Altimmune, Inc. (ALT)

US — Healthcare Sector
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Key Metrics & Ratings

  • symbol ALT
  • Rev/Share 0.0003
  • Book/Share 1.8818
  • PB 1.9184
  • Debt/Equity 0.0
  • CurrentRatio 15.8463
  • ROIC -0.6609

 

  • MktCap 292796270.0
  • FreeCF/Share -1.0633
  • PFCF -3.6449
  • PE -3.0222
  • Debt/Assets 0.0
  • DivYield 0
  • ROE -0.6544

 

  • Rating
  • Score
  • Recommendation
  • P/E Score
  • DCF Score
  • P/B Score
  • D/E Score

Recent Analyst Ratings

Type Ticker Analyst Firm Previous Rating Current Rating Previous Price Target Current Price Target Date
Initiation ALT William Blair -- Market Perform -- -- Feb. 28, 2025
Initiation ALT Stifel -- Buy -- $18 Jan. 8, 2025

News

INVESTOR ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Altimmune, Inc. - ALT
ALT
Published: June 27, 2025 by: PRNewsWire
Sentiment: Neutral

NEW YORK , June 27, 2025 /PRNewswire/ -- Pomerantz LLP is investigating claims on behalf of investors of Altimmune, Inc. ("Altimmune" or the "Company") (NASDAQ: ALT). Such investors are advised to contact Danielle Peyton at [email protected] or 646-581-9980, ext.

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image for news INVESTOR ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Altimmune, Inc. - ALT
Altimmune's Fatty Liver Candidate Faces Differentiation Doubts
ALT
Published: June 27, 2025 by: Benzinga
Sentiment: Negative

On Thursday, Altimmune, Inc. ALT released topline results from the IMPACT Phase 2b trial of pemvidutide in metabolic dysfunction-associated steatohepatitis (MASH).

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image for news Altimmune's Fatty Liver Candidate Faces Differentiation Doubts
Altimmune: FDA Path Forward Remains Despite Mixed MASH Treatment Data Of Pemvidutide
ALT
Published: June 26, 2025 by: Seeking Alpha
Sentiment: Positive

Altimmune, Inc.'s pemvidutide met the primary endpoint of MASH resolution in phase 2b IMPACT study which sets it on a continued development path going forward. The short 24-week trial duration likely limited fibrosis results; longer studies could achieve statistical significance with this endpoint supporting a continued path for phase 3 development. Pemvidutide uniquely delivers both MASH resolution and weight loss, with the lowest adverse event-related discontinuation rates, giving it strong competitive advantages.

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image for news Altimmune: FDA Path Forward Remains Despite Mixed MASH Treatment Data Of Pemvidutide
INVESTOR ALERT: Investigation of Altimmune, Inc. (ALT) Announced by Holzer & Holzer, LLC
ALT
Published: June 26, 2025 by: GlobeNewsWire
Sentiment: Neutral

ATLANTA, June 26, 2025 (GLOBE NEWSWIRE) -- Holzer & Holzer, LLC is investigating whether Altimmune, Inc. (“Altimmune” or the “Company”) (NASDAQ: ALT) complied with federal securities laws. On June 26, 2025, Altimmune announced topline results from the IMPACT Phase 2b trial of pemvidutide in metabolic dysfunction-associated steatohepatitis (MASH), revealing that the trial did not demonstrate statistical significance for the endpoint of improving fibrosis while not worsening MASH. Following this news, the price of the Company's stock dropped.

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image for news INVESTOR ALERT: Investigation of Altimmune, Inc. (ALT) Announced by Holzer & Holzer, LLC
Altimmune shares plunge as MASH drug trial misses key fibrosis endpoint
ALT
Published: June 26, 2025 by: Proactive Investors
Sentiment: Negative

Shares of Altimmune Inc (NASDAQ:ALT) tumbled 55% on Thursday after the company reported mixed results from a mid-stage trial of its experimental drug pemvidutide for metabolic dysfunction-associated steatohepatitis (MASH). The Phase 2b study met one of its primary endpoints, with pemvidutide achieving statistically significant resolution of MASH without worsening of fibrosis at 24 weeks.

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image for news Altimmune shares plunge as MASH drug trial misses key fibrosis endpoint
Altimmune Vs. Viking Therapeutics: Evaluating Pipeline Maturity, And Takeover Potential
ALT, VKTX
Published: June 02, 2025 by: Seeking Alpha
Sentiment: Positive

I rate Altimmune a 'Strong Buy' and Viking Therapeutics a 'Buy' for high-risk, long-term investors. ALT's Pemvidutide stands out for its lean mass protection, visceral fat reduction, and potential in multiple metabolic diseases, making it an attractive acquisition target. VKTX's VK2735 offers strong weight loss efficacy and dual formulation flexibility, but faces tough competition and lacks clear differentiation, despite financial stability.

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image for news Altimmune Vs. Viking Therapeutics: Evaluating Pipeline Maturity, And Takeover Potential
Altimmune: Upcoming MASH Data Could Be High Impact For Business Development Activity
ALT
Published: May 29, 2025 by: Seeking Alpha
Sentiment: Positive

ALT is approach a readout from IMPACT, a phase 2b study of pemvidutide in MASH. MDGL's results with its launch of MASH drug Rezdiffra demonstrate the multi-billion-dollar potential of a MASH drug, although pemvidutide will be compared to other competitors. ALT has also initiated a trial of pemvidutide in alcohol use disorder, with a trial in alcohol liver disease set to start in Q3'25.

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image for news Altimmune: Upcoming MASH Data Could Be High Impact For Business Development Activity
Altimmune Announces Initiation of RECLAIM Phase 2 Trial Evaluating the Efficacy and Safety of Pemvidutide in Alcohol Use Disorder (AUD)
ALT
Published: May 19, 2025 by: GlobeNewsWire
Sentiment: Neutral

GAITHERSBURG, Md., May 19, 2025 (GLOBE NEWSWIRE) -- Altimmune, Inc. (Nasdaq: ALT), a late clinical-stage biopharmaceutical company developing novel peptide-based therapeutics for liver and cardiometabolic diseases, today announced that it has enrolled the first subject in the RECLAIM Phase 2 trial evaluating the efficacy and safety of pemvidutide in subjects with Alcohol Use Disorder (AUD). Pemvidutide is a novel, investigational GLP-1/glucagon dual receptor agonist under development for the treatment of metabolic dysfunction-associated steatohepatitis (MASH), obesity, AUD and alcohol liver disease (ALD). IMPACT, a Phase 2b trial of pemvidutide in MASH, is expected to read out topline data in the second …

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image for news Altimmune Announces Initiation of RECLAIM Phase 2 Trial Evaluating the Efficacy and Safety of Pemvidutide in Alcohol Use Disorder (AUD)
Altimmune, Inc. (ALT) Q1 2025 Earnings Call Transcript
ALT
Published: May 13, 2025 by: Seeking Alpha
Sentiment: Neutral

Altimmune, Inc. (NASDAQ:ALT ) Q1 2025 Earnings Conference Call May 13, 2025 8:30 AM ET Company Participants Lee Roth - President, Burns McClellan, Investor Relations Advisors Vipin Garg - Chief Executive Officer Scott Harris - Chief Medical Officer Greg Weaver - Chief Financial Officer Scot Roberts - Chief Scientific Officer Conference Call Participants Yasmeen Rahimi - Piper Sandler Liisa Bayko - Evercore Roger Song - Jefferies Annabel Samimy - Stifel Mayank Mamtani - B Riley Andy Hsieh - William Blair Operator Good day, ladies and gentlemen, and welcome to Altimmune First Quarter 2025 Financial Results Conference Call. After the speakers' …

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image for news Altimmune, Inc. (ALT) Q1 2025 Earnings Call Transcript
How Much Upside is Left in Altimmune (ALT)? Wall Street Analysts Think 285.86%
ALT
Published: May 09, 2025 by: Zacks Investment Research
Sentiment: Positive

The mean of analysts' price targets for Altimmune (ALT) points to a 285.9% upside in the stock. While this highly sought-after metric has not proven reasonably effective, strong agreement among analysts in raising earnings estimates does indicate an upside in the stock.

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image for news How Much Upside is Left in Altimmune (ALT)? Wall Street Analysts Think 285.86%
Altimmune Presents New Analyses Predicting High Rates of MASH Resolution on Biopsy following Pemvidutide Treatment at the EASL International Liver Congress™
ALT
Published: May 08, 2025 by: GlobeNewsWire
Sentiment: Neutral

MASH Resolution Index (MASHResInd) model highly predictive of MASH resolution MASH Resolution Index (MASHResInd) model highly predictive of MASH resolution

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image for news Altimmune Presents New Analyses Predicting High Rates of MASH Resolution on Biopsy following Pemvidutide Treatment at the EASL International Liver Congress™
Altimmune to Report First Quarter 2025 Financial Results and Provide Business Update on May 13, 2025
ALT
Published: May 06, 2025 by: GlobeNewsWire
Sentiment: Neutral

GAITHERSBURG, Md., May 06, 2025 (GLOBE NEWSWIRE) -- Altimmune, Inc. (Nasdaq: ALT), a late clinical-stage biopharmaceutical company, today announced that it will report its first quarter 2025 financial results on Tuesday, May 13, 2025.

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image for news Altimmune to Report First Quarter 2025 Financial Results and Provide Business Update on May 13, 2025
Altimmune to Present at Upcoming EASL International Liver Congress™ 2025
ALT
Published: May 01, 2025 by: GlobeNewsWire
Sentiment: Neutral

GAITHERSBURG, Md., May 01, 2025 (GLOBE NEWSWIRE) -- Altimmune, Inc. (Nasdaq: ALT), a late clinical-stage biopharmaceutical company developing next-generation peptide-based therapeutics for liver and cardiometabolic diseases, today announced that the Company will present analyses of pemvidutide-treated subjects with metabolic dysfunction-associated steatotic liver disease (MASLD) utilizing the MASH Resolution Index (MASHResInd; Loomba 2024), a highly sensitive non-invasive measure of MASH histologic response, in a poster session at the European Association for the Study of the Liver (EASL) International Liver Congress™ 2025 in Amsterdam, The Netherlands. The abstract will be featured in the conference poster session and poster tour.

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image for news Altimmune to Present at Upcoming EASL International Liver Congress™ 2025
Altimmune to Participate in the Citizens Life Sciences Conference
ALT
Published: April 30, 2025 by: GlobeNewsWire
Sentiment: Neutral

GAITHERSBURG, Md., April 30, 2025 (GLOBE NEWSWIRE) -- Altimmune, Inc. (Nasdaq: ALT), a late clinical-stage biopharmaceutical company, today announced that members of the Company's management team will participate in a fireside chat at the Citizens Life Sciences Conference. Details are as follows:

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image for news Altimmune to Participate in the Citizens Life Sciences Conference
Altimmune Q4 Earnings Review: The Big News Is The MASH With Obesity Data Readout Due Q2
ALT
Published: February 28, 2025 by: Seeking Alpha
Sentiment: Positive

Altimmune's pemvidutide shows promise in treating MASH with obesity, potentially positioning it as a first-in-class drug targeting both liver health and weight loss. Despite past volatility, ALT stock has stabilized, with recent data showing significant weight loss at higher doses, sparking renewed investor interest. Altimmune's Q4 2024 earnings reveal a net loss of $23.2m, with $131.9m in cash, highlighting the company's ongoing financial challenges and reliance on future clinical success.

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image for news Altimmune Q4 Earnings Review: The Big News Is The MASH With Obesity Data Readout Due Q2
Altimmune, Inc. (ALT) Q4 2024 Earnings Call Transcript
ALT
Published: February 27, 2025 by: Seeking Alpha
Sentiment: Neutral

Altimmune, Inc. (NASDAQ:ALT ) Q4 2024 Earnings Conference Call February 27, 2025 8:30 AM ET Company Participants Lee Roth - President, Burns McClellan, Investor Relations Advisors Vipin Garg - Chief Executive Officer Scott Harris - Chief Medical Officer Greg Weaver - Chief Financial Officer Scot Roberts - Chief Scientific Officer Conference Call Participants Yasmeen Rahimi - Piper Sandler Annabel Samimy - Stifel Liisa Bayko - Evercore William Wood - B. Riley Securities Jonathan Wolleben - Citizens JMP Patrick Trucchio - H.C.

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image for news Altimmune, Inc. (ALT) Q4 2024 Earnings Call Transcript
Altimmune Announces Fourth Quarter and Full Year 2024 Financial Results and Provides a Business Update
ALT
Published: February 27, 2025 by: GlobeNewsWire
Sentiment: Neutral

Top-line data from Phase 2b IMPACT trial of pemvidutide in metabolic dysfunction-associated steatohepatitis (MASH) to be reported in Q2 2025 Investigational New Drug (IND) applications in two additional indications have received FDA clearance, with Phase 2 trials to commence mid-2025 Company to hold virtual R&D Day on March 13, 2025. Program will include KOL presentations on pemvidutide development in obesity, MASH and additional indications Two pharmaceutical industry veterans added to Company Board of Directors Cash, cash equivalents and short-term investments of $131.9 million on December 31, 2024 Webcast to be held today, February 27, 2025, at 8:30 a.m.

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image for news Altimmune Announces Fourth Quarter and Full Year 2024 Financial Results and Provides a Business Update
Altimmune's Catalytic Moment In 2025: Pemvidutide's Phase 2b Trial In MASH
ALT
Published: February 18, 2025 by: Seeking Alpha
Sentiment: Positive

Altimmune is a single-molecule company currently trading at a $0.5 billion market cap with a favorable risk-reward profile. The company's existence depends almost entirely on the outcome of the Phase 2 trial for pemvidutide in MASH (metabolic dysfunction-associated steatohepatitis). Pemvidutide has successfully completed a Phase 1 trial for a related liver disease but has yet to demonstrate efficacy in the target indication of MASH.

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image for news Altimmune's Catalytic Moment In 2025: Pemvidutide's Phase 2b Trial In MASH

About Altimmune, Inc. (ALT)

  • IPO Date 2017-05-26
  • Website https://altimmune.com
  • Industry Biotechnology
  • CEO Vipin K. Garg
  • Employees 59

Altimmune, Inc., a clinical stage biopharmaceutical company, focuses on developing treatments for obesity and liver diseases. The company's lead product candidate, pemvidutide (proposed INN, formerly known as ALT-801), is a GLP-1/glucagon dual receptor agonist that is in Phase 1b trial for the treatment of obesity and non-alcoholic steatohepatitis. It is also developing HepTcell, an immunotherapeutic product candidate, which is in Phase 2 clinical trial for patients chronically infected with the hepatitis B virus. The company was formerly known as Vaxin Inc. and changed its name to Altimmune, Inc. in September 2015. Altimmune, Inc. was founded in 1997 is headquartered in Gaithersburg, Maryland.