Sionna Therapeutics, Inc. (SION)

US — Healthcare Sector
Peers:

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Key Metrics & Ratings

  • symbol SION
  • Rev/Share 0.0
  • Book/Share 13.2264
  • PB 1.212
  • Debt/Equity 0.027
  • CurrentRatio 28.7268
  • ROIC -0.1759

 

  • MktCap 707314020.0
  • FreeCF/Share -1.8398
  • PFCF -14.4553
  • PE -7.6059
  • Debt/Assets 0.0257
  • DivYield 0
  • ROE 2.9747

 

  • Rating C+
  • Score 2
  • Recommendation Sell
  • P/E Score 1
  • DCF Score 3
  • P/B Score 4
  • D/E Score 3

Recent Analyst Ratings

Type Ticker Analyst Firm Previous Rating Current Rating Previous Price Target Current Price Target Date
Initiation SION Guggenheim -- Buy -- $45 March 4, 2025
Initiation SION Stifel -- Buy -- $32 March 4, 2025
Initiation SION TD Cowen -- Buy -- -- March 4, 2025

News

Sionna Therapeutics Announces Presentation of Preclinical Data that Demonstrate Proprietary Dual Combination Therapies Enable Full CFTR Correction in CFHBE Model
SION
Published: June 06, 2025 by: GlobeNewsWire
Sentiment: Neutral

Data featured in oral presentation and poster session at 48 th European Cystic Fibrosis Conference

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image for news Sionna Therapeutics Announces Presentation of Preclinical Data that Demonstrate Proprietary Dual Combination Therapies Enable Full CFTR Correction in CFHBE Model
Sionna Therapeutics to Present at the Goldman Sachs 46th Annual Global Healthcare Conference
SION
Published: June 03, 2025 by: GlobeNewsWire
Sentiment: Neutral

WALTHAM, Mass., June 03, 2025 (GLOBE NEWSWIRE) -- Sionna Therapeutics, Inc. (Nasdaq: SION), a clinical-stage biopharmaceutical company on a mission to revolutionize the current treatment paradigm for cystic fibrosis (CF) by developing novel medicines that normalize the function of the cystic fibrosis transmembrane conductance regulator (CFTR) protein, today announced that management will participate in a fireside chat at the Goldman Sachs 46th Annual Healthcare Conference in Miami, Florida on Wednesday, June 11th 2025 at 8:00 a.m.

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image for news Sionna Therapeutics to Present at the Goldman Sachs 46th Annual Global Healthcare Conference
Sionna Therapeutics to Present Preclinical Data During Oral Session at the 48th European Cystic Fibrosis Conference
SION
Published: May 22, 2025 by: GlobeNewsWire
Sentiment: Neutral

WALTHAM, Mass., May 22, 2025 (GLOBE NEWSWIRE) -- Sionna Therapeutics, Inc. (Nasdaq: SION), a clinical-stage biopharmaceutical company on a mission to revolutionize the current treatment paradigm for cystic fibrosis (CF) by developing novel medicines that normalize the function of the cystic fibrosis transmembrane conductance regulator (CFTR) protein, today announced that preclinical data assessing combinations of Sionna's nucleotide-binding domain 1 (NBD1) stabilizers, SION-451 and SION-719, with complementary Sionna CFTR modulators, galicaftor (SION-2222) and SION-109, will be featured in an oral presentation at the European Cystic Fibrosis Society's (ECFS) 48th European Cystic Fibrosis Conference, being held June 4-7, 2025 in Milan, Italy.

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image for news Sionna Therapeutics to Present Preclinical Data During Oral Session at the 48th European Cystic Fibrosis Conference
Sionna Therapeutics Reports First Quarter 2025 Financial Results
SION
Published: May 12, 2025 by: GlobeNewsWire
Sentiment: Neutral

Phase 1 dosing completed for NBD1 stabilizers SION-719 & SION-451; both compounds continue to be generally well tolerated Phase 1 topline data anticipated this quarter On track to initiate Phase 2a proof-of-concept trial and at least one dual combination MAD trial in the second half of 2025; topline data for both anticipated in mid-2026 Strong cash position following completed upsized IPO, with approximately $354.7 million in cash and cash equivalents, expected to fund operations into 2028 WALTHAM, Mass., May 12, 2025 (GLOBE NEWSWIRE) -- Sionna Therapeutics, Inc. (Nasdaq: SION), a clinical-stage biopharmaceutical company on a mission to revolutionize the current …

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image for news Sionna Therapeutics Reports First Quarter 2025 Financial Results
Sionna Therapeutics Reports Fourth Quarter and Full Year 2024 Financial Results
SION
Published: March 20, 2025 by: GlobeNewsWire
Sentiment: Neutral

Phase 1 MAD dosing completed for SION-451 and final MAD cohort of SION-719 planned; Interim data in healthy volunteers show potential to provide clinically meaningful benefit to CF patients. Topline data anticipated in first half of 2025

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image for news Sionna Therapeutics Reports Fourth Quarter and Full Year 2024 Financial Results
Sionna Therapeutics to Present at the 45th Annual TD Cowen Health Care Conference
SION
Published: February 24, 2025 by: GlobeNewsWire
Sentiment: Neutral

BOSTON, Feb. 24, 2025 (GLOBE NEWSWIRE) -- Sionna Therapeutics, Inc. (Nasdaq: SION), a clinical-stage biopharmaceutical company on a mission to revolutionize the current treatment paradigm for cystic fibrosis (CF) by developing novel medicines that normalize the function of the cystic fibrosis transmembrane conductance regulator (CFTR) protein, today announced that management will present at the 45th Annual TD Cowen Health Care Conference on Monday, March 3, 2025 at 3:10 p.m. ET.

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image for news Sionna Therapeutics to Present at the 45th Annual TD Cowen Health Care Conference

About Sionna Therapeutics, Inc. (SION)

  • IPO Date
  • Website https://www.sionnatx.com/
  • Industry Biotechnology
  • CEO Mr. Michael Cloonan M.B.A.
  • Employees 41

Sionna Therapeutics, Inc. is a biopharmaceutical company. The Company provides treatment paradigm for cystic fibrosis patients by developing medicines that normalize the function of the cystic fibrosis transmembrane conductance regulator.