SION

Sionna Therapeutics, Inc. Common Stock
NASDAQHEALTHCAREBIOTECHNOLOGY

Key Statistics

Market Cap
$2.10B
P/E Ratio
EPS
$-1.91
Beta
52W High
$51.56
52W Low
$16.38
50-Day MA
$41.23
200-Day MA
$39.57
Dividend Yield
Profit Margin
0.00%
Forward P/E
PEG Ratio

About Sionna Therapeutics, Inc. Common Stock

Sionna Therapeutics, Inc. is an innovative biotechnology company focused on developing advanced therapies for neurodegenerative disorders, notably Alzheimer's and Parkinson's diseases linked to protein misfolding. The company boasts a robust pipeline supported by proprietary technologies aimed at addressing substantial unmet medical needs within this urgent therapeutic space. Through strategic partnerships and a strong commitment to research and development, Sionna is well-positioned to become a leader in the biopharmaceutical sector, dedicated to enhancing patient outcomes and overall quality of life with its groundbreaking neurological treatments.

Official WebsiteUSAFY End: December

Fundamentals

Revenue (TTM)0
Gross Profit (TTM)0
EBITDA$-98.28M
Operating Margin0.00%
Return on Equity-26.70%
Return on Assets-18.30%
Revenue/Share (TTM)$0.00
Book Value$6.39
Price-to-Book7.11
Price-to-Sales (TTM)
EV/Revenue-
EV/EBITDA
Quarterly Earnings Growth (YoY)0.00%
Quarterly Revenue Growth (YoY)0.00%
Shares Outstanding$45.15M
Float$16.76M
% Insiders6.85%
% Institutions100.29%

Historical Volatility

HV 10-Day
76.38%
HV 20-Day
65.97%
HV 30-Day
59.56%
HV 60-Day
67.07%
HV Rank
7.5%

Volatility is currently expanding

Analyst Ratings

Consensus ($51.60 target)
1
Strong Buy
8
Buy
1
Hold
1
Strong Sell

Latest News

Sionna Therapeutics: NBD1 Stabilization Could Redefine Cystic Fibrosis Treatment

Sionna Therapeutics targets cystic fibrosis with a novel NBD1 stabilization mechanism, aiming to enhance CFTR function beyond current standards. SION-719 as an add-on to Trikafta and SION-451 dual combinations both approach pivotal clinical readouts in summer 2026, offering dual strategic paths. Sionna's $289.9M cash runway extends to 2028, supporting critical proof-of-concept milestones without near-term financing risk.

Seeking Alpha6/30/2026Positive
Sionna Therapeutics to Participate in Upcoming June 2026 Investor Conferences

WALTHAM, Mass., May 27, 2026 (GLOBE NEWSWIRE) -- Sionna Therapeutics, Inc. (Nasdaq: SION), a clinical-stage biopharmaceutical company on a mission to revolutionize the current treatment paradigm for cystic fibrosis (CF), today announced that management will participate in the following upcoming investor events:

GlobeNewsWire5/27/2026Neutral
Sionna Therapeutics to Participate in the 2026 RBC Capital Markets Global Healthcare Conference

WALTHAM, Mass., May 13, 2026 (GLOBE NEWSWIRE) -- Sionna Therapeutics, Inc. (Nasdaq: SION), a clinical-stage biopharmaceutical company on a mission to revolutionize the current treatment paradigm for cystic fibrosis (CF), today announced that management will participate in a fireside chat at the 2026 RBC Capital Markets Global Healthcare Conference on Wednesday, May 20th, 2026, at 2:05 p.m. ET.

GlobeNewsWire5/13/2026Neutral
Sionna Therapeutics Reports First Quarter 2026 Financial Results

Enrollment completed in the PreciSION CF Phase 2a proof-of-concept trial evaluating NBD1 stabilizer SION-719 as an add-on to standard of care in participants with cystic fibrosis; topline data on track for the summer of 2026 Ongoing Phase 1 trial evaluating NBD1 stabilizer SION-451 in proprietary dual combinations with SION-2222 and with SION-109 in healthy volunteers is also on track for topline data in the summer of 2026 Maintained strong cash position with approximately $289.9 million in cash and cash equivalents, expected to fund operations into 2028 WALTHAM, Mass., May 12, 2026 (GLOBE NEWSWIRE) -- Sionna Therapeutics, Inc. (Nasdaq: SION), a clinical-stage biopharmaceutical company on a mission to revolutionize the current treatment paradigm for cystic fibrosis (CF) today reported financial results for the first quarter ended March 31, 2026, and provided a business update.

GlobeNewsWire5/12/2026Neutral
Sionna Therapeutics to Participate in the Raymond James 2026 Biotech Innovation Symposium

WALTHAM, Mass., April 07, 2026 (GLOBE NEWSWIRE) -- Sionna Therapeutics, Inc. (Nasdaq: SION), a clinical-stage biopharmaceutical company on a mission to revolutionize the current treatment paradigm for cystic fibrosis (CF) by developing novel medicines that normalize the function of the cystic fibrosis transmembrane conductance regulator (CFTR) protein, today announced that management will participate in one-on-one investor meetings at the Raymond James 2026 Biotech Innovation Symposium on Tuesday, April 14th, 2026.

GlobeNewsWire4/7/2026Neutral

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Data last updated: 7/29/2026