APRE

Aprea Therapeutics Inc
NASDAQHEALTHCAREBIOTECHNOLOGY

Key Statistics

Market Cap
$9.41M
P/E Ratio
EPS
$-1.49
Beta
1.56
52W High
$2.22
52W Low
$0.55
50-Day MA
$0.82
200-Day MA
$0.97
Dividend Yield
Profit Margin
0.00%
Forward P/E
PEG Ratio

About Aprea Therapeutics Inc

Aprea Therapeutics, Inc., a clinical-stage biopharmaceutical company, develops and markets cancer therapies that reactivate the mutant p53 tumor suppressor protein. The company is headquartered in Boston, Massachusetts.

Official WebsiteUSAFY End: December

Fundamentals

Revenue (TTM)123,300
Gross Profit (TTM)$-6.05M
EBITDA$-12.56M
Operating Margin-10202.00%
Return on Equity-40.40%
Return on Assets-23.20%
Revenue/Share (TTM)$0.01
Book Value$3.47
Price-to-Book0.22
Price-to-Sales (TTM)76.34
EV/Revenue-
EV/EBITDA0.35
Quarterly Earnings Growth (YoY)0.00%
Quarterly Revenue Growth (YoY)-98.40%
Shares Outstanding$12.38M
Float$7.41M
% Insiders13.46%
% Institutions18.13%

Historical Volatility

HV 10-Day
51.05%
HV 20-Day
81.35%
HV 30-Day
76.04%
HV 60-Day
85.78%
HV Rank
45.2%

Volatility is currently contracting

Analyst Ratings

Consensus ($4.30 target)
1
Strong Buy
3
Buy

Latest News

Aprea Therapeutics Presents Updated Phase 1 Data on WEE1 Inhibitor APR-1051 at ASCO 2026, Demonstrating Early Monotherapy Activity and Manageable Tolerability in Advanced Solid Tumors

Presentation highlights early clinical activity from ACESOT-1051, including partial responses and stable disease in patients across multiple tumor types Manageable tolerability confirmed across cohorts Patient expansion into uterine serous carcinoma and platinum-resistant ovarian cancer underway; dose escalation and backfill expansion expected to complete Q2 2027 DOYLESTOWN, Pa., June 01, 2026 (GLOBE NEWSWIRE) -- Aprea Therapeutics, Inc. (Nasdaq: APRE) (“Aprea”, or the “Company”), a clinical-stage precision medicine oncology company focused on the discovery and development of targeted therapies for patients with biomarker-defined cancers, announces the presentation of a poster “Early results from the first-in-human phase 1 study of WEE1 inhibitor APR-1051 in patients with advanced solid tumors (ACESOT-1051)” on May 30 at the American Society of Clinical Oncology (ASCO) 2026 annual meeting, taking place in Chicago, Illinois.

GlobeNewsWire6/1/2026Neutral
Aprea Therapeutics Reports First Quarter 2026 Financial Results and Provides a Corporate Update

DOYLESTOWN, Pa., May 13, 2026 (GLOBE NEWSWIRE) -- Aprea Therapeutics, Inc. (Nasdaq: APRE) (“Aprea”, or the “Company”), a clinical-stage precision medicine oncology company focused on the discovery and development of targeted therapies for patients with biomarker-defined cancers, today reported financial results for the first quarter ended March 31, 2026, and provided a business update.

GlobeNewsWire5/13/2026Neutral
Aprea Therapeutics to Provide Clinical Update on ACESOT-1051 Phase 1 Trial Evaluating WEE1 Inhibitor, APR-1051, at ASCO 2026 Annual Meeting

DOYLESTOWN, Pa., April 21, 2026 (GLOBE NEWSWIRE) -- Aprea Therapeutics, Inc. (Nasdaq: APRE) (“Aprea”, or the “Company”), a clinical-stage precision medicine oncology company focused on the discovery and development of targeted therapies for patients with biomarker-defined cancers, today announced the acceptance of an abstract “Early results from the first-in-human phase 1 study of WEE1 inhibitor APR-1051 in patients with advanced solid tumors (ACESOT-1051)” at the 2026 American Society of Clinical Oncology (ASCO) Annual Meeting, to take place May 29 - June 2, 2026, in Chicago, IL.

GlobeNewsWire4/21/2026Neutral

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Data last updated: 7/9/2026