Madrigal Pharmaceuticals, Inc. (MDGL)

US — Healthcare Sector
Peers: RNA  JAZZ  MRNA  CAI  RYTM  ABVX  TECH  EXEL  BMRN  BAX 

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Key Metrics & Ratings

  • symbol MDGL
  • Rev/Share 42.7204
  • Book/Share 26.8646
  • PB 16.2962
  • Debt/Equity 0.588
  • CurrentRatio 4.0149
  • ROIC -0.3158

 

  • MktCap 9942832562.0
  • FreeCF/Share -8.4701
  • PFCF -52.3252
  • PE -34.0689
  • Debt/Assets 0.2813
  • DivYield 0
  • ROE -0.4376

 

  • Rating C-
  • Score 1
  • Recommendation Strong Sell
  • P/E Score 1
  • DCF Score 3
  • P/B Score 1
  • D/E Score 2

Recent Analyst Ratings

Type Ticker Analyst Firm Previous Rating Current Rating Previous Price Target Current Price Target Date
Initiation MDGL Barclays -- Overweight -- $964 Jan. 28, 2026
Downgrade MDGL Wolfe Research Outperform Peer Perform -- -- Jan. 6, 2026
Upgrade MDGL Cantor Fitzgerald Neutral Overweight -- -- Nov. 5, 2025
Upgrade MDGL BofA Securities Underperform Neutral -- $445 Nov. 3, 2025
Initiation MDGL Truist -- Buy -- $580 Oct. 15, 2025
Resumed MDGL H.C. Wainwright -- Buy -- $500 Sept. 4, 2025
Upgrade MDGL B. Riley Securities Neutral Buy $236 $422 Feb. 28, 2025
Reiterated MDGL H.C. Wainwright -- Buy $400 $405 Feb. 27, 2025

News

Madrigal Pharmaceuticals: Rezdiffra First-Mover Advantage Gains Traction (Upgrade)
MDGL
Published: February 28, 2025 by: Seeking Alpha
Sentiment: Positive

Madrigal Pharmaceuticals, Inc.'s Rezdiffra had a strong launch with $103.3M in Q4 sales and solid liquidity, but GLP-1 competition from Novo and Lilly poses significant future challenges. Madrigal's Phase 3 trial aims to expand Rezdiffra's label to early cirrhosis by 2027, with EMA approval expected in mid-2025. GLP-1s like semaglutide and tirzepatide show promising MASH results, potentially disrupting Rezdiffra's market despite its first-mover advantage.

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image for news Madrigal Pharmaceuticals: Rezdiffra First-Mover Advantage Gains Traction (Upgrade)
Madrigal Q4 Earnings Beat, MASH Drug Sales Drive Top Line, Stock Up
MDGL
Published: February 26, 2025 by: Zacks Investment Research
Sentiment: Positive

MDGL stock is rising as it reports better-than-expected fourth-quarter results, beating earnings and revenue estimates, driven by strong Rezdiffra sales.

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image for news Madrigal Q4 Earnings Beat, MASH Drug Sales Drive Top Line, Stock Up
Madrigal Pharmaceuticals Q4 Earnings Review: Strong Quarter, Even Stronger Outlook
MDGL
Published: February 26, 2025 by: Seeking Alpha
Sentiment: Positive

Madrigal Pharmaceuticals, Inc.'s Rezdiffra, the first approved drug for MASH, showed strong sales growth, with Q4 net sales up 66% to $103.3m. Despite a net loss of $466m in 2024, Madrigal's cash position improved to $931m, and Rezdiffra's market potential remains significant with no current competitors. Positive study data and upcoming European approval could further boost Rezdiffra's market presence, making Madrigal a prime M&A target.

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image for news Madrigal Pharmaceuticals Q4 Earnings Review: Strong Quarter, Even Stronger Outlook
Madrigal Pharmaceuticals Reports Fourth-Quarter and Full-Year 2024 Financial Results and Announces New Two-Year Data Demonstrating Potential Benefit of Rezdiffra™ (resmetirom) in Patients with Compensated MASH Cirrhosis
MDGL
Published: February 26, 2025 by: GlobeNewsWire
Sentiment: Neutral

CONSHOHOCKEN, Pa., Feb. 26, 2025 (GLOBE NEWSWIRE) -- Madrigal Pharmaceuticals, Inc. (NASDAQ:MDGL), a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), today reports fourth-quarter and year-end 2024 financial results and reviews business highlights.

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image for news Madrigal Pharmaceuticals Reports Fourth-Quarter and Full-Year 2024 Financial Results and Announces New Two-Year Data Demonstrating Potential Benefit of Rezdiffra™ (resmetirom) in Patients with Compensated MASH Cirrhosis
Madrigal Pharmaceuticals to Participate in the 45th Annual TD Cowen Health Care Conference
MDGL
Published: February 21, 2025 by: GlobeNewsWire
Sentiment: Neutral

CONSHOHOCKEN, Pa., Feb. 21, 2025 (GLOBE NEWSWIRE) -- Madrigal Pharmaceuticals, Inc. (Nasdaq: MDGL) today announced that the company will participate in the 45th Annual TD Cowen Health Care Conference on Tuesday, March 4, 2025 at 11:10 A.M. ET.

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image for news Madrigal Pharmaceuticals to Participate in the 45th Annual TD Cowen Health Care Conference
Madrigal Pharmaceuticals to Release Fourth-Quarter and Full-Year 2024 Financial Results and Host Webcast on February 26, 2025
MDGL
Published: February 12, 2025 by: GlobeNewsWire
Sentiment: Neutral

CONSHOHOCKEN, Pa., Feb. 12, 2025 (GLOBE NEWSWIRE) -- Madrigal Pharmaceuticals, Inc. (Nasdaq: MDGL) announced today that it will release its fourth-quarter and full-year 2024 financial results on Wednesday, Feb. 26, 2025, prior to the open of the U.S. financial markets.

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image for news Madrigal Pharmaceuticals to Release Fourth-Quarter and Full-Year 2024 Financial Results and Host Webcast on February 26, 2025

About Madrigal Pharmaceuticals, Inc. (MDGL)

  • IPO Date 2007-02-06
  • Website https://www.madrigalpharma.com
  • Industry Biotechnology
  • CEO William J. Sibold
  • Employees 528

Madrigal Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company, focuses on the development and commercialization of therapeutic candidates for the treatment of cardiovascular, metabolic, and liver diseases. Its lead product candidate is resmetirom, a liver-directed selective thyroid hormone receptor-ß agonist, which is in Phase III clinical trials for the treatment of non-alcoholic steatohepatitis. The company also develops MGL-3745, a backup compound to resmetirom. It has research, development, and commercialization agreement with Hoffmann-La Roche. Madrigal Pharmaceuticals, Inc. is headquartered in West Conshohocken, Pennsylvania.