Verastem, Inc. (VSTM)

US — Healthcare Sector
Peers: VKTX  TRVN  KPTI  ACRX  INFI 

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Key Metrics & Ratings

  • symbol VSTM
  • Rev/Share 0.0004
  • Book/Share -0.5987
  • PB -10.7234
  • Debt/Equity -2.2436
  • CurrentRatio 3.5009
  • ROIC -1.3516

 

  • MktCap 352773864.0
  • FreeCF/Share -2.1255
  • PFCF -3.0637
  • PE -2.3361
  • Debt/Assets 0.5525
  • DivYield 0
  • ROE 58.0644

 

  • Rating C+
  • Score 2
  • Recommendation Sell
  • P/E Score 1
  • DCF Score 3
  • P/B Score 1
  • D/E Score 1

Recent Analyst Ratings

Type Ticker Analyst Firm Previous Rating Current Rating Previous Price Target Current Price Target Date
Initiation VSTM Jefferies -- Buy -- $15 April 10, 2025
Reiterated VSTM H.C. Wainwright -- Buy $7 $10 March 24, 2025
Reiterated VSTM BTIG Research -- Buy $13 $20 Dec. 31, 2024
Initiation VSTM Guggenheim -- Buy -- $13 Sept. 30, 2024

News

Verastem Oncology Announces Updated Data from Partner GenFleet Therapeutics' Phase 1 Study in China of GFH375 (VS-7375), an Oral KRAS G12D (ON/OFF) Inhibitor
VSTM
Published: June 02, 2025 by: Business Wire
Sentiment: Neutral

BOSTON--(BUSINESS WIRE)--Verastem Oncology (Nasdaq: VSTM), a biopharmaceutical company committed to advancing new medicines for patients with RAS/MAPK pathway-driven cancers, today announced positive updated data from the dose escalation phase of the Phase 1/2 trial of GFH375 (known as VS-7375 in the U.S.). As of May 16, 2025, 23 efficacy-evaluable patients with pancreatic ductal adenocarcinoma (PDAC) and 12 efficacy-evaluable patients with non-small cell lung cancer (NSCLC) achieved an overall.

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image for news Verastem Oncology Announces Updated Data from Partner GenFleet Therapeutics' Phase 1 Study in China of GFH375 (VS-7375), an Oral KRAS G12D (ON/OFF) Inhibitor
VSTM Stock Soars 22% in a Month on Ovarian Cancer Combo Drug Approval
VSTM
Published: May 28, 2025 by: Zacks Investment Research
Sentiment: Positive

Verastem Oncology jumps 22% on FDA nod for Avmapki Fakzynja, the first approved KRAS-mutant LGSOC therapy, with strong early data in a pancreatic cancer study.

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image for news VSTM Stock Soars 22% in a Month on Ovarian Cancer Combo Drug Approval
Verastem Oncology Announces Positive Updated Results from RAMP 205 Evaluating Avutometinib Plus Defactinib in Combination with Standard-of-Care Chemotherapy in Frontline Metastatic Pancreatic Ductal Adenocarcinoma
VSTM
Published: May 22, 2025 by: Business Wire
Sentiment: Neutral

BOSTON--(BUSINESS WIRE)--Verastem Oncology (Nasdaq: VSTM), a biopharmaceutical company committed to advancing new medicines for patients with RAS/MAPK pathway-driven cancers, today announced positive updated safety and efficacy results from the RAMP 205 Phase 1/2 trial evaluating avutometinib plus defactinib in combination with gemcitabine and Nab-paclitaxel in the front-line for patients with metastatic pancreatic ductal adenocarcinoma (PDAC). As of April 25, 2025, patients in the dose level 1.

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image for news Verastem Oncology Announces Positive Updated Results from RAMP 205 Evaluating Avutometinib Plus Defactinib in Combination with Standard-of-Care Chemotherapy in Frontline Metastatic Pancreatic Ductal Adenocarcinoma
U.S. FDA approves Verastem's cancer therapy
VSTM
Published: May 08, 2025 by: Reuters
Sentiment: Positive

The U.S. Food and Drug Administration has approved Verastem's combination therapy for patients with a type of ovarian cancer who have received prior treatment, the regulator said on Thursday.

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image for news U.S. FDA approves Verastem's cancer therapy
Verastem Oncology Announces $75 million Private Placement
VSTM
Published: April 25, 2025 by: Business Wire
Sentiment: Neutral

BOSTON--(BUSINESS WIRE)--Verastem Oncology (Nasdaq: VSTM), a biopharmaceutical company committed to advancing new medicines for patients with RAS/MAPK pathway-driven cancers, today announced that it has entered into a securities purchase agreement with certain institutional and accredited investors for a private placement of approximately $24 million of shares of its common stock at a price of $7.00 per share and, in lieu of common stock to certain investors, $51 million of pre-funded warrants.

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image for news Verastem Oncology Announces $75 million Private Placement
Top Cancer Stocks to Buy to Boost Your Portfolio's Health
PYXS, RLAY, VSTM
Published: April 16, 2025 by: Zacks Investment Research
Sentiment: Positive

If the cancer space appeals to you, it's time to consider stocks like Pyxis Oncology, Verastem Oncology and Relay Therapeutics.

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image for news Top Cancer Stocks to Buy to Boost Your Portfolio's Health
Verastem: RAMP-203 Study Could Be Next Big Win For Avutometinib Combination
VSTM
Published: April 10, 2025 by: Seeking Alpha
Sentiment: Positive

Verastem, Inc.'s priority review PDUFA date of avutometinib + defactinib for treatment of patients with recurrent LGSOC is expected June 30th of 2025; At this time, no FDA advisory committee to be held. The global Non-small cell lung cancer market size is projected to reach $36.9 billion by 2031; KRAS G12C variant is the most common KRAS mutation, accounting for 13% of NSCLC cases. Data from phase 1/2 RAMP-203 study, using avutometinib + LUMAKRAS with or without defacinib to treat patients with KRAS G12C mutant NSCLC, is expected to be presented 2nd half of 2025.

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image for news Verastem: RAMP-203 Study Could Be Next Big Win For Avutometinib Combination
Wall Street Analysts Believe Verastem (VSTM) Could Rally 100.94%: Here's is How to Trade
VSTM
Published: March 27, 2025 by: Zacks Investment Research
Sentiment: Positive

The average of price targets set by Wall Street analysts indicates a potential upside of 100.9% in Verastem (VSTM). While the effectiveness of this highly sought-after metric is questionable, the positive trend in earnings estimate revisions might translate into an upside in the stock.

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image for news Wall Street Analysts Believe Verastem (VSTM) Could Rally 100.94%: Here's is How to Trade

About Verastem, Inc. (VSTM)

  • IPO Date 2012-01-27
  • Website https://www.verastem.com
  • Industry Biotechnology
  • CEO Mr. Daniel W. Paterson
  • Employees 78

Verastem, Inc., a development-stage biopharmaceutical company, focusing on developing and commercializing drugs for the treatment of cancer. Its product in development includes VS-6766, a dual rapidly accelerated fibrosarcoma (RAF)/mitogen-activated protein kinase (MEK) clamp that blocks MEK kinase activity and the ability of RAF to phosphorylate MEK. The company also engages in developing RAMP 201, an adaptive two-part multicenter, parallel cohort, randomized open label trial to evaluate the efficacy and safety of VS-6766 and in combination with defactinib, an oral small molecule inhibitor of focal adhesion kinase (FAK) in patients with recurrent low grade serous ovarian cancer; and RAMP 202, which is in Phase 2 trial to evaluate the safety of VS-6766 in combination with defactinib in patients with KRAS and BRAF mutant non-small cell lung cancer following treatment with a platinum-based regimen and immune checkpoint inhibitor. Verastem, Inc. has license agreements with Chugai Pharmaceutical Co., Ltd. for the development, commercialization, and manufacture of products containing VS-6766; and Pfizer Inc. to research, develop, manufacture, and commercialize products containing Pfizer's inhibitors of FAK for therapeutic, diagnostic and prophylactic uses in humans. In addition, it has clinical collaboration agreement with Amgen, Inc. to evaluate the combination of VS-6766 with Amgen's KRAS-G12C inhibitor LUMAKRASTM which in Phase 1/2 trial entitled RAMP 203. The company was incorporated in 2010 and is headquartered in Needham, Massachusetts.