Lyra Therapeutics, Inc. (LYRA)

US — Healthcare Sector
Peers: CTMX  ASMB  ACHL  NLTX  TIL  NXTC  SPRO  NUVB  CGEM  BOLT  DAWN  AUTL 

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Key Metrics & Ratings

  • symbol LYRA
  • Rev/Share 0.901
  • Book/Share 2.9441
  • PB 3.6276
  • Debt/Equity 8.6147
  • CurrentRatio 2.956
  • ROIC -1.6642

 

  • MktCap 14154631.0
  • FreeCF/Share -43.0267
  • PFCF -0.2501
  • PE -0.1766
  • Debt/Assets 0.5923
  • DivYield 0
  • ROE -4.7437

 

  • Rating C-
  • Score 1
  • Recommendation Strong Sell
  • P/E Score 1
  • DCF Score 1
  • P/B Score 3
  • D/E Score 1

Recent Analyst Ratings

Type Ticker Analyst Firm Previous Rating Current Rating Previous Price Target Current Price Target Date
No ratings available.

News

Lyra Therapeutics (LYRA) Upgraded to Buy: Here's Why
LYRA
Published: June 12, 2025 by: Zacks Investment Research
Sentiment: Positive

Lyra Therapeutics (LYRA) might move higher on growing optimism about its earnings prospects, which is reflected by its upgrade to a Zacks Rank #2 (Buy).

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image for news Lyra Therapeutics (LYRA) Upgraded to Buy: Here's Why
Lyra Stock Soars 356% in a Week on Strong Rhinosinusitis Study Success
LYRA
Published: June 05, 2025 by: Zacks Investment Research
Sentiment: Positive

LYRA skyrockets 356% after its lead nasal implant, LYR-210, meets key goals in a pivotal phase III chronic rhinosinusitis study.

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image for news Lyra Stock Soars 356% in a Week on Strong Rhinosinusitis Study Success
This penny stock just spiked 550% in a day; Time to buy?
LYRA
Published: June 02, 2025 by: Finbold
Sentiment: Positive

Lyra Therapeutics (NASDAQ: LYRA) ‘s shares surged 550% in pre-market trading on Monday following a breakthrough in its drug trials.

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image for news This penny stock just spiked 550% in a day; Time to buy?
Lyra Therapeutics Reports Positive Results from the ENLIGHTEN 2 Phase 3 Trial of LYR-210 Achieving Statistically Significant Results for Primary and Key Secondary Endpoints in the Treatment of Chronic Rhinosinusitis (CRS)
LYRA
Published: June 02, 2025 by: GlobeNewsWire
Sentiment: Neutral

WATERTOWN, Mass., June 02, 2025 (GLOBE NEWSWIRE) -- Lyra Therapeutics, Inc. (Nasdaq: LYRA) (“Lyra” or the “Company”), a clinical-stage biotechnology company developing long-acting, anti-inflammatory sinonasal implants for the treatment of chronic rhinosinusitis (CRS), today announced positive results from the ENLIGHTEN 2 Phase 3 clinical trial of LYR-210 in adult patients with CRS. The ENLIGHTEN 2 trial met its primary endpoint, with LYR-210 demonstrating statistically significant improvement compared to sham control in a composite of the three cardinal symptoms (3CS) of CRS (nasal obstruction, nasal discharge, facial pain/pressure) at week 24 (-1.13; p=0.0078) in patients without nasal polyps.

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image for news Lyra Therapeutics Reports Positive Results from the ENLIGHTEN 2 Phase 3 Trial of LYR-210 Achieving Statistically Significant Results for Primary and Key Secondary Endpoints in the Treatment of Chronic Rhinosinusitis (CRS)
Lyra Therapeutics to Present 52-week Extension Stage Results for ENLIGHTEN 1 Phase 3 Study for LYR-210 for the Treatment of Chronic Rhinosinusitis at COSM 2025
LYRA
Published: May 07, 2025 by: GlobeNewsWire
Sentiment: Neutral

WATERTOWN, Mass., May 07, 2025 (GLOBE NEWSWIRE) -- Lyra Therapeutics, Inc. (Nasdaq: LYRA), (“Lyra” or the “Company”), a clinical-stage biotechnology company developing long-acting, anti-inflammatory sinonasal implants for the treatment of chronic rhinosinusitis (CRS), today announced that the Company plans to present results from the 52-week Extension Stage of the ENLIGHTEN 1 Phase 3 study for LYR-210, the Company's lead product candidate for CRS, at the annual Combined Otolaryngology Spring Meetings (COSM 2025) being held May 14-18 in New Orleans.

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image for news Lyra Therapeutics to Present 52-week Extension Stage Results for ENLIGHTEN 1 Phase 3 Study for LYR-210 for the Treatment of Chronic Rhinosinusitis at COSM 2025
Lyra Therapeutics, Inc. (LYRA) Reports Q1 Loss, Lags Revenue Estimates
LYRA
Published: May 06, 2025 by: Zacks Investment Research
Sentiment: Negative

Lyra Therapeutics, Inc. (LYRA) came out with a quarterly loss of $0.12 per share versus the Zacks Consensus Estimate of a loss of $0.15. This compares to loss of $0.35 per share a year ago.

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image for news Lyra Therapeutics, Inc. (LYRA) Reports Q1 Loss, Lags Revenue Estimates

About Lyra Therapeutics, Inc. (LYRA)

  • IPO Date 2020-05-01
  • Website https://lyratherapeutics.com
  • Industry Biotechnology
  • CEO Dr. Maria Palasis Ph.D.
  • Employees 30

Lyra Therapeutics, Inc., a clinical-stage therapeutics company, focuses on the development and commercialization of novel integrated drug and delivery solutions for the localized treatment of patients with ear, nose, and throat diseases. It's XTreo technology platform is designed to deliver medicines directly to the affected tissue for sustained periods with a single administration. The company's product candidates include LYR-210, an anti-inflammatory implantable drug matrix for the treatment of chronic rhinosinusitis (CRS), which is in Phase II clinical trial; and LYR-220 for CRS patients with and without nasal polyps. The company was formerly known as 480 Biomedical, Inc. and changed its name to Lyra Therapeutics, Inc. in July 2018. Lyra Therapeutics, Inc. was incorporated in 2005 and is headquartered in Watertown, Massachusetts.