Sionna Therapeutics, Inc. (SION)
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- symbol SION
- Rev/Share 0.0
- Book/Share 7.6258
- PB 3.119
- Debt/Equity 0.0275
- CurrentRatio 35.3306
- ROIC -0.2054
- MktCap 1049865714.0
- FreeCF/Share -1.2802
- PFCF -18.5883
- PE -17.8002
- Debt/Assets 0.0262
- DivYield 0
- ROE -0.6272
- Rating C+
- Score 2
- Recommendation Sell
- P/E Score 1
- DCF Score 3
- P/B Score 3
- D/E Score 4
Recent Analyst Ratings
| Type | Ticker | Analyst Firm | Previous Rating | Current Rating | Previous Price Target | Current Price Target | Date |
|---|---|---|---|---|---|---|---|
| Initiation | SION | Raymond James | -- | Strong Buy | -- | $45 | Sept. 3, 2025 |
| Initiation | SION | RBC Capital Mkts | -- | Sector Perform | -- | $22 | Sept. 3, 2025 |
| Initiation | SION | Guggenheim | -- | Buy | -- | $45 | March 4, 2025 |
| Initiation | SION | Stifel | -- | Buy | -- | $32 | March 4, 2025 |
| Initiation | SION | TD Cowen | -- | Buy | -- | -- | March 4, 2025 |
News
Stock Picks From Seeking Alpha's August 2025 New Analysts
Published: September 10, 2025 by: Seeking Alpha
Sentiment: Positive
In August, Seeking Alpha welcomed 26 new analysts. This article introduces them and showcases some of their top picks. Analysts highlighted include The J Thesis, recommending PayPal; Ihor Pohkyton, on Keurig Dr Pepper; and David Hotea, writing about Cleveland-Cliffs—all rated as Buys. Analysts' diverse backgrounds span sectors like financials, semiconductors, and utilities, with investment strategies focusing on value and growth investing and options trading.
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Wall Street Analysts See a 66.51% Upside in Sionna Therapeutics, Inc. (SION): Can the Stock Really Move This High?
Published: September 09, 2025 by: Zacks Investment Research
Sentiment: Positive
The mean of analysts' price targets for Sionna Therapeutics, Inc. (SION) points to a 66.5% upside in the stock. While this highly sought-after metric has not proven reasonably effective, strong agreement among analysts in raising earnings estimates does indicate an upside in the stock.
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Sionna Therapeutics, Inc. (SION) Presents At Morgan Stanley 23rd Annual Global Healthcare Conference (Transcript)
Published: September 08, 2025 by: Seeking Alpha
Sentiment: Neutral
Sionna Therapeutics, Inc. (NASDAQ:SION ) Morgan Stanley 23rd Annual Global Healthcare Conference September 8, 2025 7:00 AM EDT Company Participants Michael Cloonan - President, CEO & Director Charlotte McKee - Chief Medical Officer Elena Ridloff - CFO & Head of Corporate Development Presentation Unknown Analyst Well, welcome, guys. Before we start, I'm just going to read a brief disclaimer.
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Sionna Therapeutics to Participate in Upcoming September Investor Conferences
Published: August 27, 2025 by: GlobeNewsWire
Sentiment: Neutral
WALTHAM, Mass., Aug. 27, 2025 (GLOBE NEWSWIRE) -- Sionna Therapeutics, Inc. (Nasdaq: SION), a clinical-stage biopharmaceutical company on a mission to revolutionize the current treatment paradigm for cystic fibrosis (CF) by developing novel medicines that normalize the function of the cystic fibrosis transmembrane conductance regulator (CFTR) protein, today announced that management will participate in fireside chats at the following upcoming investor events:
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Sionna Therapeutics Reports Second Quarter 2025 Financial Results
Published: August 11, 2025 by: GlobeNewsWire
Sentiment: Neutral
Announced positive Phase 1 data for SION-719 and SION-451 demonstrating both first-in-class NBD1 stabilizers were generally well tolerated and exceeded pharmacokinetic targets Initiation of Phase 2a proof-of-concept trial of SION-719 as an add-on to standard of care in cystic fibrosis patients is on track for the second half of 2025 with topline data expected in mid-2026 Advancement of Phase 1 healthy volunteer trial of SION-451 in two proprietary dual combinations is on track for the second half of 2025 with topline data expected in mid-2026 Maintained strong cash position with approximately $337.3 million in cash and cash equivalents, expected to …
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Sionna Therapeutics Announces Presentation of Preclinical Data that Demonstrate Proprietary Dual Combination Therapies Enable Full CFTR Correction in CFHBE Model
Published: June 06, 2025 by: GlobeNewsWire
Sentiment: Neutral
Data featured in oral presentation and poster session at 48 th European Cystic Fibrosis Conference
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Sionna Therapeutics to Present at the Goldman Sachs 46th Annual Global Healthcare Conference
Published: June 03, 2025 by: GlobeNewsWire
Sentiment: Neutral
WALTHAM, Mass., June 03, 2025 (GLOBE NEWSWIRE) -- Sionna Therapeutics, Inc. (Nasdaq: SION), a clinical-stage biopharmaceutical company on a mission to revolutionize the current treatment paradigm for cystic fibrosis (CF) by developing novel medicines that normalize the function of the cystic fibrosis transmembrane conductance regulator (CFTR) protein, today announced that management will participate in a fireside chat at the Goldman Sachs 46th Annual Healthcare Conference in Miami, Florida on Wednesday, June 11th 2025 at 8:00 a.m.
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Sionna Therapeutics to Present Preclinical Data During Oral Session at the 48th European Cystic Fibrosis Conference
Published: May 22, 2025 by: GlobeNewsWire
Sentiment: Neutral
WALTHAM, Mass., May 22, 2025 (GLOBE NEWSWIRE) -- Sionna Therapeutics, Inc. (Nasdaq: SION), a clinical-stage biopharmaceutical company on a mission to revolutionize the current treatment paradigm for cystic fibrosis (CF) by developing novel medicines that normalize the function of the cystic fibrosis transmembrane conductance regulator (CFTR) protein, today announced that preclinical data assessing combinations of Sionna's nucleotide-binding domain 1 (NBD1) stabilizers, SION-451 and SION-719, with complementary Sionna CFTR modulators, galicaftor (SION-2222) and SION-109, will be featured in an oral presentation at the European Cystic Fibrosis Society's (ECFS) 48th European Cystic Fibrosis Conference, being held June 4-7, 2025 in Milan, Italy.
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Sionna Therapeutics Reports First Quarter 2025 Financial Results
Published: May 12, 2025 by: GlobeNewsWire
Sentiment: Neutral
Phase 1 dosing completed for NBD1 stabilizers SION-719 & SION-451; both compounds continue to be generally well tolerated Phase 1 topline data anticipated this quarter On track to initiate Phase 2a proof-of-concept trial and at least one dual combination MAD trial in the second half of 2025; topline data for both anticipated in mid-2026 Strong cash position following completed upsized IPO, with approximately $354.7 million in cash and cash equivalents, expected to fund operations into 2028 WALTHAM, Mass., May 12, 2025 (GLOBE NEWSWIRE) -- Sionna Therapeutics, Inc. (Nasdaq: SION), a clinical-stage biopharmaceutical company on a mission to revolutionize the current …
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Sionna Therapeutics Reports Fourth Quarter and Full Year 2024 Financial Results
Published: March 20, 2025 by: GlobeNewsWire
Sentiment: Neutral
Phase 1 MAD dosing completed for SION-451 and final MAD cohort of SION-719 planned; Interim data in healthy volunteers show potential to provide clinically meaningful benefit to CF patients. Topline data anticipated in first half of 2025
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Sionna Therapeutics to Present at the 45th Annual TD Cowen Health Care Conference
Published: February 24, 2025 by: GlobeNewsWire
Sentiment: Neutral
BOSTON, Feb. 24, 2025 (GLOBE NEWSWIRE) -- Sionna Therapeutics, Inc. (Nasdaq: SION), a clinical-stage biopharmaceutical company on a mission to revolutionize the current treatment paradigm for cystic fibrosis (CF) by developing novel medicines that normalize the function of the cystic fibrosis transmembrane conductance regulator (CFTR) protein, today announced that management will present at the 45th Annual TD Cowen Health Care Conference on Monday, March 3, 2025 at 3:10 p.m. ET.
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About Sionna Therapeutics, Inc. (SION)
- IPO Date 2025-02-07
- Website https://www.sionnatx.com
- Industry Biotechnology
- CEO Michael Cloonan
- Employees 41