Strong Buy Outperform -- $52 May 9, 2025
Initiation APLS Cantor Fitzgerald -- Overweight -- $44 April 29, 2025
Downgrade APLS Goldman Buy Neutral -- $36 Dec. 17, 2024
Initiation APLS Scotiabank -- Sector Outperform -- -- Oct. 16, 2024

News

Apellis and Sobi Announce EMA Validation of Indication Extension Application for Aspaveli® (pegcetacoplan) for C3G and Primary IC-MPGN
APLS
Published: February 20, 2025 by: GlobeNewsWire
Sentiment: Neutral

WALTHAM, Mass. and STOCKHOLM, Sweden, Feb. 20, 2025 (GLOBE NEWSWIRE) -- Apellis Pharmaceuticals, Inc. (Nasdaq: APLS) and Sobi® (STO:SOBI) today announced the European Medicines Agency (EMA) has validated an indication extension application for Aspaveli® (pegcetacoplan) for the treatment of C3 glomerulopathy (C3G) and primary immune complex membranoproliferative glomerulonephritis (IC-MPGN), which are rare, chronic kidney diseases with no approved treatments.

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image for news Apellis and Sobi Announce EMA Validation of Indication Extension Application for Aspaveli® (pegcetacoplan) for C3G and Primary IC-MPGN
Apellis Pharmaceuticals to Host Conference Call on February 28, 2025, to Discuss Fourth Quarter and Full Year 2024 Financial Results
APLS
Published: February 14, 2025 by: GlobeNewsWire
Sentiment: Neutral

WALTHAM, Mass., Feb. 14, 2025 (GLOBE NEWSWIRE) -- Apellis Pharmaceuticals , Inc. (Nasdaq: APLS) today announced that the company will host a conference call and webcast to discuss its fourth quarter and full year 2024 financial results on Friday, February 28, 2025, at 8:30 a.m.

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image for news Apellis Pharmaceuticals to Host Conference Call on February 28, 2025, to Discuss Fourth Quarter and Full Year 2024 Financial Results

About Apellis Pharmaceuticals, Inc. (APLS)

  • IPO Date 2017-11-09
  • Website https://www.apellis.com
  • Industry Biotechnology
  • CEO Cedric Francois
  • Employees 705

Apellis Pharmaceuticals, Inc., a commercial-stage biopharmaceutical company, focuses on the discovery, development, and commercialization of therapeutic compounds through the inhibition of the complement system for autoimmune and inflammatory diseases. The company's lead product candidate is pegcetacoplan that is in Phase III clinical trials for the treatment of geographic atrophy (GA) in age-related macular degeneration and paroxysmal nocturnal hemoglobinuria (PNH) diseases. It also develops EMPAVELI (systemic pegcetacoplan) for the treatment of cold agglutinin disease (CAD), and hematopoietic stem cell transplantation-associated thrombotic microangiopathy (HSCT-TMA) in hematology; C3 glomerulopathy (C3G), and immune complex membranoproliferative glomerulonephritis (IC-MPGN) in nephrology; and amyotrophic lateral sclerosis (ALS) in neurology. In addition, the company develops APL-2006, a bispecific C3 and VEGF inhibitor for treating complement-mediated disorders; APL-1030, a C3 inhibitor for the treatment of multiple neurodegenerative diseases; and the combination of EMPAVELI and a small interfering RNA, or siRNA for reducing the production of C3 proteins by the liver. It has a collaboration and license agreement with Swedish Orphan Biovitrum AB (publ) to co-develop pegcetacoplan; and a research collaboration with Beam Therapeutics Inc. focused on the use of Beam's base editing technology to discover new treatments for complement-driven diseases. Apellis Pharmaceuticals, Inc. was incorporated in 2009 and is based in Waltham, Massachusetts.