Palvella Therapeutics, Inc. (PVLA)

US — Healthcare Sector
Peers: ABUS  VALN  GHRS  AVBP  GERN  VIR  DNA  IOVA  AVXL  RZLT 

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Key Metrics & Ratings

  • symbol PVLA
  • Rev/Share 0.0
  • Book/Share 4.3229
  • PB 17.5808
  • Debt/Equity 0.0
  • CurrentRatio 7.6692
  • ROIC -0.381

 

  • MktCap 840534540.0
  • FreeCF/Share -1.104
  • PFCF -68.885
  • PE -34.8075
  • Debt/Assets 0.0
  • DivYield 0
  • ROE -0.6978

 

  • Rating C-
  • Score 1
  • Recommendation Strong Sell
  • P/E Score 1
  • DCF Score 3
  • P/B Score 2
  • D/E Score 1

Recent Analyst Ratings

Type Ticker Analyst Firm Previous Rating Current Rating Previous Price Target Current Price Target Date
Initiation PVLA Oppenheimer -- Outperform -- $85 Sept. 9, 2025
Initiation PVLA Raymond James -- Outperform -- $54 Aug. 6, 2025
Initiation PVLA Truist -- Buy -- $56 July 21, 2025
Initiation PVLA Chardan Capital Markets -- Buy -- $50 April 9, 2025
Initiation PVLA Stifel -- Buy -- $45 March 26, 2025
Initiation PVLA Scotiabank -- Sector Outperform -- $50 March 7, 2025
Initiation PVLA Canaccord Genuity -- Buy -- $39 Feb. 20, 2025
Initiation PVLA TD Cowen -- Buy -- $44 Feb. 5, 2025
Initiation PVLA H.C. Wainwright -- Buy -- $38 Dec. 26, 2024
Initiation PVLA Cantor Fitzgerald -- Overweight -- -- Dec. 18, 2024

News

Palvella Therapeutics Announces Scientific Publication in Lymphatic Research and Biology Highlighting Recent Advances in the Pathogenesis of Venous Malformations and the Real-World Use of Rapamycin as an Emerging Targeted Therapy
PVLA
Published: September 17, 2025 by: GlobeNewsWire
Sentiment: Neutral

Recent advances in understanding venous malformation disease pathogenesis highlight the PI3K/AKT/mTOR pathway as a key driver of disease proliferation, spurring real-world off-label use of systemic rapamycin (sirolimus) Publication includes a systematic review of 26 studies evaluating the use of rapamycin for the treatment of venous malformations Study authors highlight unmet clinical need for venous malformations and lack of FDA-approved pharmacologic options while advocating for an FDA-approved targeted topical formulation of rapamycin for patients with cutaneous venous malformations WAYNE, Pa., Sept. 17, 2025 (GLOBE NEWSWIRE) -- (Nasdaq: PVLA) Palvella Therapeutics, Inc. (Palvella), a clinical-stage biopharmaceutical company focused on developing and commercializing …

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image for news Palvella Therapeutics Announces Scientific Publication in Lymphatic Research and Biology Highlighting Recent Advances in the Pathogenesis of Venous Malformations and the Real-World Use of Rapamycin as an Emerging Targeted Therapy
Palvella Therapeutics Completes Enrollment in Phase 3 SELVA Trial of QTORIN™ Rapamycin for Microcystic Lymphatic Malformations, Exceeding Enrollment Target by Over 25%
PVLA
Published: June 23, 2025 by: GlobeNewsWire
Sentiment: Neutral

Enrollment of 51 subjects highlights significant unmet need in this serious, lifelong genetic disease which currently has no FDA-approved therapies

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image for news Palvella Therapeutics Completes Enrollment in Phase 3 SELVA Trial of QTORIN™ Rapamycin for Microcystic Lymphatic Malformations, Exceeding Enrollment Target by Over 25%
Palvella Therapeutics to Host First Quarter 2025 Financial Results and Corporate Update Conference Call on May 15, 2025
PVLA
Published: May 08, 2025 by: GlobeNewsWire
Sentiment: Neutral

WAYNE, Pa., May 08, 2025 (GLOBE NEWSWIRE) -- (Nasdaq: PVLA) Palvella Therapeutics, Inc. (Palvella), a clinical-stage biopharmaceutical company focused on developing and commercializing novel therapies to treat patients suffering from serious, rare genetic skin diseases for which there are no FDA-approved therapies, today announced that it will report its first quarter 2025 financial results on Thursday, May 15, 2025.

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image for news Palvella Therapeutics to Host First Quarter 2025 Financial Results and Corporate Update Conference Call on May 15, 2025
Palvella Therapeutics Granted Additional U.S. Patent for QTORIN™ Rapamycin for the Treatment of Microcystic Lymphatic Malformations
PVLA
Published: April 22, 2025 by: GlobeNewsWire
Sentiment: Neutral

Fifth issued patent in the U.S. for QTORIN™ rapamycin with anticipated patent life extending into 2038 QTORIN™ rapamycin has the potential to be the first approved therapy and standard of care for microcystic lymphatic malformations in the U.S. WAYNE, Pa., April 22, 2025 (GLOBE NEWSWIRE) -- (Nasdaq: PVLA) Palvella Therapeutics, Inc. (Palvella or “the Company”), a clinical-stage biopharmaceutical company focused on developing and commercializing novel therapies to treat patients suffering from serious, rare genetic skin diseases for which there are no U.S. Food and Drug Administration (FDA)-approved therapies, today announced that the United States Patent and Trademark Office (USPTO) issued …

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image for news Palvella Therapeutics Granted Additional U.S. Patent for QTORIN™ Rapamycin for the Treatment of Microcystic Lymphatic Malformations
Palvella Therapeutics to Present at the TD Cowen 45th Annual Healthcare Conference
PVLA
Published: February 25, 2025 by: GlobeNewsWire
Sentiment: Neutral

WAYNE, Pa., Feb. 25, 2025 (GLOBE NEWSWIRE) -- (Nasdaq: PVLA) Palvella Therapeutics, Inc. (Palvella), a clinical-stage biopharmaceutical company focused on developing and commercializing novel therapies to treat patients suffering from serious, rare genetic skin diseases for which there are no FDA-approved therapies, today announced that its management team will present at the TD Cowen 45th Annual Healthcare Conference on Tuesday March 4, 2025, at 2:30 p.m. ET. A live webcast of the presentation will be available on the Events and Presentations section of Palvella's website at www.palvellatx.com.

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image for news Palvella Therapeutics to Present at the TD Cowen 45th Annual Healthcare Conference

About Palvella Therapeutics, Inc. (PVLA)

  • IPO Date 2015-01-02
  • Website https://palvellatx.com
  • Industry Biotechnology
  • CEO Wesley H. Kaupinen
  • Employees 14

Palvella Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on developing and commercializing novel therapies to treat patients serious and rare genetic skin diseases. Its lead product candidate is QTORIN 3.9% rapamycin anhydrous gel (QTORIN rapamycin) that is in Phase 3 clinical trial for the treatment of microcystic lymphatic malformations, as well as in Phase 2 clinical trial to treat cutaneous venous malformations. It also develops QTORIN rapamycin for the treatment of other mTOR-driven skin diseases. The company is based in Wayne, Pennsylvania.